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Malignant hypertension

MedGen UID:
9374
Concept ID:
C0020540
Disease or Syndrome
Synonyms: Hypertension, Malignant; Malignant Hypertension
SNOMED CT: Malignant hypertension (70272006)
 
Monarch Initiative: MONDO:0006846

Definition

Severe hypertension that is characterized by rapid onset of extremely high blood pressure. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Leisring J, Brodsky SV, Parikh SV
Arthritis Rheumatol 2024 Feb;76(2):153-165. Epub 2023 Nov 30 doi: 10.1002/art.42681. PMID: 37610060
Kulkarni S, Glover M, Kapil V, Abrams SML, Partridge S, McCormack T, Sever P, Delles C, Wilkinson IB
J Hum Hypertens 2023 Oct;37(10):863-879. Epub 2022 Nov 22 doi: 10.1038/s41371-022-00776-9. PMID: 36418425Free PMC Article
Lewek J, Bielecka-Dąbrowa A, Maciejewski M, Banach M
Expert Opin Pharmacother 2020 Jul;21(10):1189-1192. Epub 2020 Feb 26 doi: 10.1080/14656566.2020.1732923. PMID: 32100590

Curated

UK NICE guideline (NG133), Hypertension in pregnancy: diagnosis and management, 2023

Recent clinical studies

Etiology

Boulestreau R, Śpiewak M, Januszewicz A, Kreutz R, Guzik TJ, Januszewicz M, Muiesan ML, Persu A, Sarafidis P, Volpe M, Zaleska-Żmijewska A, van den Born BH, Messerli FH
J Am Coll Cardiol 2024 Apr 30;83(17):1688-1701. doi: 10.1016/j.jacc.2024.02.037. PMID: 38658108
Leisring J, Brodsky SV, Parikh SV
Arthritis Rheumatol 2024 Feb;76(2):153-165. Epub 2023 Nov 30 doi: 10.1002/art.42681. PMID: 37610060
Werion A, Storms P, Zizi Y, Beguin C, Bernards J, Cambier JF, Dahan K, Dierickx D, Godefroid N, Hilbert P, Lambert C, Levtchenko E, Meyskens T, Poiré X, van den Heuvel L, Claes KJ, Morelle J; UCLouvain TMA/HUS Network and KU Leuven TMA/HUS Network
Clin J Am Soc Nephrol 2023 Jul 1;18(7):881-891. Epub 2023 Apr 21 doi: 10.2215/CJN.0000000000000182. PMID: 37094330Free PMC Article
Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Bayer G, von Tokarski F, Thoreau B, Bauvois A, Barbet C, Cloarec S, Mérieau E, Lachot S, Garot D, Bernard L, Gyan E, Perrotin F, Pouplard C, Maillot F, Gatault P, Sautenet B, Rusch E, Buchler M, Vigneau C, Fakhouri F, Halimi JM
Clin J Am Soc Nephrol 2019 Apr 5;14(4):557-566. Epub 2019 Mar 12 doi: 10.2215/CJN.11470918. PMID: 30862697Free PMC Article

Diagnosis

Leisring J, Brodsky SV, Parikh SV
Arthritis Rheumatol 2024 Feb;76(2):153-165. Epub 2023 Nov 30 doi: 10.1002/art.42681. PMID: 37610060
Kulkarni S, Glover M, Kapil V, Abrams SML, Partridge S, McCormack T, Sever P, Delles C, Wilkinson IB
J Hum Hypertens 2023 Oct;37(10):863-879. Epub 2022 Nov 22 doi: 10.1038/s41371-022-00776-9. PMID: 36418425Free PMC Article
Cavero T, Auñón P, Caravaca-Fontán F, Trujillo H, Arjona E, Morales E, Guillén E, Blasco M, Rabasco C, Espinosa M, Blanco M, Rodríguez-Magariños C, Cao M, Ávila A, Huerta A, Rubio E, Cabello V, Barros X, Goicoechea de Jorge E, Rodríguez de Córdoba S, Praga M
Nephrol Dial Transplant 2023 May 4;38(5):1217-1226. doi: 10.1093/ndt/gfac248. PMID: 36002030
Boulestreau R, van den Born BH, Lip GYH, Gupta A
J Am Heart Assoc 2022 Apr 5;11(7):e023397. Epub 2022 Mar 15 doi: 10.1161/JAHA.121.023397. PMID: 35289189Free PMC Article
Sharma D, Farahbakhsh N, Shastri S, Sharma P
J Matern Fetal Neonatal Med 2017 Mar;30(5):540-550. Epub 2016 May 5 doi: 10.1080/14767058.2016.1177816. PMID: 27072362

