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Post-Essential Thrombocythemia Myelofibrosis

MedGen UID:
923817
Concept ID:
C3805233
Neoplastic Process
Synonyms: Myelofibrosis due to and following essential thrombocythemia; Myelofibrosis Transformation in Essential Thrombocythemia; Post-essential thrombocythemia myelofibrosis; Post-ET MF; Post-ET Myelofibrosis
SNOMED CT: Post-essential thrombocythemia myelofibrosis (871541008); Myelofibrosis due to and following essential thrombocythemia (871541008)

Definition

Myelofibrosis that develops in a patient with history of essential thrombocythemia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPost-Essential Thrombocythemia Myelofibrosis

Professional guidelines

PubMed

Puglianini OC, Peker D, Zhang L, Papadantonakis N
Lab Med 2023 Jan 5;54(1):13-22. doi: 10.1093/labmed/lmac074. PMID: 35960786
Krauth MT, Burgstaller S, Buxhofer-Ausch V, Gastl G, Geissler K, Keil F, Krippl P, Melchardt T, Petzer A, Rumpold H, Sliwa T, Wöhrer S, Wölfler A, Gisslinger H
Wien Klin Wochenschr 2018 Sep;130(17-18):495-504. Epub 2018 Jul 24 doi: 10.1007/s00508-018-1365-5. PMID: 30043249Free PMC Article
Shreenivas A, Mascarenhas J
Expert Opin Emerg Drugs 2018 Mar;23(1):37-49. Epub 2018 Mar 6 doi: 10.1080/14728214.2018.1445718. PMID: 29480036

Recent clinical studies

Etiology

Lamb YN
Drugs 2022 May;82(7):831-838. doi: 10.1007/s40265-022-01718-y. PMID: 35567653
Blair HA
Drugs 2019 Oct;79(15):1719-1725. doi: 10.1007/s40265-019-01205-x. PMID: 31571162
Passamonti F, Giorgino T, Mora B, Guglielmelli P, Rumi E, Maffioli M, Rambaldi A, Caramella M, Komrokji R, Gotlib J, Kiladjian JJ, Cervantes F, Devos T, Palandri F, De Stefano V, Ruggeri M, Silver RT, Benevolo G, Albano F, Caramazza D, Merli M, Pietra D, Casalone R, Rotunno G, Barbui T, Cazzola M, Vannucchi AM
Leukemia 2017 Dec;31(12):2726-2731. Epub 2017 May 31 doi: 10.1038/leu.2017.169. PMID: 28561069
Bose P, Verstovsek S
Cancer 2016 Mar 1;122(5):681-92. Epub 2015 Dec 30 doi: 10.1002/cncr.29842. PMID: 26717494
Harrison C, Kiladjian JJ, Al-Ali HK, Gisslinger H, Waltzman R, Stalbovskaya V, McQuitty M, Hunter DS, Levy R, Knoops L, Cervantes F, Vannucchi AM, Barbui T, Barosi G
N Engl J Med 2012 Mar 1;366(9):787-98. doi: 10.1056/NEJMoa1110556. PMID: 22375970

Diagnosis

Shide K, Takenaka K, Kitanaka A, Numata A, Kameda T, Yamauchi T, Inagaki A, Mizuno S, Takami A, Ito S, Hagihara M, Usuki K, Maekawa T, Sunami K, Ueda Y, Tsutsui M, Ando M, Komatsu N, Ozawa K, Kurokawa M, Arai S, Mitani K, Akashi K, Shimoda K
Ann Hematol 2024 Jan;103(1):97-103. Epub 2023 Nov 10 doi: 10.1007/s00277-023-05528-4. PMID: 37946031
Puglianini OC, Peker D, Zhang L, Papadantonakis N
Lab Med 2023 Jan 5;54(1):13-22. doi: 10.1093/labmed/lmac074. PMID: 35960786
Masarova L, Verstovsek S
Clin Adv Hematol Oncol 2019 May;17(5):299-307. PMID: 31188809
Passamonti F, Giorgino T, Mora B, Guglielmelli P, Rumi E, Maffioli M, Rambaldi A, Caramella M, Komrokji R, Gotlib J, Kiladjian JJ, Cervantes F, Devos T, Palandri F, De Stefano V, Ruggeri M, Silver RT, Benevolo G, Albano F, Caramazza D, Merli M, Pietra D, Casalone R, Rotunno G, Barbui T, Cazzola M, Vannucchi AM
Leukemia 2017 Dec;31(12):2726-2731. Epub 2017 May 31 doi: 10.1038/leu.2017.169. PMID: 28561069
Bose P, Verstovsek S
Cancer 2016 Mar 1;122(5):681-92. Epub 2015 Dec 30 doi: 10.1002/cncr.29842. PMID: 26717494

