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Diffuse Glioma

MedGen UID:
927222
Concept ID:
C4289690
Neoplastic Process

Definition

A glioma that has diffusely infiltrated the surrounding central nervous system tissues. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiffuse Glioma

Professional guidelines

PubMed

van den Bent MJ, Geurts M, French PJ, Smits M, Capper D, Bromberg JEC, Chang SM
Lancet 2023 Oct 28;402(10412):1564-1579. Epub 2023 Sep 19 doi: 10.1016/S0140-6736(23)01054-1. PMID: 37738997
Jiang T, Nam DH, Ram Z, Poon WS, Wang J, Boldbaatar D, Mao Y, Ma W, Mao Q, You Y, Jiang C, Yang X, Kang C, Qiu X, Li W, Li S, Chen L, Li X, Liu Z, Wang W, Bai H, Yao Y, Li S, Wu A, Sai K, Li G, Yao K, Wei X, Liu X, Zhang Z, Dai Y, Lv S, Wang L, Lin Z, Dong J, Xu G, Ma X, Zhang W, Zhang C, Chen B, You G, Wang Y, Wang Y, Bao Z, Yang P, Fan X, Liu X, Zhao Z, Wang Z, Li Y, Wang Z, Li G, Fang S, Li L, Liu Y, Liu S, Shan X, Liu Y, Chai R, Hu H, Chen J, Yan W, Cai J, Wang H, Chen L, Yang Y, Wang Y, Han L, Wang Q; Chinese Glioma Cooperative Group (CGCG); Society for Neuro‐Oncology of China (SNO-China); Chinese Brain Cancer Association (CBCA); Chinese Glioma Genome Atlas (CGGA); Asian Glioma Genome Atlas (AGGA) network
Cancer Lett 2021 Feb 28;499:60-72. Epub 2020 Nov 6 doi: 10.1016/j.canlet.2020.10.050. PMID: 33166616
van Tellingen O, Yetkin-Arik B, de Gooijer MC, Wesseling P, Wurdinger T, de Vries HE
Drug Resist Updat 2015 Mar;19:1-12. Epub 2015 Mar 6 doi: 10.1016/j.drup.2015.02.002. PMID: 25791797

Recent clinical studies

Etiology

Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W
Nature 2021 Apr;592(7854):463-468. Epub 2021 Mar 24 doi: 10.1038/s41586-021-03363-z. PMID: 33762734Free PMC Article
Nicholson JG, Fine HA
Cancer Discov 2021 Mar;11(3):575-590. Epub 2021 Feb 8 doi: 10.1158/2159-8290.CD-20-1474. PMID: 33558264
Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR
Nat Rev Neurol 2019 Jul;15(7):405-417. Epub 2019 Jun 21 doi: 10.1038/s41582-019-0220-2. PMID: 31227792Free PMC Article
Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Carlotti CG Jr, Tirapelli DP, Rao A, Mikkelsen T, Lau CC, Yung WK, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Zheng S, Hess K, Rao G, Meyerson M, Beroukhim R, Cooper L, Akbani R, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH; TCGA Research Network, Noushmehr H, Iavarone A, Verhaak RG
Cell 2016 Jan 28;164(3):550-63. doi: 10.1016/j.cell.2015.12.028. PMID: 26824661Free PMC Article
van Tellingen O, Yetkin-Arik B, de Gooijer MC, Wesseling P, Wurdinger T, de Vries HE
Drug Resist Updat 2015 Mar;19:1-12. Epub 2015 Mar 6 doi: 10.1016/j.drup.2015.02.002. PMID: 25791797

Diagnosis

van den Bent MJ, Geurts M, French PJ, Smits M, Capper D, Bromberg JEC, Chang SM
Lancet 2023 Oct 28;402(10412):1564-1579. Epub 2023 Sep 19 doi: 10.1016/S0140-6736(23)01054-1. PMID: 37738997
Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W
Nature 2021 Apr;592(7854):463-468. Epub 2021 Mar 24 doi: 10.1038/s41586-021-03363-z. PMID: 33762734Free PMC Article
Nicholson JG, Fine HA
Cancer Discov 2021 Mar;11(3):575-590. Epub 2021 Feb 8 doi: 10.1158/2159-8290.CD-20-1474. PMID: 33558264
Slegers RJ, Blumcke I
Acta Neuropathol Commun 2020 Mar 9;8(1):27. doi: 10.1186/s40478-020-00904-x. PMID: 32151273Free PMC Article
Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR
Nat Rev Neurol 2019 Jul;15(7):405-417. Epub 2019 Jun 21 doi: 10.1038/s41582-019-0220-2. PMID: 31227792Free PMC Article

