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Mitral E/e' Ratio

MedGen UID:
926266
•Concept ID:
C4288734
•
Finding

Definition

The ratio of the peak early diastolic transmitral velocity to the peak mitral annular motion velocity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMitral E/e' Ratio

Professional guidelines

PubMed

Fetal echocardiographic evaluation before and after nifedipine treatment in preterm labor.
Menekse Beser D, Oluklu D, Uyan Hendem D, Yildirim M, Tugrul Ersak D, Goncu Ayhan S, Sahin D
Echocardiography 2022 Sep;39(9):1245-1251. Epub 2022 Aug 27 doi: 10.1111/echo.15444. PMID: 36029144
Tailored risk assessment of 90-day acute heart failure readmission or all-cause death to heart failure with preserved versus reduced ejection fraction.
Park J, Zhong X, Babaie Sarijaloo F, Wokhlu A
Clin Cardiol 2022 Apr;45(4):370-378. Epub 2022 Jan 25 doi: 10.1002/clc.23780. PMID: 35077583Free PMC Article
Mitral E wave deceleration time to peak E velocity ratio and cardiovascular outcome in hypertensive patients during antihypertensive treatment (from the LIFE echo-substudy).
Chinali M, Aurigemma GP, de Simone G, Mishra RK, Gerdts E, Wachtell K, Boman K, Dahlöf B, Devereux RB
Am J Cardiol 2009 Oct 15;104(8):1098-104. doi: 10.1016/j.amjcard.2009.05.063. PMID: 19801032

Recent clinical studies

Etiology

Unfavourable outcomes in patients with heart failure with higher preserved left ventricular ejection fraction.
Ohte N, Kikuchi S, Iwahashi N, Kinugasa Y, Dohi K, Takase H, Masai K, Inoue K, Okumura T, Hachiya K, Kitada S, Seo Y; EASY HFpEF Investigators
Eur Heart J Cardiovasc Imaging 2023 Feb 17;24(3):293-300. doi: 10.1093/ehjci/jeac240. PMID: 36464890
Echocardiographic changes after arteriovenous fistula creation in hemodialysis patients.
Manzur-Pineda K, Martinez L, Alvarez R, Dejman A, Vazquez-Padron RI, Tabbara M, Duque JC
Clin Nephrol 2022 Nov;98(5):229-238. doi: 10.5414/CN110816. PMID: 36168799Free PMC Article
Association of Epicardial Fat with Diastolic and Vascular Functions in Children with Type 1 Diabetes.
Ahmad FA, Metwalley KA, Mohamad IL
Pediatr Cardiol 2022 Jun;43(5):999-1010. Epub 2022 Jan 28 doi: 10.1007/s00246-021-02811-x. PMID: 35088126
E/e' ratio and outcome prediction in hypertrophic cardiomyopathy: the influence of outflow tract obstruction.
Lu DY, Haileselassie B, Ventoulis I, Liu HY, Liang HY, Pozios I, Canepa M, Phillip S, Abraham MR, Abraham T
Eur Heart J Cardiovasc Imaging 2018 Jan 1;19(1):101-107. doi: 10.1093/ehjci/jex134. PMID: 28977350
Is mitral E/E' ratio a reliable predictor of left ventricular diastolic pressures in patients without heart failure?
Previtali M, Chieffo E, Ferrario M, Klersy C
Eur Heart J Cardiovasc Imaging 2012 Jul;13(7):588-95. Epub 2011 Dec 19 doi: 10.1093/ejechocard/jer286. PMID: 22184787

