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Colon Adenoma with Severe Dysplasia

MedGen UID:
927300
Concept ID:
C4289768
Neoplastic Process

Definition

An adenoma that arises from the colon. It is characterized by the presence of severe epithelial dysplasia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColon Adenoma with Severe Dysplasia

Professional guidelines

PubMed

Canzonieri C, Centenara L, Ornati F, Pagella F, Matti E, Alvisi C, Danesino C, Perego M, Olivieri C
Genet Med 2014 Jan;16(1):3-10. Epub 2013 May 30 doi: 10.1038/gim.2013.62. PMID: 23722869
Itzkowitz SH, Harpaz N
Gastroenterology 2004 May;126(6):1634-48. doi: 10.1053/j.gastro.2004.03.025. PMID: 15168373
Rainsbury RM, Lallemand RC
Ann R Coll Surg Engl 1988 Mar;70(2):80-4. PMID: 3408165Free PMC Article

Recent clinical studies

Etiology

DelSignore M, Jeong T, Denmark G, Feldman D, Shih A, Zukerberg L, Chung DC
Gastrointest Endosc 2023 Jan;97(1):25-34.e6. Epub 2022 Sep 14 doi: 10.1016/j.gie.2022.09.002. PMID: 36113625
Qari YA
Niger J Clin Pract 2020 Aug;23(8):1048-1053. doi: 10.4103/njcp.njcp_490_19. PMID: 32788480
Sourrouille I, Lefèvre JH, Shields C, Colas C, Bellanger J, Desaint B, Paye F, Tiret E, Parc Y
Dis Colon Rectum 2017 Nov;60(11):1137-1146. doi: 10.1097/DCR.0000000000000903. PMID: 28991077
Itzkowitz SH, Harpaz N
Gastroenterology 2004 May;126(6):1634-48. doi: 10.1053/j.gastro.2004.03.025. PMID: 15168373
Kim EC, Lance P
Gastroenterol Clin North Am 1997 Mar;26(1):1-17. doi: 10.1016/s0889-8553(05)70280-6. PMID: 9119435

Diagnosis

DelSignore M, Jeong T, Denmark G, Feldman D, Shih A, Zukerberg L, Chung DC
Gastrointest Endosc 2023 Jan;97(1):25-34.e6. Epub 2022 Sep 14 doi: 10.1016/j.gie.2022.09.002. PMID: 36113625
Lee KY, Lee J, Park YY, Oh ST
BMC Gastroenterol 2021 Feb 27;21(1):91. doi: 10.1186/s12876-021-01672-1. PMID: 33639847Free PMC Article
Sourrouille I, Lefèvre JH, Shields C, Colas C, Bellanger J, Desaint B, Paye F, Tiret E, Parc Y
Dis Colon Rectum 2017 Nov;60(11):1137-1146. doi: 10.1097/DCR.0000000000000903. PMID: 28991077
Itzkowitz SH, Harpaz N
Gastroenterology 2004 May;126(6):1634-48. doi: 10.1053/j.gastro.2004.03.025. PMID: 15168373
Kim EC, Lance P
Gastroenterol Clin North Am 1997 Mar;26(1):1-17. doi: 10.1016/s0889-8553(05)70280-6. PMID: 9119435

Therapy

Nakaoka M, Chiba H, Kobayashi M, Okada N, Arimoto J, Tachikawa J, Ashikari K, Kuwabara H
Dig Dis 2024;42(1):31-40. Epub 2023 Nov 15 doi: 10.1159/000534968. PMID: 37967542Free PMC Article
Castaño Llano R, Molina Meneses SP, Puerta JD, Escobar RM, Salazar Ochoa S, Puerta JE, Barreiro-de Acosta M
Gastroenterol Hepatol 2023 Jan;46(1):39-47. Epub 2022 May 20 doi: 10.1016/j.gastrohep.2022.05.005. PMID: 35605822
Ryu HS, Yu CS, Kim YI, Lee JL, Kim CW, Yoon YS, Park IJ, Lim SB, Kim JC
World J Gastroenterol 2022 Aug 14;28(30):4152-4162. doi: 10.3748/wjg.v28.i30.4152. PMID: 36157110Free PMC Article
Terhaar Sive Droste JS, Tuynman JB, Van Dullemen HM, Mulder CJ
Scand J Gastroenterol Suppl 2006;(243):158-64. doi: 10.1080/00365520600664284. PMID: 16782636
Itzkowitz SH, Harpaz N
Gastroenterology 2004 May;126(6):1634-48. doi: 10.1053/j.gastro.2004.03.025. PMID: 15168373

Prognosis

DelSignore M, Jeong T, Denmark G, Feldman D, Shih A, Zukerberg L, Chung DC
Gastrointest Endosc 2023 Jan;97(1):25-34.e6. Epub 2022 Sep 14 doi: 10.1016/j.gie.2022.09.002. PMID: 36113625
Bains L, Lal P, Vindal A, Singh M
World J Surg Oncol 2019 Jun 25;17(1):109. doi: 10.1186/s12957-019-1650-4. PMID: 31238922Free PMC Article
Sourrouille I, Lefèvre JH, Shields C, Colas C, Bellanger J, Desaint B, Paye F, Tiret E, Parc Y
Dis Colon Rectum 2017 Nov;60(11):1137-1146. doi: 10.1097/DCR.0000000000000903. PMID: 28991077
Herszényi L, Barabás L, Miheller P, Tulassay Z
Dig Dis 2015;33(1):52-7. Epub 2014 Dec 17 doi: 10.1159/000368447. PMID: 25531497
Day DW
Scand J Gastroenterol Suppl 1984;104:99-107. PMID: 6597553

Clinical prediction guides

Castaño Llano R, Molina Meneses SP, Puerta JD, Escobar RM, Salazar Ochoa S, Puerta JE, Barreiro-de Acosta M
Gastroenterol Hepatol 2023 Jan;46(1):39-47. Epub 2022 May 20 doi: 10.1016/j.gastrohep.2022.05.005. PMID: 35605822
Ryu HS, Yu CS, Kim YI, Lee JL, Kim CW, Yoon YS, Park IJ, Lim SB, Kim JC
World J Gastroenterol 2022 Aug 14;28(30):4152-4162. doi: 10.3748/wjg.v28.i30.4152. PMID: 36157110Free PMC Article
Lee KY, Lee J, Park YY, Oh ST
BMC Gastroenterol 2021 Feb 27;21(1):91. doi: 10.1186/s12876-021-01672-1. PMID: 33639847Free PMC Article
Sourrouille I, Lefèvre JH, Shields C, Colas C, Bellanger J, Desaint B, Paye F, Tiret E, Parc Y
Dis Colon Rectum 2017 Nov;60(11):1137-1146. doi: 10.1097/DCR.0000000000000903. PMID: 28991077
Terhaar Sive Droste JS, Tuynman JB, Van Dullemen HM, Mulder CJ
Scand J Gastroenterol Suppl 2006;(243):158-64. doi: 10.1080/00365520600664284. PMID: 16782636

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