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Colonization

MedGen UID:
927299
•Concept ID:
C4289767
•
Finding

Definition

The presence of microorganisms (not contamination) on a body surface, including the skin and mucosal surfaces (e.g., respiratory, gastrointestinal, and urogenital tracts). Colonization implies the lack of signs or symptoms of infection but often precedes infection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColonization

Professional guidelines

PubMed

Acne Vulgaris: Diagnosis and Treatment.
Oge' LK, Broussard A, Marshall MD
Am Fam Physician 2019 Oct 15;100(8):475-484. PMID: 31613567
Pathogenesis and clinical management of Helicobacter pylori gastric infection.
de Brito BB, da Silva FAF, Soares AS, Pereira VA, Santos MLC, Sampaio MM, Neves PHM, de Melo FF
World J Gastroenterol 2019 Oct 7;25(37):5578-5589. doi: 10.3748/wjg.v25.i37.5578. PMID: 31602159Free PMC Article
Diagnosis and treatment of acne.
Titus S, Hodge J
Am Fam Physician 2012 Oct 15;86(8):734-40. PMID: 23062156

Recent clinical studies

Etiology

Clinical Risk Factors and Microbiological and Intestinal Characteristics of Carbapenemase-Producing Enterobacteriaceae Colonization and Subsequent Infection.
Yuan W, Xu J, Guo L, Chen Y, Gu J, Zhang H, Yang C, Yang Q, Deng S, Zhang L, Deng Q, Wang Z, Ling B, Deng D
Microbiol Spectr 2022 Dec 21;10(6):e0190621. Epub 2022 Nov 29 doi: 10.1128/spectrum.01906-21. PMID: 36445086Free PMC Article
Supplementation of Probiotics in Pregnant Women Targeting Group B Streptococcus Colonization: A Systematic Review and Meta-Analysis.
Menichini D, Chiossi G, Monari F, De Seta F, Facchinetti F
Nutrients 2022 Oct 27;14(21) doi: 10.3390/nu14214520. PMID: 36364782Free PMC Article
Burn Wound Colonization, Infection, and Sepsis.
Ladhani HA, Yowler CJ, Claridge JA
Surg Infect (Larchmt) 2021 Feb;22(1):44-48. Epub 2020 Oct 20 doi: 10.1089/sur.2020.346. PMID: 33085576
Understanding Clostridium difficile Colonization.
Crobach MJT, Vernon JJ, Loo VG, Kong LY, Péchiné S, Wilcox MH, Kuijper EJ
Clin Microbiol Rev 2018 Apr;31(2) Epub 2018 Mar 14 doi: 10.1128/CMR.00021-17. PMID: 29540433Free PMC Article
Streptococcus pyogenes adhesion and colonization.
Brouwer S, Barnett TC, Rivera-Hernandez T, Rohde M, Walker MJ
FEBS Lett 2016 Nov;590(21):3739-3757. Epub 2016 Jul 1 doi: 10.1002/1873-3468.12254. PMID: 27312939

Diagnosis

Microbiological diagnosis of catheter-related infections.
Aldea Mansilla C, Martínez-Alarcón J, Gracia Ahufinger I, Guembe Ramírez M
Enferm Infecc Microbiol Clin (Engl Ed) 2019 Dec;37(10):668-672. Epub 2018 Sep 13 doi: 10.1016/j.eimc.2018.07.009. PMID: 30220518
Maternal Colonization With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses.
Russell NJ, Seale AC, O'Driscoll M, O'Sullivan C, Bianchi-Jassir F, Gonzalez-Guarin J, Lawn JE, Baker CJ, Bartlett L, Cutland C, Gravett MG, Heath PT, Le Doare K, Madhi SA, Rubens CE, Schrag S, Sobanjo-Ter Meulen A, Vekemans J, Saha SK, Ip M; GBS Maternal Colonization Investigator Group
Clin Infect Dis 2017 Nov 6;65(suppl_2):S100-S111. doi: 10.1093/cid/cix658. PMID: 29117327Free PMC Article
Postoperative fungal infections.
Eggimann P, Pittet D
Surg Infect (Larchmt) 2006;7 Suppl 2:S53-6. doi: 10.1089/sur.2006.7.s2-53. PMID: 16895507
Botulism.
Sobel J
Clin Infect Dis 2005 Oct 15;41(8):1167-73. Epub 2005 Aug 29 doi: 10.1086/444507. PMID: 16163636
Candiduria.
Kauffman CA
Clin Infect Dis 2005 Sep 15;41 Suppl 6:S371-6. doi: 10.1086/430918. PMID: 16108001

Therapy

Acceptability and safety of the menstrual cup: A systematic review of the literature.
Arenas-Gallo C, Ramírez-Rocha G, González-Hakspiel L, Merlano-Alcendra C, Palomino-Suárez D, Rueda-Espinel S
Rev Colomb Obstet Ginecol 2020 Jun;71(2):163-177. doi: 10.18597/rcog.3425. PMID: 32770872
Management and Prevention of Central Venous Catheter-Related Infections in the ICU.
Buetti N, Timsit JF
Semin Respir Crit Care Med 2019 Aug;40(4):508-523. Epub 2019 Oct 4 doi: 10.1055/s-0039-1693705. PMID: 31585477
The pros, cons, and many unknowns of probiotics.
Suez J, Zmora N, Segal E, Elinav E
Nat Med 2019 May;25(5):716-729. Epub 2019 May 6 doi: 10.1038/s41591-019-0439-x. PMID: 31061539
A Review of Combination Antimicrobial Therapy for Enterococcus faecalis Bloodstream Infections and Infective Endocarditis.
Beganovic M, Luther MK, Rice LB, Arias CA, Rybak MJ, LaPlante KL
Clin Infect Dis 2018 Jul 2;67(2):303-309. doi: 10.1093/cid/ciy064. PMID: 29390132Free PMC Article
Vancomycin-resistant enterococci.
Gin AS, Zhanel GG
Ann Pharmacother 1996 Jun;30(6):615-24. doi: 10.1177/106002809603000610. PMID: 8792949