Diagnosis

Unfavourable outcomes in patients with heart failure with higher preserved left ventricular ejection fraction.
Ohte N, Kikuchi S, Iwahashi N, Kinugasa Y, Dohi K, Takase H, Masai K, Inoue K, Okumura T, Hachiya K, Kitada S, Seo Y; EASY HFpEF Investigators
Eur Heart J Cardiovasc Imaging 2023 Feb 17;24(3):293-300. doi: 10.1093/ehjci/jeac240. PMID: 36464890
Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling.
von Jeinsen B, Short MI, Larson MG, Xanthakis V, McManus DD, Benjamin EJ, Mitchell GF, Aragam J, Cheng S, Vasan RS
J Am Soc Echocardiogr 2020 Jan;33(1):72-81.e6. Epub 2019 Oct 14 doi: 10.1016/j.echo.2019.08.001. PMID: 31624026Free PMC Article
E/e' ratio and outcome prediction in hypertrophic cardiomyopathy: the influence of outflow tract obstruction.
Lu DY, Haileselassie B, Ventoulis I, Liu HY, Liang HY, Pozios I, Canepa M, Phillip S, Abraham MR, Abraham T
Eur Heart J Cardiovasc Imaging 2018 Jan 1;19(1):101-107. doi: 10.1093/ehjci/jex134. PMID: 28977350
E/e' Ratio in Patients With Unexplained Dyspnea: Lack of Accuracy in Estimating Left Ventricular Filling Pressure.
Santos M, Rivero J, McCullough SD, West E, Opotowsky AR, Waxman AB, Systrom DM, Shah AM
Circ Heart Fail 2015 Jul;8(4):749-56. Epub 2015 Jun 11 doi: 10.1161/CIRCHEARTFAILURE.115.002161. PMID: 26067855Free PMC Article
Is mitral E/E' ratio a reliable predictor of left ventricular diastolic pressures in patients without heart failure?
Previtali M, Chieffo E, Ferrario M, Klersy C
Eur Heart J Cardiovasc Imaging 2012 Jul;13(7):588-95. Epub 2011 Dec 19 doi: 10.1093/ejechocard/jer286. PMID: 22184787

Therapy

Unfavourable outcomes in patients with heart failure with higher preserved left ventricular ejection fraction.
Ohte N, Kikuchi S, Iwahashi N, Kinugasa Y, Dohi K, Takase H, Masai K, Inoue K, Okumura T, Hachiya K, Kitada S, Seo Y; EASY HFpEF Investigators
Eur Heart J Cardiovasc Imaging 2023 Feb 17;24(3):293-300. doi: 10.1093/ehjci/jeac240. PMID: 36464890
Echocardiographic changes after arteriovenous fistula creation in hemodialysis patients.
Manzur-Pineda K, Martinez L, Alvarez R, Dejman A, Vazquez-Padron RI, Tabbara M, Duque JC
Clin Nephrol 2022 Nov;98(5):229-238. doi: 10.5414/CN110816. PMID: 36168799Free PMC Article
The impact of obesity on left ventricular hypertrophy and diastolic dysfunction in children and adolescents.
Bartkowiak J, Spitzer E, Kurmann R, Zürcher F, Krähenmann P, Garcia-Ruiz V, Mercado J, Ryffel C, Losdat S, Llerena N, Torres P, Lanz J, Stocker M, Ren B, Glöckler M, Pilgrim T
Sci Rep 2021 Jun 22;11(1):13022. doi: 10.1038/s41598-021-92463-x. PMID: 34158575Free PMC Article
Effect of long-term glucocorticoid therapy on cardiac functions in children with congenital adrenal hyperplasia.
Amr NH, Mahmoud RAA, Youssef O, Toaima NN, Elsedfy H
Clin Endocrinol (Oxf) 2021 Feb;94(2):210-218. Epub 2020 Dec 21 doi: 10.1111/cen.14333. PMID: 32946608
The impact of right ventricular dysfunction on the effectiveness of beta-blockers in heart failure with preserved ejection fraction.
Harada D, Asanoi H, Noto T, Takagawa J
J Cardiol 2020 Oct;76(4):325-334. Epub 2020 May 28 doi: 10.1016/j.jjcc.2020.05.001. PMID: 32475652