Therapy

Boulestreau R, Śpiewak M, Januszewicz A, Kreutz R, Guzik TJ, Januszewicz M, Muiesan ML, Persu A, Sarafidis P, Volpe M, Zaleska-Żmijewska A, van den Born BH, Messerli FH
J Am Coll Cardiol 2024 Apr 30;83(17):1688-1701. doi: 10.1016/j.jacc.2024.02.037. PMID: 38658108
Siddiqi TJ, Usman MS, Rashid AM, Javaid SS, Ahmed A, Clark D 3rd, Flack JM, Shimbo D, Choi E, Jones DW, Hall ME
J Am Heart Assoc 2023 Jul 18;12(14):e029355. Epub 2023 Jul 8 doi: 10.1161/JAHA.122.029355. PMID: 37421281Free PMC Article
Jolly H, Freel EM, Isles C
Postgrad Med J 2023 May 19;99(1169):119-126. doi: 10.1136/postgradmedj-2021-140899. PMID: 37222066
Kulkarni S, Glover M, Kapil V, Abrams SML, Partridge S, McCormack T, Sever P, Delles C, Wilkinson IB
J Hum Hypertens 2023 Oct;37(10):863-879. Epub 2022 Nov 22 doi: 10.1038/s41371-022-00776-9. PMID: 36418425Free PMC Article
Boulestreau R, van den Born BH, Lip GYH, Gupta A
J Am Heart Assoc 2022 Apr 5;11(7):e023397. Epub 2022 Mar 15 doi: 10.1161/JAHA.121.023397. PMID: 35289189Free PMC Article

Prognosis

Boulestreau R, Śpiewak M, Januszewicz A, Kreutz R, Guzik TJ, Januszewicz M, Muiesan ML, Persu A, Sarafidis P, Volpe M, Zaleska-Żmijewska A, van den Born BH, Messerli FH
J Am Coll Cardiol 2024 Apr 30;83(17):1688-1701. doi: 10.1016/j.jacc.2024.02.037. PMID: 38658108
Siddiqi TJ, Usman MS, Rashid AM, Javaid SS, Ahmed A, Clark D 3rd, Flack JM, Shimbo D, Choi E, Jones DW, Hall ME
J Am Heart Assoc 2023 Jul 18;12(14):e029355. Epub 2023 Jul 8 doi: 10.1161/JAHA.122.029355. PMID: 37421281Free PMC Article
Boulestreau R, van den Born BH, Lip GYH, Gupta A
J Am Heart Assoc 2022 Apr 5;11(7):e023397. Epub 2022 Mar 15 doi: 10.1161/JAHA.121.023397. PMID: 35289189Free PMC Article
Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Bayer G, von Tokarski F, Thoreau B, Bauvois A, Barbet C, Cloarec S, Mérieau E, Lachot S, Garot D, Bernard L, Gyan E, Perrotin F, Pouplard C, Maillot F, Gatault P, Sautenet B, Rusch E, Buchler M, Vigneau C, Fakhouri F, Halimi JM
Clin J Am Soc Nephrol 2019 Apr 5;14(4):557-566. Epub 2019 Mar 12 doi: 10.2215/CJN.11470918. PMID: 30862697Free PMC Article

Clinical prediction guides

Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Bayer G, von Tokarski F, Thoreau B, Bauvois A, Barbet C, Cloarec S, Mérieau E, Lachot S, Garot D, Bernard L, Gyan E, Perrotin F, Pouplard C, Maillot F, Gatault P, Sautenet B, Rusch E, Buchler M, Vigneau C, Fakhouri F, Halimi JM
Clin J Am Soc Nephrol 2019 Apr 5;14(4):557-566. Epub 2019 Mar 12 doi: 10.2215/CJN.11470918. PMID: 30862697Free PMC Article
de Azevedo FVA, Maia DG, de Carvalho JF, Rodrigues CEM
Rheumatol Int 2018 Oct;38(10):1777-1789. Epub 2018 May 5 doi: 10.1007/s00296-018-4040-2. PMID: 29730854
Shantsila A, Lip GYH
Am J Hypertens 2017 Jun 1;30(6):543-549. doi: 10.1093/ajh/hpx008. PMID: 28200072
Meyrier A
Nephrol Dial Transplant 2015 Nov;30(11):1833-41. Epub 2014 Dec 8 doi: 10.1093/ndt/gfu366. PMID: 25488894

Recent systematic reviews

Siddiqi TJ, Usman MS, Rashid AM, Javaid SS, Ahmed A, Clark D 3rd, Flack JM, Shimbo D, Choi E, Jones DW, Hall ME
J Am Heart Assoc 2023 Jul 18;12(14):e029355. Epub 2023 Jul 8 doi: 10.1161/JAHA.122.029355. PMID: 37421281Free PMC Article
Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Dai XM, Yin MM, Liu Y, Ma LL, Ying J, Jiang LD
Chin Med J (Engl) 2020 Apr 20;133(8):975-981. doi: 10.1097/CM9.0000000000000704. PMID: 32187045Free PMC Article
Usai MV, Torsello G, Donas KP
J Endovasc Ther 2015 Jun;22(3):396-400. Epub 2015 Apr 15 doi: 10.1177/1526602815581161. PMID: 25878021

Supplemental Content

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    Clinical resources

    Practice guidelines

    • PubMed
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE guideline (NG133), Hypertension in pregnancy: diagnosis and management, 2023

    Consumer resources

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