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Ovarian Cancer by FIGO Stage

MedGen UID:
925359
•Concept ID:
C4287827
•
Neoplastic Process
Synonym: Ovarian Carcinoma by FIGO Stage 2014

Definition

A category of staging terms for ovarian cancer according to the International Federation of Gynecology and Obstetrics (FIGO), 2014. AJCC ovarian cancer stage terms from the 6th and 7th editions that are synonymous to the FIGO ovarian cancer staging classification of 2014 are included as preferred terms. [from NCI]

Professional guidelines

PubMed

Update on MRI in Evaluation and Treatment of Endometrial Cancer.
Maheshwari E, Nougaret S, Stein EB, Rauch GM, Hwang KP, Stafford RJ, Klopp AH, Soliman PT, Maturen KE, Rockall AG, Lee SI, Sadowski EA, Venkatesan AM
Radiographics 2022 Nov-Dec;42(7):2112-2130. Epub 2022 Aug 26 doi: 10.1148/rg.220070. PMID: 36018785
Neoadjuvant chemotherapy before surgery versus surgery followed by chemotherapy for initial treatment in advanced ovarian epithelial cancer.
Coleridge SL, Bryant A, Kehoe S, Morrison J
Cochrane Database Syst Rev 2021 Jul 30;7(7):CD005343. doi: 10.1002/14651858.CD005343.pub6. PMID: 34328210Free PMC Article
Management of borderline ovarian tumours.
Gershenson DM
Best Pract Res Clin Obstet Gynaecol 2017 May;41:49-59. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.09.012. PMID: 27780698

Recent clinical studies

Etiology

TRUST: Trial of Radical Upfront Surgical Therapy in advanced ovarian cancer (ENGOT ov33/AGO-OVAR OP7).
Reuss A, du Bois A, Harter P, Fotopoulou C, Sehouli J, Aletti G, Guyon F, Greggi S, Mosgaard BJ, Reinthaller A, Hilpert F, Schade-Brittinger C, Chi DS, Mahner S
Int J Gynecol Cancer 2019 Oct;29(8):1327-1331. Epub 2019 Aug 15 doi: 10.1136/ijgc-2019-000682. PMID: 31420412
The new classifications of ovarian, fallopian tube, and primary peritoneal cancer and their clinical implications.
Duska LR, Kohn EC
Ann Oncol 2017 Nov 1;28(suppl_8):viii8-viii12. doi: 10.1093/annonc/mdx445. PMID: 29232468Free PMC Article
Laparoscopy versus laparotomy for FIGO stage I ovarian cancer.
Falcetta FS, Lawrie TA, Medeiros LR, da Rosa MI, Edelweiss MI, Stein AT, Zelmanowicz A, Moraes AB, Zanini RR, Rosa DD
Cochrane Database Syst Rev 2016 Oct 13;10(10):CD005344. doi: 10.1002/14651858.CD005344.pub4. PMID: 27737492Free PMC Article
Ovarian Cancer, the Revised FIGO Staging System, and the Role of Imaging.
Javadi S, Ganeshan DM, Qayyum A, Iyer RB, Bhosale P
AJR Am J Roentgenol 2016 Jun;206(6):1351-60. Epub 2016 Apr 4 doi: 10.2214/AJR.15.15199. PMID: 27042752
Laparoscopy versus laparotomy for FIGO stage I ovarian cancer.
Lawrie TA, Medeiros LR, Rosa DD, da Rosa MI, Edelweiss MI, Stein AT, Zelmanowicz A, Ethur AB, Zanini RR
Cochrane Database Syst Rev 2013 Feb 28;(2):CD005344. doi: 10.1002/14651858.CD005344.pub3. PMID: 23450560