Therapy

Hollon T, Jiang C, Chowdury A, Nasir-Moin M, Kondepudi A, Aabedi A, Adapa A, Al-Holou W, Heth J, Sagher O, Lowenstein P, Castro M, Wadiura LI, Widhalm G, Neuschmelting V, Reinecke D, von Spreckelsen N, Berger MS, Hervey-Jumper SL, Golfinos JG, Snuderl M, Camelo-Piragua S, Freudiger C, Lee H, Orringer DA
Nat Med 2023 Apr;29(4):828-832. Epub 2023 Mar 23 doi: 10.1038/s41591-023-02252-4. PMID: 36959422Free PMC Article
Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W
Nature 2021 Apr;592(7854):463-468. Epub 2021 Mar 24 doi: 10.1038/s41586-021-03363-z. PMID: 33762734Free PMC Article
Jiang T, Nam DH, Ram Z, Poon WS, Wang J, Boldbaatar D, Mao Y, Ma W, Mao Q, You Y, Jiang C, Yang X, Kang C, Qiu X, Li W, Li S, Chen L, Li X, Liu Z, Wang W, Bai H, Yao Y, Li S, Wu A, Sai K, Li G, Yao K, Wei X, Liu X, Zhang Z, Dai Y, Lv S, Wang L, Lin Z, Dong J, Xu G, Ma X, Zhang W, Zhang C, Chen B, You G, Wang Y, Wang Y, Bao Z, Yang P, Fan X, Liu X, Zhao Z, Wang Z, Li Y, Wang Z, Li G, Fang S, Li L, Liu Y, Liu S, Shan X, Liu Y, Chai R, Hu H, Chen J, Yan W, Cai J, Wang H, Chen L, Yang Y, Wang Y, Han L, Wang Q; Chinese Glioma Cooperative Group (CGCG); Society for Neuro‐Oncology of China (SNO-China); Chinese Brain Cancer Association (CBCA); Chinese Glioma Genome Atlas (CGGA); Asian Glioma Genome Atlas (AGGA) network
Cancer Lett 2021 Feb 28;499:60-72. Epub 2020 Nov 6 doi: 10.1016/j.canlet.2020.10.050. PMID: 33166616
Esparragosa I, Díez-Valle R, Tejada S, Gállego Pérez-Larraya J
Presse Med 2018 Nov-Dec;47(11-12 Pt 2):e199-e212. Epub 2018 Oct 29 doi: 10.1016/j.lpm.2018.04.014. PMID: 30385181
van Tellingen O, Yetkin-Arik B, de Gooijer MC, Wesseling P, Wurdinger T, de Vries HE
Drug Resist Updat 2015 Mar;19:1-12. Epub 2015 Mar 6 doi: 10.1016/j.drup.2015.02.002. PMID: 25791797

Prognosis

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W
Nature 2021 Apr;592(7854):463-468. Epub 2021 Mar 24 doi: 10.1038/s41586-021-03363-z. PMID: 33762734Free PMC Article
Nicholson JG, Fine HA
Cancer Discov 2021 Mar;11(3):575-590. Epub 2021 Feb 8 doi: 10.1158/2159-8290.CD-20-1474. PMID: 33558264
Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR
Nat Rev Neurol 2019 Jul;15(7):405-417. Epub 2019 Jun 21 doi: 10.1038/s41582-019-0220-2. PMID: 31227792Free PMC Article
van Tellingen O, Yetkin-Arik B, de Gooijer MC, Wesseling P, Wurdinger T, de Vries HE
Drug Resist Updat 2015 Mar;19:1-12. Epub 2015 Mar 6 doi: 10.1016/j.drup.2015.02.002. PMID: 25791797

Clinical prediction guides

Hollon T, Jiang C, Chowdury A, Nasir-Moin M, Kondepudi A, Aabedi A, Adapa A, Al-Holou W, Heth J, Sagher O, Lowenstein P, Castro M, Wadiura LI, Widhalm G, Neuschmelting V, Reinecke D, von Spreckelsen N, Berger MS, Hervey-Jumper SL, Golfinos JG, Snuderl M, Camelo-Piragua S, Freudiger C, Lee H, Orringer DA
Nat Med 2023 Apr;29(4):828-832. Epub 2023 Mar 23 doi: 10.1038/s41591-023-02252-4. PMID: 36959422Free PMC Article
Mo Z, Xin J, Chai R, Woo PYM, Chan DTM, Wang J
Cancer Biol Med 2022 Nov 1;19(10):1440-59. doi: 10.20892/j.issn.2095-3941.2022.0418. PMID: 36350002Free PMC Article
Krishna S, Hervey-Jumper SL
Adv Biol (Weinh) 2022 Sep;6(9):e2200047. Epub 2022 Jul 8 doi: 10.1002/adbi.202200047. PMID: 35802914Free PMC Article
Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W
Nature 2021 Apr;592(7854):463-468. Epub 2021 Mar 24 doi: 10.1038/s41586-021-03363-z. PMID: 33762734Free PMC Article
Wirsching HG, Weller M
Curr Treat Options Oncol 2016 Oct;17(10):51. doi: 10.1007/s11864-016-0430-4. PMID: 27501915

Recent systematic reviews

Muzyka L, Goff NK, Choudhary N, Koltz MT
Int J Mol Sci 2023 Jun 21;24(13) doi: 10.3390/ijms241310456. PMID: 37445633Free PMC Article
Fauvet C, Villain M, Gatignol P
Neurosurg Rev 2023 Jun 29;46(1):156. doi: 10.1007/s10143-023-02073-6. PMID: 37382692
Halasz LM, Attia A, Bradfield L, Brat DJ, Kirkpatrick JP, Laack NN, Lalani N, Lebow ES, Liu AK, Niemeier HM, Palmer JD, Peters KB, Sheehan J, Thomas RP, Vora SA, Wahl DR, Weiss SE, Yeboa DN, Zhong J, Shih HA
Pract Radiat Oncol 2022 Sep-Oct;12(5):370-386. Epub 2022 May 31 doi: 10.1016/j.prro.2022.05.004. PMID: 35902341
Lasocki A, Anjari M, Ӧrs Kokurcan S, Thust SC
Neuroradiology 2021 Mar;63(3):353-362. Epub 2020 Aug 25 doi: 10.1007/s00234-020-02532-7. PMID: 32840682
Fan X, Li Y, Shan X, You G, Wu Z, Li Z, Qiao H, Jiang T
Seizure 2018 Jul;59:16-23. Epub 2018 Apr 25 doi: 10.1016/j.seizure.2018.04.018. PMID: 29727741

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