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Cervical Transitional Metaplasia

MedGen UID:
925433
Concept ID:
C4287901
Finding

Definition

Cervical metaplasia in which the cervical squamous epithelium resembles benign urothelium as a result of a lack of cellular maturation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervical Transitional Metaplasia

Recent clinical studies

Etiology

Lin LH, Hernandez A, Marcus A, Deng FM, Adler E
Arch Pathol Lab Med 2022 Jun 1;146(6):742-748. doi: 10.5858/arpa.2021-0199-OA. PMID: 34591101
Williams MPA, Kukkar V, Stemmer MN, Khurana KK
Cancer Cytopathol 2020 Jul;128(7):491-498. Epub 2020 Mar 3 doi: 10.1002/cncy.22259. PMID: 32125771
Rajendra S, Sharma P
Dis Esophagus 2019 Jul 1;32(7) doi: 10.1093/dote/doz008. PMID: 31304554
Khalifa MA, Toyama A, Klein ME, Santiago V
Int J Gynecol Pathol 2019 Nov;38(6):520-527. doi: 10.1097/PGP.0000000000000548. PMID: 30252728
Malpica A
Mod Pathol 2016 Jan;29 Suppl 1:S29-44. doi: 10.1038/modpathol.2015.142. PMID: 26715172

Diagnosis

Lombardo V, Cartesio S, Fadda G, Rossi ED
Cancer Cytopathol 2023 Feb;131(2):78-82. Epub 2022 Oct 10 doi: 10.1002/cncy.22650. PMID: 36217282
Wang SS, Cen X, Liang XH, Tang YL
Oncotarget 2017 Feb 7;8(6):10650-10661. doi: 10.18632/oncotarget.12890. PMID: 27788497Free PMC Article
Malpica A
Mod Pathol 2016 Jan;29 Suppl 1:S29-44. doi: 10.1038/modpathol.2015.142. PMID: 26715172
Houghton O, McCluggage WG
Adv Anat Pathol 2009 Sep;16(5):316-21. doi: 10.1097/PAP.0b013e3181b507c6. PMID: 19700941
Duggan MA
Mod Pathol 2000 Mar;13(3):252-60. doi: 10.1038/modpathol.3880046. PMID: 10757336

Therapy

Serafim Junior V, Fernandes GMM, Oliveira-Cucolo JG, Pavarino EC, Goloni-Bertollo EM
Cytokine 2020 Dec;136:155270. Epub 2020 Sep 7 doi: 10.1016/j.cyto.2020.155270. PMID: 32911446
Rajendra S, Sharma P
Dis Esophagus 2019 Jul 1;32(7) doi: 10.1093/dote/doz008. PMID: 31304554
Hsiao YH, Hsieh MJ, Yang SF, Chen SP, Tsai WC, Chen PN
Phytomedicine 2019 Sep;62:152964. Epub 2019 May 18 doi: 10.1016/j.phymed.2019.152964. PMID: 31153059
Khalifa MA, Toyama A, Klein ME, Santiago V
Int J Gynecol Pathol 2019 Nov;38(6):520-527. doi: 10.1097/PGP.0000000000000548. PMID: 30252728
Bagnato A, Spinella F, Rosanò L
Can J Physiol Pharmacol 2008 Aug;86(8):473-84. doi: 10.1139/Y08-058. PMID: 18758494

Prognosis

Serafim Junior V, Fernandes GMM, Oliveira-Cucolo JG, Pavarino EC, Goloni-Bertollo EM
Cytokine 2020 Dec;136:155270. Epub 2020 Sep 7 doi: 10.1016/j.cyto.2020.155270. PMID: 32911446
Agnihotri NS, Astekar M
J Exp Ther Oncol 2018 May;12(3):171-184. PMID: 29790306
Malpica A
Mod Pathol 2016 Jan;29 Suppl 1:S29-44. doi: 10.1038/modpathol.2015.142. PMID: 26715172
Albert S, Riveiro ME, Halimi C, Hourseau M, Couvelard A, Serova M, Barry B, Raymond E, Faivre S
Head Neck 2013 Dec;35(12):1819-28. Epub 2013 Mar 6 doi: 10.1002/hed.23217. PMID: 23468253
Albores-Saavedra J, Young RH
Am J Surg Pathol 1995 Oct;19(10):1138-45. PMID: 7573672

Clinical prediction guides

Shin JM, Yang HW, Park JH, Kim TH
Int J Mol Sci 2023 Feb 16;24(4) doi: 10.3390/ijms24044017. PMID: 36835423Free PMC Article
Regauer S, Reich O, Kashofer K
Am J Surg Pathol 2022 Apr 1;46(4):519-527. doi: 10.1097/PAS.0000000000001818. PMID: 34619706
Talia KL, Arora R, McCluggage WG
Int J Gynecol Pathol 2022 Mar 1;41(2):105-112. doi: 10.1097/PGP.0000000000000785. PMID: 33770055
Khalifa MA, Toyama A, Klein ME, Santiago V
Int J Gynecol Pathol 2019 Nov;38(6):520-527. doi: 10.1097/PGP.0000000000000548. PMID: 30252728
Hittelman WN
Ann N Y Acad Sci 2001 Dec;952:1-12. doi: 10.1111/j.1749-6632.2001.tb02723.x. PMID: 11795428

Recent systematic reviews

Andrews AR, Kakadekar A, Greene DN, Khalifa MA, Santiago V, Schmidt RL
Arch Pathol Lab Med 2022 Jun 1;146(6):766-779. doi: 10.5858/arpa.2020-0774-RA. PMID: 34559874

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