Diagnosis

Clinical Staging of Ovarian Cancer.
O'Shea AS
Methods Mol Biol 2022;2424:3-10. doi: 10.1007/978-1-0716-1956-8_1. PMID: 34918284
TRUST: Trial of Radical Upfront Surgical Therapy in advanced ovarian cancer (ENGOT ov33/AGO-OVAR OP7).
Reuss A, du Bois A, Harter P, Fotopoulou C, Sehouli J, Aletti G, Guyon F, Greggi S, Mosgaard BJ, Reinthaller A, Hilpert F, Schade-Brittinger C, Chi DS, Mahner S
Int J Gynecol Cancer 2019 Oct;29(8):1327-1331. Epub 2019 Aug 15 doi: 10.1136/ijgc-2019-000682. PMID: 31420412
FIGO stage IV epithelial ovarian, fallopian tube and peritoneal cancer revisited.
Ataseven B, Chiva LM, Harter P, Gonzalez-Martin A, du Bois A
Gynecol Oncol 2016 Sep;142(3):597-607. Epub 2016 Jun 19 doi: 10.1016/j.ygyno.2016.06.013. PMID: 27335253
Ovarian Cancer, the Revised FIGO Staging System, and the Role of Imaging.
Javadi S, Ganeshan DM, Qayyum A, Iyer RB, Bhosale P
AJR Am J Roentgenol 2016 Jun;206(6):1351-60. Epub 2016 Apr 4 doi: 10.2214/AJR.15.15199. PMID: 27042752
Ovarian cancer.
Jayson GC, Kohn EC, Kitchener HC, Ledermann JA
Lancet 2014 Oct 11;384(9951):1376-88. Epub 2014 Apr 21 doi: 10.1016/S0140-6736(13)62146-7. PMID: 24767708

Therapy

Validation of ESM1 Related to Ovarian Cancer and the Biological Function and Prognostic Significance.
Li YK, Zeng T, Guan Y, Liu J, Liao NC, Wang MJ, Chen KX, Luo XY, Chen CY, Quan FF, Wang J, Zhang QF, Zou J
Int J Biol Sci 2023;19(1):258-280. Epub 2023 Jan 1 doi: 10.7150/ijbs.66839. PMID: 36594088Free PMC Article
Atezolizumab, Bevacizumab, and Chemotherapy for Newly Diagnosed Stage III or IV Ovarian Cancer: Placebo-Controlled Randomized Phase III Trial (IMagyn050/GOG 3015/ENGOT-OV39).
Moore KN, Bookman M, Sehouli J, Miller A, Anderson C, Scambia G, Myers T, Taskiran C, Robison K, Mäenpää J, Willmott L, Colombo N, Thomes-Pepin J, Liontos M, Gold MA, Garcia Y, Sharma SK, Darus CJ, Aghajanian C, Okamoto A, Wu X, Safin R, Wu F, Molinero L, Maiya V, Khor VK, Lin YG, Pignata S
J Clin Oncol 2021 Jun 10;39(17):1842-1855. Epub 2021 Apr 23 doi: 10.1200/JCO.21.00306. PMID: 33891472Free PMC Article
Management of borderline ovarian tumours.
Gershenson DM
Best Pract Res Clin Obstet Gynaecol 2017 May;41:49-59. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.09.012. PMID: 27780698
Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial.
Oza AM, Cook AD, Pfisterer J, Embleton A, Ledermann JA, Pujade-Lauraine E, Kristensen G, Carey MS, Beale P, Cervantes A, Park-Simon TW, Rustin G, Joly F, Mirza MR, Plante M, Quinn M, Poveda A, Jayson GC, Stark D, Swart AM, Farrelly L, Kaplan R, Parmar MK, Perren TJ; ICON7 trial investigators
Lancet Oncol 2015 Aug;16(8):928-36. Epub 2015 Jun 23 doi: 10.1016/S1470-2045(15)00086-8. PMID: 26115797Free PMC Article
Ovarian cancer.
Jayson GC, Kohn EC, Kitchener HC, Ledermann JA
Lancet 2014 Oct 11;384(9951):1376-88. Epub 2014 Apr 21 doi: 10.1016/S0140-6736(13)62146-7. PMID: 24767708

