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Vulvar Superficial Myofibroblastoma

MedGen UID:
925378
Concept ID:
C4287846
Neoplastic Process

Definition

An uncommon benign polypoid or nodular mesenchymal neoplasm that arises in the vulvar region. It is characterized by the presence of oval or spindle-shaped cells in a collagenous stroma and is separated from the epidermis by a variably thick Grenz zone. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar Superficial Myofibroblastoma

Recent clinical studies

Etiology

Zhang M, Shi P, Zhou B, Liu J, Li L
Ann Diagn Pathol 2022 Oct;60:152010. Epub 2022 Jul 22 doi: 10.1016/j.anndiagpath.2022.152010. PMID: 35907316
Croce S, Perret R, Le Loarer F
Surg Pathol Clin 2022 Jun;15(2):341-367. Epub 2022 May 20 doi: 10.1016/j.path.2022.02.009. PMID: 35715165
McCluggage WG
Int J Gynecol Pathol 2005 Jan;24(1):26-38. PMID: 15626915
Laskin WB, Fetsch JF, Tavassoli FA
Hum Pathol 2001 Jul;32(7):715-25. doi: 10.1053/hupa.2001.25588. PMID: 11486170
Garijo MF, Val-Bernal JF
J Cutan Pathol 1998 Jul;25(6):327-32. doi: 10.1111/j.1600-0560.1998.tb01754.x. PMID: 9694623

Diagnosis

Tan QT, Morgan T, Scurry JP
BMJ Case Rep 2023 Nov 30;16(11) doi: 10.1136/bcr-2022-248800. PMID: 38035683Free PMC Article
Zhang M, Shi P, Zhou B, Liu J, Li L
Ann Diagn Pathol 2022 Oct;60:152010. Epub 2022 Jul 22 doi: 10.1016/j.anndiagpath.2022.152010. PMID: 35907316
Croce S, Perret R, Le Loarer F
Surg Pathol Clin 2022 Jun;15(2):341-367. Epub 2022 May 20 doi: 10.1016/j.path.2022.02.009. PMID: 35715165
McCluggage WG
Histopathology 2009 Jan;54(2):156-73. doi: 10.1111/j.1365-2559.2008.03098.x. PMID: 18637148
Nucci MR, Fletcher CD
Histopathology 2000 Feb;36(2):97-108. doi: 10.1046/j.1365-2559.2000.00865.x. PMID: 10672053

Therapy

Abdou AH, Li L, Khatib-Chahidi K, Troja A, Looft P, Gudewer EM, Raab HR, Antolovic D
Int J Colorectal Dis 2016 Feb;31(2):385-91. Epub 2015 Sep 26 doi: 10.1007/s00384-015-2402-8. PMID: 26410267

Prognosis

Tan QT, Morgan T, Scurry JP
BMJ Case Rep 2023 Nov 30;16(11) doi: 10.1136/bcr-2022-248800. PMID: 38035683Free PMC Article
McCluggage WG
Histopathology 2009 Jan;54(2):156-73. doi: 10.1111/j.1365-2559.2008.03098.x. PMID: 18637148
Laskin WB, Fetsch JF, Tavassoli FA
Hum Pathol 2001 Jul;32(7):715-25. doi: 10.1053/hupa.2001.25588. PMID: 11486170
Nucci MR, Fletcher CD
Histopathology 2000 Feb;36(2):97-108. doi: 10.1046/j.1365-2559.2000.00865.x. PMID: 10672053
Fetsch JF, Laskin WB, Tavassoli FA
Int J Gynecol Pathol 1997 Oct;16(4):325-34. doi: 10.1097/00004347-199710000-00006. PMID: 9421071

Clinical prediction guides

Zhang M, Shi P, Zhou B, Liu J, Li L
Ann Diagn Pathol 2022 Oct;60:152010. Epub 2022 Jul 22 doi: 10.1016/j.anndiagpath.2022.152010. PMID: 35907316
Harkness R, McCluggage WG
Int J Gynecol Pathol 2021 Mar 1;40(2):185-189. doi: 10.1097/PGP.0000000000000689. PMID: 32897956
Flucke U, van Krieken JH, Mentzel T
Mod Pathol 2011 Jan;24(1):82-9. Epub 2010 Sep 17 doi: 10.1038/modpathol.2010.170. PMID: 20852591
McCluggage WG
Histopathology 2009 Jan;54(2):156-73. doi: 10.1111/j.1365-2559.2008.03098.x. PMID: 18637148
Nucci MR, Fletcher CD
Histopathology 2000 Feb;36(2):97-108. doi: 10.1046/j.1365-2559.2000.00865.x. PMID: 10672053

Recent systematic reviews

Zhang M, Shi P, Zhou B, Liu J, Li L
Ann Diagn Pathol 2022 Oct;60:152010. Epub 2022 Jul 22 doi: 10.1016/j.anndiagpath.2022.152010. PMID: 35907316

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