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Cervical Malignant Peripheral Nerve Sheath Tumor

MedGen UID:
927346
•Concept ID:
C4289814
•
Neoplastic Process

Definition

A rare malignant neoplasm with nerve sheath differentiation arising from the cervix. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervical Malignant Peripheral Nerve Sheath Tumor

Professional guidelines

PubMed

Malignant peripheral nerve sheath tumors of the head and neck: Demographics, clinicopathologic features, management, and treatment outcomes.
Arshi A, Tajudeen BA, St John M
Oral Oncol 2015 Dec;51(12):1088-94. Epub 2015 Oct 9 doi: 10.1016/j.oraloncology.2015.08.012. PMID: 26442813
Malignant peripheral nerve sheath tumors of the head and neck: management of 10 cases and literature review.
Minovi A, Basten O, Hunter B, Draf W, Bockmühl U
Head Neck 2007 May;29(5):439-45. doi: 10.1002/hed.20537. PMID: 17163467
Primary parapharyngeal space tumors in a Mexican cancer center.
Luna-Ortiz K, Navarrete-Alemán JE, Granados-García M, Herrera-Gómez A
Otolaryngol Head Neck Surg 2005 Apr;132(4):587-91. doi: 10.1016/j.otohns.2005.01.013. PMID: 15806051

Recent clinical studies

Etiology

Primary malignant peripheral nerve sheath tumors of bone: a clinicopathologic reappraisal of 8 cases.
Gambarotti M, Righi A, Sbaraglia M, Cocchi S, Benini S, Magagnoli G, Frisoni T, Palmerini E, Picci P, Dei Tos AP
Hum Pathol 2022 Apr;122:92-102. Epub 2022 Feb 15 doi: 10.1016/j.humpath.2022.02.003. PMID: 35176251
Peripheral neck nerve tumor: A 73-case study and literature review.
Boumaza K, Michel G, Salaud C, Bossard C, Espitalier F, Malard O
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Nov;136(6):455-460. Epub 2019 Sep 16 doi: 10.1016/j.anorl.2019.09.005. PMID: 31537489
Malignant peripheral nerve sheath tumors: Analysis of the national cancer database.
Mowery A, Clayburgh D
Oral Oncol 2019 Nov;98:13-19. Epub 2019 Sep 13 doi: 10.1016/j.oraloncology.2019.09.010. PMID: 31525622
A brief report of plexiform neurofibroma.
Khajavi M, Khoshsirat S, Ahangarnazari L, Majdinasab N
Curr Probl Cancer 2018 Mar-Apr;42(2):256-260. Epub 2018 Jan 10 doi: 10.1016/j.currproblcancer.2018.01.007. PMID: 29449010
Pediatric neurofibrosarcoma.
Neville H, Corpron C, Blakely ML, Andrassy R
J Pediatr Surg 2003 Mar;38(3):343-6; discussion 343-6. doi: 10.1053/jpsu.2003.50105. PMID: 12632346

Diagnosis

Peripheral Nerve Sheath Tumors of Head and Neck: Imaging-Based Review of World Health Organization Classification.
Abdel Razek AAK, Gamaleldin OA, Elsebaie NA
J Comput Assist Tomogr 2020 Nov/Dec;44(6):928-940. doi: 10.1097/RCT.0000000000001109. PMID: 33196600
Peripheral neck nerve tumor: A 73-case study and literature review.
Boumaza K, Michel G, Salaud C, Bossard C, Espitalier F, Malard O
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Nov;136(6):455-460. Epub 2019 Sep 16 doi: 10.1016/j.anorl.2019.09.005. PMID: 31537489
Intradural Extramedullary Spinal Neoplasms: Radiologic-Pathologic Correlation.
Koeller KK, Shih RY
Radiographics 2019 Mar-Apr;39(2):468-490. doi: 10.1148/rg.2019180200. PMID: 30844353
A brief report of plexiform neurofibroma.
Khajavi M, Khoshsirat S, Ahangarnazari L, Majdinasab N
Curr Probl Cancer 2018 Mar-Apr;42(2):256-260. Epub 2018 Jan 10 doi: 10.1016/j.currproblcancer.2018.01.007. PMID: 29449010
Pediatric neurofibrosarcoma.
Neville H, Corpron C, Blakely ML, Andrassy R
J Pediatr Surg 2003 Mar;38(3):343-6; discussion 343-6. doi: 10.1053/jpsu.2003.50105. PMID: 12632346