Prognosis

Clinical Staging of Ovarian Cancer.
O'Shea AS
Methods Mol Biol 2022;2424:3-10. doi: 10.1007/978-1-0716-1956-8_1. PMID: 34918284
Cancer of the ovary, fallopian tube, and peritoneum: 2021 update.
Berek JS, Renz M, Kehoe S, Kumar L, Friedlander M
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):61-85. doi: 10.1002/ijgo.13878. PMID: 34669199Free PMC Article
Low-grade epithelial ovarian cancer: what a radiologist should know.
Elsherif S, Javadi S, Viswanathan C, Faria S, Bhosale P
Br J Radiol 2019 Mar;92(1095):20180571. Epub 2019 Jan 31 doi: 10.1259/bjr.20180571. PMID: 30604635Free PMC Article
Imaging in the pre-operative staging of ovarian cancer.
Castellani F, Nganga EC, Dumas L, Banerjee S, Rockall AG
Abdom Radiol (NY) 2019 Feb;44(2):685-696. doi: 10.1007/s00261-018-1779-6. PMID: 30229424
Ovarian Cancer, the Revised FIGO Staging System, and the Role of Imaging.
Javadi S, Ganeshan DM, Qayyum A, Iyer RB, Bhosale P
AJR Am J Roentgenol 2016 Jun;206(6):1351-60. Epub 2016 Apr 4 doi: 10.2214/AJR.15.15199. PMID: 27042752

Clinical prediction guides

FIGO stage IV epithelial ovarian, fallopian tube and peritoneal cancer revisited.
Ataseven B, Chiva LM, Harter P, Gonzalez-Martin A, du Bois A
Gynecol Oncol 2016 Sep;142(3):597-607. Epub 2016 Jun 19 doi: 10.1016/j.ygyno.2016.06.013. PMID: 27335253
Ovarian cancer in Lynch syndrome; a systematic review.
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421
Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer.
Lawrie TA, Winter-Roach BA, Heus P, Kitchener HC
Cochrane Database Syst Rev 2015 Dec 17;2015(12):CD004706. doi: 10.1002/14651858.CD004706.pub5. PMID: 26676202Free PMC Article
The impact of pleural disease on the management of advanced ovarian cancer.
Escayola C, Ferron G, Romeo M, Torrent JJ, Querleu D
Gynecol Oncol 2015 Jul;138(1):216-20. Epub 2015 May 9 doi: 10.1016/j.ygyno.2015.05.003. PMID: 25969350
Laparoscopy versus laparotomy for FIGO Stage I ovarian cancer.
Medeiros LR, Rosa DD, Bozzetti MC, Rosa MI, Edelweiss MI, Stein AT, Zelmanowicz A, Ethur AB, Zanini RR
Cochrane Database Syst Rev 2008 Oct 8;(4):CD005344. doi: 10.1002/14651858.CD005344.pub2. PMID: 18843688

Recent systematic reviews

Neoadjuvant chemotherapy before surgery versus surgery followed by chemotherapy for initial treatment in advanced ovarian epithelial cancer.
Coleridge SL, Bryant A, Kehoe S, Morrison J
Cochrane Database Syst Rev 2021 Jul 30;7(7):CD005343. doi: 10.1002/14651858.CD005343.pub6. PMID: 34328210Free PMC Article
Laparoscopy versus laparotomy for FIGO stage I ovarian cancer.
Falcetta FS, Lawrie TA, Medeiros LR, da Rosa MI, Edelweiss MI, Stein AT, Zelmanowicz A, Moraes AB, Zanini RR, Rosa DD
Cochrane Database Syst Rev 2016 Oct 13;10(10):CD005344. doi: 10.1002/14651858.CD005344.pub4. PMID: 27737492Free PMC Article
Fertility-sparing surgery in epithelial ovarian cancer: a systematic review of oncological issues.
Bentivegna E, Gouy S, Maulard A, Pautier P, Leary A, Colombo N, Morice P
Ann Oncol 2016 Nov;27(11):1994-2004. Epub 2016 Aug 8 doi: 10.1093/annonc/mdw311. PMID: 27502723
Ovarian cancer in Lynch syndrome; a systematic review.
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421
Laparoscopy versus laparotomy for FIGO stage I ovarian cancer.
Lawrie TA, Medeiros LR, Rosa DD, da Rosa MI, Edelweiss MI, Stein AT, Zelmanowicz A, Ethur AB, Zanini RR
Cochrane Database Syst Rev 2013 Feb 28;(2):CD005344. doi: 10.1002/14651858.CD005344.pub3. PMID: 23450560

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