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t(2;13)

MedGen UID:
925473
•Concept ID:
C4287941
•
Cell or Molecular Dysfunction

Definition

A cytogenetic abnormality that involves a translocation between chromosomes 2 and 13. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(2;13)

Professional guidelines

PubMed

Hospitalizations due to primary care sensitive conditions: an ecological study.
Maia LG, Silva LAD, Guimarães RA, Pelazza BB, Pereira ACS, Rezende WL, Barbosa MA
Rev Saude Publica 2018 Dec 20;53:02. doi: 10.11606/S1518-8787.2019053000403. PMID: 30652775Free PMC Article
A rational approach to genetic testing for sarcoma.
Gulley ML, Kaiser-Rogers KA
Diagn Mol Pathol 2009 Mar;18(1):1-10. doi: 10.1097/PDM.0b013e318181fa05. PMID: 19214114
Risk-based management: current concepts of treating malignant solid tumors of childhood.
Grosfeld JL
J Am Coll Surg 1999 Oct;189(4):407-25. doi: 10.1016/s1072-7515(99)00167-2. PMID: 10509467

Recent clinical studies

Etiology

Individuals with and without military-related PTSD differ in subjective sleepiness and alertness but not objective sleepiness.
LaGoy AD, Sphar M, Connaboy C, Dretsch MN, Ferrarelli F, Laxminarayan S, Ramakrishnan S, Wang C, Reifman J, Germain A
J Psychiatr Res 2021 Sep;141:301-308. Epub 2021 Jul 14 doi: 10.1016/j.jpsychires.2021.07.017. PMID: 34304033Free PMC Article
A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED).
Parletta N, Zarnowiecki D, Cho J, Wilson A, Bogomolova S, Villani A, Itsiopoulos C, Niyonsenga T, Blunden S, Meyer B, Segal L, Baune BT, O'Dea K
Nutr Neurosci 2019 Jul;22(7):474-487. Epub 2017 Dec 7 doi: 10.1080/1028415X.2017.1411320. PMID: 29215971
Future directions in risk stratification and therapy for advanced pediatric genitourinary rhabdomyosarcoma.
Harel M, Ferrer FA, Shapiro LH, Makari JH
Urol Oncol 2016 Feb;34(2):103-15. Epub 2015 Oct 28 doi: 10.1016/j.urolonc.2015.09.013. PMID: 26519985
Genes, chromosomes, and rhabdomyosarcoma.
Anderson J, Gordon A, Pritchard-Jones K, Shipley J
Genes Chromosomes Cancer 1999 Dec;26(4):275-85. PMID: 10534762
The role of cytogenetics in the classification of soft tissue tumours.
Dei Tos AP, Dal Cin P
Virchows Arch 1997 Aug;431(2):83-94. doi: 10.1007/s004280050073. PMID: 9293889

Diagnosis

A Review of Effusion Cytomorphology of Small Round Cell Tumors.
Han LM, VandenBussche CJ, Abildtrup M, Chandra A, Vohra P
Acta Cytol 2022;66(4):336-346. Epub 2021 Jul 2 doi: 10.1159/000516497. PMID: 34218227
Difficult life events affect lower extremity illness.
Al Salman A, Khatiri MZ, Cremers T, Ring D, Thomas JE, Fatehi A
Arch Orthop Trauma Surg 2022 Apr;142(4):599-605. Epub 2020 Nov 20 doi: 10.1007/s00402-020-03686-y. PMID: 33216183
A rational approach to genetic testing for sarcoma.
Gulley ML, Kaiser-Rogers KA
Diagn Mol Pathol 2009 Mar;18(1):1-10. doi: 10.1097/PDM.0b013e318181fa05. PMID: 19214114
Molecular biology of rhabdomyosarcoma.
Gallego Melcón S, Sánchez de Toledo Codina J
Clin Transl Oncol 2007 Jul;9(7):415-9. doi: 10.1007/s12094-007-0079-3. PMID: 17652054
The role of cytogenetics in the classification of soft tissue tumours.
Dei Tos AP, Dal Cin P
Virchows Arch 1997 Aug;431(2):83-94. doi: 10.1007/s004280050073. PMID: 9293889

