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Malignant Cervical Soft Tissue Neoplasm

MedGen UID:
926307
•Concept ID:
C4288775
•
Neoplastic Process

Definition

A rare malignant mesenchymal neoplasm that arises from the cervix. [from NCI]

Professional guidelines

PubMed

DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms.
Yao J, Bergsland E, Aggarwal R, Aparicio A, Beltran H, Crabtree JS, Hann CL, Ibrahim T, Byers LA, Sasano H, Umejiego J, Pavel M
Oncologist 2022 Nov 3;27(11):940-951. doi: 10.1093/oncolo/oyac161. PMID: 35983951Free PMC Article
Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA
J Natl Compr Canc Netw 2022 Jul;20(7):815-833. doi: 10.6004/jnccn.2022.0035. PMID: 35830886Free PMC Article
Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy in postoperative treatment of endometrial and cervical cancer.
Small W Jr, Mell LK, Anderson P, Creutzberg C, De Los Santos J, Gaffney D, Jhingran A, Portelance L, Schefter T, Iyer R, Varia M, Winter K, Mundt AJ
Int J Radiat Oncol Biol Phys 2008 Jun 1;71(2):428-34. Epub 2007 Nov 26 doi: 10.1016/j.ijrobp.2007.09.042. PMID: 18037584Free PMC Article

Recent clinical studies

Etiology

Cutaneous soft tissue sarcomas: survival-related factors.
Gkantaifi A, Diamantis A, Mauri D, Nixon I, Kyriazoglou A, Baloyiannis I, Tsoukalas N, Charalampakis N, Schizas D, Cuccia F, Alongi F, de Mello RA, Iliadis G, Kamposioras K, Mazonakis M, Tolia M
Arch Dermatol Res 2022 Sep;314(7):625-631. Epub 2021 Jul 17 doi: 10.1007/s00403-021-02268-1. PMID: 34272971
Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck.
Baranov E, Hornick JL
Head Neck Pathol 2020 Mar;14(1):43-58. Epub 2020 Jan 16 doi: 10.1007/s12105-019-01104-3. PMID: 31950474Free PMC Article
Vascular Anomalies.
Johnson AB, Richter GT
Clin Perinatol 2018 Dec;45(4):737-749. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.010. PMID: 30396415
Pediatric neurofibrosarcoma.
Neville H, Corpron C, Blakely ML, Andrassy R
J Pediatr Surg 2003 Mar;38(3):343-6; discussion 343-6. doi: 10.1053/jpsu.2003.50105. PMID: 12632346
Lipoblastoma.
Chun YS, Kim WK, Park KW, Lee SC, Jung SE
J Pediatr Surg 2001 Jun;36(6):905-7. doi: 10.1053/jpsu.2001.23969. PMID: 11381423

Diagnosis

Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA
J Natl Compr Canc Netw 2022 Jul;20(7):815-833. doi: 10.6004/jnccn.2022.0035. PMID: 35830886Free PMC Article
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Soft Tissue Tumors.
Jo VY, Demicco EG
Head Neck Pathol 2022 Mar;16(1):87-100. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01425-w. PMID: 35312984Free PMC Article
NCCN Guidelines Insights: Soft Tissue Sarcoma, Version 1.2021.
von Mehren M, Kane JM, Bui MM, Choy E, Connelly M, Dry S, Ganjoo KN, George S, Gonzalez RJ, Heslin MJ, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Meyer C, Pappo AS, Parkes AM, Paz IB, Petersen IA, Poppe M, Riedel RF, Rubin B, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Bergman MA, George GV
J Natl Compr Canc Netw 2020 Dec 2;18(12):1604-1612. doi: 10.6004/jnccn.2020.0058. PMID: 33285515
Soft-tissue sarcoma.
Gilbert NF, Cannon CP, Lin PP, Lewis VO
J Am Acad Orthop Surg 2009 Jan;17(1):40-7. doi: 10.5435/00124635-200901000-00006. PMID: 19136426
Myofibrosarcoma.
Fisher C
Virchows Arch 2004 Sep;445(3):215-23. Epub 2004 Jun 2 doi: 10.1007/s00428-004-1038-9. PMID: 15173943

Therapy

Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study.
Penel N, Bui BN, Bay JO, Cupissol D, Ray-Coquard I, Piperno-Neumann S, Kerbrat P, Fournier C, Taieb S, Jimenez M, Isambert N, Peyrade F, Chevreau C, Bompas E, Brain EG, Blay JY
J Clin Oncol 2008 Nov 10;26(32):5269-74. Epub 2008 Sep 22 doi: 10.1200/JCO.2008.17.3146. PMID: 18809609
Microenvironment-induced cancer metastasis.
Rofstad EK
Int J Radiat Biol 2000 May;76(5):589-605. doi: 10.1080/095530000138259. PMID: 10866281
Soft tissue sarcomas.
Alvegård T
Acta Oncol 1996;35 Suppl 7:117-22. doi: 10.3109/02841869609101671. PMID: 9154103
Docetaxel.
Cortes JE, Pazdur R
J Clin Oncol 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643. PMID: 7595719
Infusion-embolization.
Wallace S, Charnsangavej C, Carrasco CH, Bechtel W
Cancer 1984 Dec 1;54(11 Suppl):2751-65. doi: 10.1002/1097-0142(19841201)54:2+<2751::aid-cncr2820541423>3.0.co;2-5. PMID: 6093984

