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Adult intestinal botulism

MedGen UID:
Concept ID:
Disease or Syndrome
Synonyms: Adult infection of intestine caused by Clostridium botulinum; Adult Intestinal Botulism; adult intestinal botulism; adult intestinal colonisation botulism; Adult intestinal colonization botulism; adult intestinal colonization botulism; adult intestinal toxaemia botulism; Adult intestinal toxemia botulism; adult intestinal toxemia botulism; Adult intestinal toxin-mediated botulism; adult intestinal toxin-mediated botulism; Infant-like botulism; infant-like botulism; intestinal botulism of adults
SNOMED CT: Adult intestinal botulism (1156793005); Adult infection of intestine caused by Clostridium botulinum (1156793005)
Monarch Initiative: MONDO:0015806
Orphanet: ORPHA178487


A very rare form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis caused by botulinum neurotoxins (BoNTs), and is due to intestinal colonization by <i>Clostridium botulinum</i> leading to toxin-mediated infection with toxemia. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult intestinal botulism

Professional guidelines


Rao AK, Sobel J, Chatham-Stephens K, Luquez C
MMWR Recomm Rep 2021 May 7;70(2):1-30. doi: 10.15585/mmwr.rr7002a1. PMID: 33956777Free PMC Article
Chalk CH, Benstead TJ, Pound JD, Keezer MR
Cochrane Database Syst Rev 2019 Apr 17;4(4):CD008123. doi: 10.1002/14651858.CD008123.pub4. PMID: 30993666Free PMC Article
Brook I
Rev Neurol Dis 2006 Fall;3(4):182-9. PMID: 17224901

Recent clinical studies


Yutani M, Matsumura T, Fujinaga Y
Microbiol Immunol 2021 Oct;65(10):432-437. Epub 2021 Sep 8 doi: 10.1111/1348-0421.12928. PMID: 34219270


Harris RA, Anniballi F, Austin JW
Toxins (Basel) 2020 Jan 24;12(2) doi: 10.3390/toxins12020081. PMID: 31991691Free PMC Article

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