Therapy

A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED).
Parletta N, Zarnowiecki D, Cho J, Wilson A, Bogomolova S, Villani A, Itsiopoulos C, Niyonsenga T, Blunden S, Meyer B, Segal L, Baune BT, O'Dea K
Nutr Neurosci 2019 Jul;22(7):474-487. Epub 2017 Dec 7 doi: 10.1080/1028415X.2017.1411320. PMID: 29215971
Therapeutic Approaches Targeting PAX3-FOXO1 and Its Regulatory and Transcriptional Pathways in Rhabdomyosarcoma.
Nguyen TH, Barr FG
Molecules 2018 Oct 28;23(11) doi: 10.3390/molecules23112798. PMID: 30373318Free PMC Article
Functional electrical stimulation improves quality of life by reducing intermittent claudication.
Embrey DG, Alon G, Brandsma BA, Vladimir F, Silva A, Pflugeisen BM, Amoroso PJ
Int J Cardiol 2017 Sep 15;243:454-459. Epub 2017 Jun 2 doi: 10.1016/j.ijcard.2017.05.097. PMID: 28595744Free PMC Article
Psychological and educational interventions for atopic eczema in children.
Ersser SJ, Latter S, Sibley A, Satherley PA, Welbourne S
Cochrane Database Syst Rev 2007 Jul 18;(3):CD004054. doi: 10.1002/14651858.CD004054.pub2. PMID: 17636745
Biology and therapy of pediatric rhabdomyosarcoma.
Pappo AS, Shapiro DN, Crist WM, Maurer HM
J Clin Oncol 1995 Aug;13(8):2123-39. doi: 10.1200/JCO.1995.13.8.2123. PMID: 7636557

Prognosis

A Review of Effusion Cytomorphology of Small Round Cell Tumors.
Han LM, VandenBussche CJ, Abildtrup M, Chandra A, Vohra P
Acta Cytol 2022;66(4):336-346. Epub 2021 Jul 2 doi: 10.1159/000516497. PMID: 34218227
Individuals with and without military-related PTSD differ in subjective sleepiness and alertness but not objective sleepiness.
LaGoy AD, Sphar M, Connaboy C, Dretsch MN, Ferrarelli F, Laxminarayan S, Ramakrishnan S, Wang C, Reifman J, Germain A
J Psychiatr Res 2021 Sep;141:301-308. Epub 2021 Jul 14 doi: 10.1016/j.jpsychires.2021.07.017. PMID: 34304033Free PMC Article
Future directions in risk stratification and therapy for advanced pediatric genitourinary rhabdomyosarcoma.
Harel M, Ferrer FA, Shapiro LH, Makari JH
Urol Oncol 2016 Feb;34(2):103-15. Epub 2015 Oct 28 doi: 10.1016/j.urolonc.2015.09.013. PMID: 26519985
Fusions involving PAX and FOX genes in the molecular pathogenesis of alveolar rhabdomyosarcoma: recent advances.
Mercado GE, Barr FG
Curr Mol Med 2007 Feb;7(1):47-61. doi: 10.2174/156652407779940440. PMID: 17311532
Risk-based management: current concepts of treating malignant solid tumors of childhood.
Grosfeld JL
J Am Coll Surg 1999 Oct;189(4):407-25. doi: 10.1016/s1072-7515(99)00167-2. PMID: 10509467

Clinical prediction guides

Individuals with and without military-related PTSD differ in subjective sleepiness and alertness but not objective sleepiness.
LaGoy AD, Sphar M, Connaboy C, Dretsch MN, Ferrarelli F, Laxminarayan S, Ramakrishnan S, Wang C, Reifman J, Germain A
J Psychiatr Res 2021 Sep;141:301-308. Epub 2021 Jul 14 doi: 10.1016/j.jpsychires.2021.07.017. PMID: 34304033Free PMC Article
Trait Conscientiousness predicts rate of longitudinal SDMT decline in multiple sclerosis.
Fuchs TA, Wojcik C, Wilding GE, Pol J, Dwyer MG, Weinstock-Guttman B, Zivadinov R, Benedict RH
Mult Scler 2020 Feb;26(2):245-252. Epub 2019 Jan 7 doi: 10.1177/1352458518820272. PMID: 30615562
A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED).
Parletta N, Zarnowiecki D, Cho J, Wilson A, Bogomolova S, Villani A, Itsiopoulos C, Niyonsenga T, Blunden S, Meyer B, Segal L, Baune BT, O'Dea K
Nutr Neurosci 2019 Jul;22(7):474-487. Epub 2017 Dec 7 doi: 10.1080/1028415X.2017.1411320. PMID: 29215971
A rational approach to genetic testing for sarcoma.
Gulley ML, Kaiser-Rogers KA
Diagn Mol Pathol 2009 Mar;18(1):1-10. doi: 10.1097/PDM.0b013e318181fa05. PMID: 19214114
The role of cytogenetics in the classification of soft tissue tumours.
Dei Tos AP, Dal Cin P
Virchows Arch 1997 Aug;431(2):83-94. doi: 10.1007/s004280050073. PMID: 9293889

Recent systematic reviews

Serum albumin concentrations are associated with disease severity and outcomes in coronavirus 19 disease (COVID-19): a systematic review and meta-analysis.
Paliogiannis P, Mangoni AA, Cangemi M, Fois AG, Carru C, Zinellu A
Clin Exp Med 2021 Aug;21(3):343-354. Epub 2021 Jan 28 doi: 10.1007/s10238-021-00686-z. PMID: 33511503Free PMC Article
Psychological and educational interventions for atopic eczema in children.
Ersser SJ, Latter S, Sibley A, Satherley PA, Welbourne S
Cochrane Database Syst Rev 2007 Jul 18;(3):CD004054. doi: 10.1002/14651858.CD004054.pub2. PMID: 17636745

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