Therapy

Mora B, Guglielmelli P, Kuykendall A, Rumi E, Maffioli M, Palandri F, De Stefano V, Caramella M, Salmoiraghi S, Kiladjian JJ, Gotlib J, Iurlo A, Cervantes F, Ruggeri M, Silver RT, Albano F, Benevolo G, Ross DM, Della Porta MG, Devos T, Rotunno G, Komrokji RS, Casetti IC, Merli M, Brociner M, Caramazza D, Auteri G, Barbui T, Cattaneo D, Bertù L, Arcaini L, Vannucchi AM, Passamonti F
Leukemia 2022 Oct;36(10):2453-2460. Epub 2022 Aug 30 doi: 10.1038/s41375-022-01673-3. PMID: 36042316
Lamb YN
Drugs 2022 May;82(7):831-838. doi: 10.1007/s40265-022-01718-y. PMID: 35567653
Blair HA
Drugs 2019 Oct;79(15):1719-1725. doi: 10.1007/s40265-019-01205-x. PMID: 31571162
Passamonti F, Giorgino T, Mora B, Guglielmelli P, Rumi E, Maffioli M, Rambaldi A, Caramella M, Komrokji R, Gotlib J, Kiladjian JJ, Cervantes F, Devos T, Palandri F, De Stefano V, Ruggeri M, Silver RT, Benevolo G, Albano F, Caramazza D, Merli M, Pietra D, Casalone R, Rotunno G, Barbui T, Cazzola M, Vannucchi AM
Leukemia 2017 Dec;31(12):2726-2731. Epub 2017 May 31 doi: 10.1038/leu.2017.169. PMID: 28561069
Harrison C, Kiladjian JJ, Al-Ali HK, Gisslinger H, Waltzman R, Stalbovskaya V, McQuitty M, Hunter DS, Levy R, Knoops L, Cervantes F, Vannucchi AM, Barbui T, Barosi G
N Engl J Med 2012 Mar 1;366(9):787-98. doi: 10.1056/NEJMoa1110556. PMID: 22375970

Prognosis

Shide K, Takenaka K, Kitanaka A, Numata A, Kameda T, Yamauchi T, Inagaki A, Mizuno S, Takami A, Ito S, Hagihara M, Usuki K, Maekawa T, Sunami K, Ueda Y, Tsutsui M, Ando M, Komatsu N, Ozawa K, Kurokawa M, Arai S, Mitani K, Akashi K, Shimoda K
Ann Hematol 2024 Jan;103(1):97-103. Epub 2023 Nov 10 doi: 10.1007/s00277-023-05528-4. PMID: 37946031
Puglianini OC, Peker D, Zhang L, Papadantonakis N
Lab Med 2023 Jan 5;54(1):13-22. doi: 10.1093/labmed/lmac074. PMID: 35960786
Passamonti F, Giorgino T, Mora B, Guglielmelli P, Rumi E, Maffioli M, Rambaldi A, Caramella M, Komrokji R, Gotlib J, Kiladjian JJ, Cervantes F, Devos T, Palandri F, De Stefano V, Ruggeri M, Silver RT, Benevolo G, Albano F, Caramazza D, Merli M, Pietra D, Casalone R, Rotunno G, Barbui T, Cazzola M, Vannucchi AM
Leukemia 2017 Dec;31(12):2726-2731. Epub 2017 May 31 doi: 10.1038/leu.2017.169. PMID: 28561069
Bose P, Verstovsek S
Cancer 2016 Mar 1;122(5):681-92. Epub 2015 Dec 30 doi: 10.1002/cncr.29842. PMID: 26717494
Harrison C, Kiladjian JJ, Al-Ali HK, Gisslinger H, Waltzman R, Stalbovskaya V, McQuitty M, Hunter DS, Levy R, Knoops L, Cervantes F, Vannucchi AM, Barbui T, Barosi G
N Engl J Med 2012 Mar 1;366(9):787-98. doi: 10.1056/NEJMoa1110556. PMID: 22375970

Clinical prediction guides

Puglianini OC, Peker D, Zhang L, Papadantonakis N
Lab Med 2023 Jan 5;54(1):13-22. doi: 10.1093/labmed/lmac074. PMID: 35960786
Mora B, Guglielmelli P, Kuykendall A, Rumi E, Maffioli M, Palandri F, De Stefano V, Caramella M, Salmoiraghi S, Kiladjian JJ, Gotlib J, Iurlo A, Cervantes F, Ruggeri M, Silver RT, Albano F, Benevolo G, Ross DM, Della Porta MG, Devos T, Rotunno G, Komrokji RS, Casetti IC, Merli M, Brociner M, Caramazza D, Auteri G, Barbui T, Cattaneo D, Bertù L, Arcaini L, Vannucchi AM, Passamonti F
Leukemia 2022 Oct;36(10):2453-2460. Epub 2022 Aug 30 doi: 10.1038/s41375-022-01673-3. PMID: 36042316
Passamonti F, Giorgino T, Mora B, Guglielmelli P, Rumi E, Maffioli M, Rambaldi A, Caramella M, Komrokji R, Gotlib J, Kiladjian JJ, Cervantes F, Devos T, Palandri F, De Stefano V, Ruggeri M, Silver RT, Benevolo G, Albano F, Caramazza D, Merli M, Pietra D, Casalone R, Rotunno G, Barbui T, Cazzola M, Vannucchi AM
Leukemia 2017 Dec;31(12):2726-2731. Epub 2017 May 31 doi: 10.1038/leu.2017.169. PMID: 28561069
Bose P, Verstovsek S
Cancer 2016 Mar 1;122(5):681-92. Epub 2015 Dec 30 doi: 10.1002/cncr.29842. PMID: 26717494
Chen X, Williams WV, Sandor V, Yeleswaram S
J Clin Pharmacol 2013 Jul;53(7):721-30. Epub 2013 May 16 doi: 10.1002/jcph.102. PMID: 23677817

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