Therapy

Malignant peripheral nerve sheath tumor with analysis of various prognostic factors: A single-institutional experience.
Sharma MR, Puj KS, Salunke AA, Pandya SJ, Gandhi JS, Parikh AR
J Cancer Res Ther 2021 Jan-Mar;17(1):106-113. doi: 10.4103/jcrt.JCRT_854_19. PMID: 33723140
Neurological outcomes and surgical complications in 221 spinal nerve sheath tumors.
Safaee MM, Lyon R, Barbaro NM, Chou D, Mummaneni PV, Weinstein PR, Chin CT, Tihan T, Ames CP
J Neurosurg Spine 2017 Jan;26(1):103-111. Epub 2016 Jul 29 doi: 10.3171/2016.5.SPINE15974. PMID: 27472744
Radiotherapy-induced malignant peripheral nerve sheath tumor of the cauda equina.
Amin A, Saifuddin A, Flanagan A, Patterson D, Lehovsky J
Spine (Phila Pa 1976) 2004 Nov 1;29(21):E506-9. doi: 10.1097/01.brs.0000143168.87295.ca. PMID: 15507791
Radiation-induced malignant and atypical peripheral nerve sheath tumors.
Foley KM, Woodruff JM, Ellis FT, Posner JB
Ann Neurol 1980 Apr;7(4):311-8. doi: 10.1002/ana.410070405. PMID: 7377756
Neurofibrosarcoma.
Hiranandani LH, Hiranandani NL, Hiranandani GK
J Laryngol Otol 1967 Dec;81(12):1381-93. doi: 10.1017/s0022215100068377. PMID: 6078229

Prognosis

Incidence and prognosis of distant metastasis in malignant peripheral nerve sheath tumors.
Xu Y, Xu G, Liu Z, Duan J, Lin Y, Zhu J, Baklaushev VP, Chekhonin VP, Peltzer K, Wang G, Wang X, Zhang C
Acta Neurochir (Wien) 2021 Feb;163(2):521-529. Epub 2020 Nov 21 doi: 10.1007/s00701-020-04647-5. PMID: 33219865
Peripheral Nerve Sheath Tumors of Head and Neck: Imaging-Based Review of World Health Organization Classification.
Abdel Razek AAK, Gamaleldin OA, Elsebaie NA
J Comput Assist Tomogr 2020 Nov/Dec;44(6):928-940. doi: 10.1097/RCT.0000000000001109. PMID: 33196600
Prognosis and risk factors for malignant peripheral nerve sheath tumor: a systematic review and meta-analysis.
Cai Z, Tang X, Liang H, Yang R, Yan T, Guo W
World J Surg Oncol 2020 Sep 30;18(1):257. doi: 10.1186/s12957-020-02036-x. PMID: 32998743Free PMC Article
Peripheral neck nerve tumor: A 73-case study and literature review.
Boumaza K, Michel G, Salaud C, Bossard C, Espitalier F, Malard O
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Nov;136(6):455-460. Epub 2019 Sep 16 doi: 10.1016/j.anorl.2019.09.005. PMID: 31537489
Pediatric neurofibrosarcoma.
Neville H, Corpron C, Blakely ML, Andrassy R
J Pediatr Surg 2003 Mar;38(3):343-6; discussion 343-6. doi: 10.1053/jpsu.2003.50105. PMID: 12632346

Clinical prediction guides

Incidence and prognosis of distant metastasis in malignant peripheral nerve sheath tumors.
Xu Y, Xu G, Liu Z, Duan J, Lin Y, Zhu J, Baklaushev VP, Chekhonin VP, Peltzer K, Wang G, Wang X, Zhang C
Acta Neurochir (Wien) 2021 Feb;163(2):521-529. Epub 2020 Nov 21 doi: 10.1007/s00701-020-04647-5. PMID: 33219865
Peripheral Nerve Sheath Tumors of Head and Neck: Imaging-Based Review of World Health Organization Classification.
Abdel Razek AAK, Gamaleldin OA, Elsebaie NA
J Comput Assist Tomogr 2020 Nov/Dec;44(6):928-940. doi: 10.1097/RCT.0000000000001109. PMID: 33196600
Peripheral neck nerve tumor: A 73-case study and literature review.
Boumaza K, Michel G, Salaud C, Bossard C, Espitalier F, Malard O
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Nov;136(6):455-460. Epub 2019 Sep 16 doi: 10.1016/j.anorl.2019.09.005. PMID: 31537489
Malignant peripheral nerve sheath tumors: Analysis of the national cancer database.
Mowery A, Clayburgh D
Oral Oncol 2019 Nov;98:13-19. Epub 2019 Sep 13 doi: 10.1016/j.oraloncology.2019.09.010. PMID: 31525622
Malignant peripheral nerve sheath tumors (MPNST): the Mayo Clinic experience.
Stucky CC, Johnson KN, Gray RJ, Pockaj BA, Ocal IT, Rose PS, Wasif N
Ann Surg Oncol 2012 Mar;19(3):878-85. Epub 2011 Aug 23 doi: 10.1245/s10434-011-1978-7. PMID: 21861229

Recent systematic reviews

Prognosis and risk factors for malignant peripheral nerve sheath tumor: a systematic review and meta-analysis.
Cai Z, Tang X, Liang H, Yang R, Yan T, Guo W
World J Surg Oncol 2020 Sep 30;18(1):257. doi: 10.1186/s12957-020-02036-x. PMID: 32998743Free PMC Article
Malignant peripheral nerve sheath tumors of the eighth cranial nerve arising without prior irradiation.
Carlson ML, Jacob JT, Habermann EB, Glasgow AE, Raghunathan A, Link MJ
J Neurosurg 2016 Nov;125(5):1120-1129. Epub 2016 Jan 8 doi: 10.3171/2015.7.JNS151056. PMID: 26745487

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