Prognosis

Echocardiographic changes after arteriovenous fistula creation in hemodialysis patients.
Manzur-Pineda K, Martinez L, Alvarez R, Dejman A, Vazquez-Padron RI, Tabbara M, Duque JC
Clin Nephrol 2022 Nov;98(5):229-238. doi: 10.5414/CN110816. PMID: 36168799Free PMC Article
Doppler-derived haemodynamics performed during admission echocardiography predict in-hospital mortality in cardiac intensive care unit patients.
Jentzer JC, Tabi M, Wiley BM, Lanspa MJ, Anavekar NS, Oh JK
Eur Heart J Acute Cardiovasc Care 2022 Aug 9;11(8):640-650. doi: 10.1093/ehjacc/zuac084. PMID: 35851395
Association of Epicardial Fat with Diastolic and Vascular Functions in Children with Type 1 Diabetes.
Ahmad FA, Metwalley KA, Mohamad IL
Pediatr Cardiol 2022 Jun;43(5):999-1010. Epub 2022 Jan 28 doi: 10.1007/s00246-021-02811-x. PMID: 35088126
E/e' ratio and outcome prediction in hypertrophic cardiomyopathy: the influence of outflow tract obstruction.
Lu DY, Haileselassie B, Ventoulis I, Liu HY, Liang HY, Pozios I, Canepa M, Phillip S, Abraham MR, Abraham T
Eur Heart J Cardiovasc Imaging 2018 Jan 1;19(1):101-107. doi: 10.1093/ehjci/jex134. PMID: 28977350
Is mitral E/E' ratio a reliable predictor of left ventricular diastolic pressures in patients without heart failure?
Previtali M, Chieffo E, Ferrario M, Klersy C
Eur Heart J Cardiovasc Imaging 2012 Jul;13(7):588-95. Epub 2011 Dec 19 doi: 10.1093/ejechocard/jer286. PMID: 22184787

Clinical prediction guides

Echocardiographic changes after arteriovenous fistula creation in hemodialysis patients.
Manzur-Pineda K, Martinez L, Alvarez R, Dejman A, Vazquez-Padron RI, Tabbara M, Duque JC
Clin Nephrol 2022 Nov;98(5):229-238. doi: 10.5414/CN110816. PMID: 36168799Free PMC Article
Association of Epicardial Fat with Diastolic and Vascular Functions in Children with Type 1 Diabetes.
Ahmad FA, Metwalley KA, Mohamad IL
Pediatr Cardiol 2022 Jun;43(5):999-1010. Epub 2022 Jan 28 doi: 10.1007/s00246-021-02811-x. PMID: 35088126
Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling.
von Jeinsen B, Short MI, Larson MG, Xanthakis V, McManus DD, Benjamin EJ, Mitchell GF, Aragam J, Cheng S, Vasan RS
J Am Soc Echocardiogr 2020 Jan;33(1):72-81.e6. Epub 2019 Oct 14 doi: 10.1016/j.echo.2019.08.001. PMID: 31624026Free PMC Article
E/e' ratio and outcome prediction in hypertrophic cardiomyopathy: the influence of outflow tract obstruction.
Lu DY, Haileselassie B, Ventoulis I, Liu HY, Liang HY, Pozios I, Canepa M, Phillip S, Abraham MR, Abraham T
Eur Heart J Cardiovasc Imaging 2018 Jan 1;19(1):101-107. doi: 10.1093/ehjci/jex134. PMID: 28977350
Is mitral E/E' ratio a reliable predictor of left ventricular diastolic pressures in patients without heart failure?
Previtali M, Chieffo E, Ferrario M, Klersy C
Eur Heart J Cardiovasc Imaging 2012 Jul;13(7):588-95. Epub 2011 Dec 19 doi: 10.1093/ejechocard/jer286. PMID: 22184787

Recent systematic reviews

The effect of exercise training and physiotherapy on left and right heart function in heart failure with preserved ejection fraction: a systematic literature review.
Palevičiūtė E, Šimbelytė T, Eichstaedt CA, Benjamin N, Egenlauf B, Grünig E, Čelutkienė J
Heart Fail Rev 2023 Jan;28(1):193-206. Epub 2022 Jul 13 doi: 10.1007/s10741-022-10259-1. PMID: 35831689Free PMC Article

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