Prognosis

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Soft Tissue Tumors.
Jo VY, Demicco EG
Head Neck Pathol 2022 Mar;16(1):87-100. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01425-w. PMID: 35312984Free PMC Article
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Angiofibroma of soft tissue: Current status of pathology and genetics.
Nakayama S, Nishio J, Aoki M, Koga K, Nabeshima K, Yamamoto T
Histol Histopathol 2022 Aug;37(8):717-722. Epub 2022 Feb 25 doi: 10.14670/HH-18-444. PMID: 35211945
Cutaneous soft tissue sarcomas: survival-related factors.
Gkantaifi A, Diamantis A, Mauri D, Nixon I, Kyriazoglou A, Baloyiannis I, Tsoukalas N, Charalampakis N, Schizas D, Cuccia F, Alongi F, de Mello RA, Iliadis G, Kamposioras K, Mazonakis M, Tolia M
Arch Dermatol Res 2022 Sep;314(7):625-631. Epub 2021 Jul 17 doi: 10.1007/s00403-021-02268-1. PMID: 34272971
Soft-tissue sarcoma.
Gilbert NF, Cannon CP, Lin PP, Lewis VO
J Am Acad Orthop Surg 2009 Jan;17(1):40-7. doi: 10.5435/00124635-200901000-00006. PMID: 19136426

Clinical prediction guides

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
PET Imaging for Head and Neck Cancers.
Marcus C, Sheikhbahaei S, Shivamurthy VKN, Avey G, Subramaniam RM
Radiol Clin North Am 2021 Sep;59(5):773-788. doi: 10.1016/j.rcl.2021.05.005. PMID: 34392918
Overview of the 8th Edition TNM Classification for Head and Neck Cancer.
Huang SH, O'Sullivan B
Curr Treat Options Oncol 2017 Jul;18(7):40. doi: 10.1007/s11864-017-0484-y. PMID: 28555375
Angiosarcoma.
Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ
Lancet Oncol 2010 Oct;11(10):983-91. Epub 2010 May 25 doi: 10.1016/S1470-2045(10)70023-1. PMID: 20537949
Metallothioneins and cancer.
Eckschlager T, Adam V, Hrabeta J, Figova K, Kizek R
Curr Protein Pept Sci 2009 Aug;10(4):360-75. doi: 10.2174/138920309788922243. PMID: 19689357

Recent systematic reviews

Hyperbaric oxygen therapy for late radiation tissue injury.
Lin ZC, Bennett MH, Hawkins GC, Azzopardi CP, Feldmeier J, Smee R, Milross C
Cochrane Database Syst Rev 2023 Aug 15;8(8):CD005005. doi: 10.1002/14651858.CD005005.pub5. PMID: 37585677Free PMC Article
Mandibular reconstruction in head and neck cancer: which is the gold standard?
Molteni G, Gazzini L, Sacchetto A, Nocini R, Comini LV, Arietti V, Locatello LG, Mannelli G
Eur Arch Otorhinolaryngol 2023 Sep;280(9):3953-3965. Epub 2023 Jun 3 doi: 10.1007/s00405-023-08050-5. PMID: 37269408
Prognostic significance of soft tissue deposits in head and neck squamous cell carcinoma: a systematic review and meta-analysis.
Kaul P, Malhotra M, Arora V, Agarwal N, Singh MP, Garg PK
Int J Oral Maxillofac Surg 2023 Sep;52(9):917-922. Epub 2023 Feb 11 doi: 10.1016/j.ijom.2023.01.014. PMID: 36781359
Oral radiation-induced sarcomas: Systematic review.
de Souza LL, Pontes HAR, Santos-Silva AR, Fernandes LA, Batista LAL, Lopes MA, Khan W, Pontes FSC
Head Neck 2020 Sep;42(9):2660-2668. Epub 2020 Apr 28 doi: 10.1002/hed.26176. PMID: 32343457
Denture use and osteoradionecrosis following radiotherapy for head and neck cancer: A systematic review.
Abed H, Burke M, Scambler S, Scott SE
Gerodontology 2020 Jun;37(2):102-109. Epub 2019 Dec 30 doi: 10.1111/ger.12456. PMID: 31886587

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