Prognosis

Effect of a Multi-Strain Probiotic on the Incidence and Severity of Necrotizing Enterocolitis and Feeding Intolerances in Preterm Neonates.
Sowden M, van Weissenbruch MM, Bulabula ANH, van Wyk L, Twisk J, van Niekerk E
Nutrients 2022 Aug 12;14(16) doi: 10.3390/nu14163305. PMID: 36014810Free PMC Article
Central venous catheter-related bloodstream infection and colonization: the impact of insertion site and distribution of multidrug-resistant pathogens.
Pitiriga V, Kanellopoulos P, Bakalis I, Kampos E, Sagris I, Saroglou G, Tsakris A
Antimicrob Resist Infect Control 2020 Dec 1;9(1):189. doi: 10.1186/s13756-020-00851-1. PMID: 33261661Free PMC Article
Brain metastasization of breast cancer.
Custódio-Santos T, Videira M, Brito MA
Biochim Biophys Acta Rev Cancer 2017 Aug;1868(1):132-147. Epub 2017 Mar 21 doi: 10.1016/j.bbcan.2017.03.004. PMID: 28341420
Early Onset Sepsis.
Johnson K, Messier S
S D Med 2016 Jan;69(1):29-33. PMID: 26882580
Neonatal invasive candidiasis.
Stronati M, Decembrino L
Minerva Pediatr 2006 Dec;58(6):537-49. PMID: 17093376

Clinical prediction guides

Impact of environmental hygiene interventions on healthcare-associated infections and patient colonization: a systematic review.
Peters A, Schmid MN, Parneix P, Lebowitz D, de Kraker M, Sauser J, Zingg W, Pittet D
Antimicrob Resist Infect Control 2022 Feb 19;11(1):38. doi: 10.1186/s13756-022-01075-1. PMID: 35183259Free PMC Article
Tackling the recurrence of Clostridium difficile infection.
Petrosillo N
Med Mal Infect 2018 Feb;48(1):18-22. Epub 2018 Jan 12 doi: 10.1016/j.medmal.2017.10.007. PMID: 29336928
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article
Predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal swab PCR assay for MRSA pneumonia.
Dangerfield B, Chung A, Webb B, Seville MT
Antimicrob Agents Chemother 2014;58(2):859-64. Epub 2013 Nov 25 doi: 10.1128/AAC.01805-13. PMID: 24277023Free PMC Article
A bedside scoring system ("Candida score") for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization.
León C, Ruiz-Santana S, Saavedra P, Almirante B, Nolla-Salas J, Alvarez-Lerma F, Garnacho-Montero J, León MA; EPCAN Study Group
Crit Care Med 2006 Mar;34(3):730-7. doi: 10.1097/01.CCM.0000202208.37364.7D. PMID: 16505659

Recent systematic reviews

Supplementation of Probiotics in Pregnant Women Targeting Group B Streptococcus Colonization: A Systematic Review and Meta-Analysis.
Menichini D, Chiossi G, Monari F, De Seta F, Facchinetti F
Nutrients 2022 Oct 27;14(21) doi: 10.3390/nu14214520. PMID: 36364782Free PMC Article
Impact of environmental hygiene interventions on healthcare-associated infections and patient colonization: a systematic review.
Peters A, Schmid MN, Parneix P, Lebowitz D, de Kraker M, Sauser J, Zingg W, Pittet D
Antimicrob Resist Infect Control 2022 Feb 19;11(1):38. doi: 10.1186/s13756-022-01075-1. PMID: 35183259Free PMC Article
Maternal Colonization With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses.
Russell NJ, Seale AC, O'Driscoll M, O'Sullivan C, Bianchi-Jassir F, Gonzalez-Guarin J, Lawn JE, Baker CJ, Bartlett L, Cutland C, Gravett MG, Heath PT, Le Doare K, Madhi SA, Rubens CE, Schrag S, Sobanjo-Ter Meulen A, Vekemans J, Saha SK, Ip M; GBS Maternal Colonization Investigator Group
Clin Infect Dis 2017 Nov 6;65(suppl_2):S100-S111. doi: 10.1093/cid/cix658. PMID: 29117327Free PMC Article
The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life: a systematic review.
Rutayisire E, Huang K, Liu Y, Tao F
BMC Gastroenterol 2016 Jul 30;16(1):86. doi: 10.1186/s12876-016-0498-0. PMID: 27475754Free PMC Article
Diagnosis and treatment of Clostridium difficile in adults: a systematic review.
Bagdasarian N, Rao K, Malani PN
JAMA 2015 Jan 27;313(4):398-408. doi: 10.1001/jama.2014.17103. PMID: 25626036Free PMC Article

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