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Hypochondriasis

MedGen UID:
9382
•Concept ID:
C0020604
•
Mental or Behavioral Dysfunction
Synonyms: Hypochondriacal Neuroses; Hypochondriacal Neurosis; Neurosis, Hypochondriacal
SNOMED CT: Hypochondriasis (18193002); Hypochondriacal neurosis (18193002); Hypochondria (18193002)
 
Monarch Initiative: MONDO:0001596

Definition

A somatoform disorder in which an individual is preoccupied with having a serious illness despite not having been given a corroborating diagnosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypochondriasis

Professional guidelines

PubMed

Recent Advances in the Understanding and Treatment of Health Anxiety.
Tyrer P
Curr Psychiatry Rep 2018 Jun 22;20(7):49. doi: 10.1007/s11920-018-0912-0. PMID: 29931576
Hypochondriasis--recognition and management.
Riaz T, Kazi AN
J Pak Med Assoc 2011 Mar;61(3):302-3. PMID: 21465956
Somatization. Diagnosis and management.
Noyes R Jr, Holt CS, Kathol RG
Arch Fam Med 1995 Sep;4(9):790-5. doi: 10.1001/archfami.4.9.790. PMID: 7647946

Recent clinical studies

Etiology

Recent Advances in the Understanding and Treatment of Health Anxiety.
Tyrer P
Curr Psychiatry Rep 2018 Jun 22;20(7):49. doi: 10.1007/s11920-018-0912-0. PMID: 29931576
Avoidance in hypochondriasis.
Doherty-Torstrick ER, Walton KE, Barsky AJ, Fallon BA
J Psychosom Res 2016 Oct;89:46-52. Epub 2016 Jul 19 doi: 10.1016/j.jpsychores.2016.07.010. PMID: 27663110
Medically unexplained symptoms, somatisation disorder and hypochondriasis: course and prognosis. A systematic review.
olde Hartman TC, Borghuis MS, Lucassen PL, van de Laar FA, Speckens AE, van Weel C
J Psychosom Res 2009 May;66(5):363-77. Epub 2008 Dec 16 doi: 10.1016/j.jpsychores.2008.09.018. PMID: 19379952
Somatoform disorders.
Oyama O, Paltoo C, Greengold J
Am Fam Physician 2007 Nov 1;76(9):1333-8. PMID: 18019877
Transient hypochondriasis.
Barsky AJ, Wyshak G, Klerman GL
Arch Gen Psychiatry 1990 Aug;47(8):746-52. doi: 10.1001/archpsyc.1990.01810200054007. PMID: 2378545

Diagnosis

Recent Advances in the Understanding and Treatment of Health Anxiety.
Tyrer P
Curr Psychiatry Rep 2018 Jun 22;20(7):49. doi: 10.1007/s11920-018-0912-0. PMID: 29931576
Hypochondria.
Bound F
Lancet 2006 Jan 14;367(9505):105. doi: 10.1016/S0140-6736(06)67948-8. PMID: 16413863
Headache.
Brown SJ
Fam Pract Manag 2005 Feb;12(2):68. PMID: 15779285
Hypochondriasis and somatization.
Kellner R
JAMA 1987 Nov 20;258(19):2718-22. PMID: 3312664
Hypochondriasis.
Brown HN, Vaillant GE
Arch Intern Med 1981 May;141(6):723-6. PMID: 7235779

Therapy

Postinfection Irritable Bowel Syndrome.
Ghoshal UC
Gut Liver 2022 May 15;16(3):331-340. doi: 10.5009/gnl210208. PMID: 34789582Free PMC Article
Side Effect Profiles of Selective Serotonin Reuptake Inhibitors: A Cross-Sectional Study in a Naturalistic Setting.
Anagha K, Shihabudheen P, Uvais NA
Prim Care Companion CNS Disord 2021 Jul 29;23(4) doi: 10.4088/PCC.20m02747. PMID: 34324797
Cyberchondria in the age of COVID-19.
Jokic-Begic N, Lauri Korajlija A, Mikac U
PLoS One 2020;15(12):e0243704. Epub 2020 Dec 17 doi: 10.1371/journal.pone.0243704. PMID: 33332400Free PMC Article
Recent Advances in the Understanding and Treatment of Health Anxiety.
Tyrer P
Curr Psychiatry Rep 2018 Jun 22;20(7):49. doi: 10.1007/s11920-018-0912-0. PMID: 29931576
Using antipsychotic agents in older patients.
Alexopoulos GS, Streim J, Carpenter D, Docherty JP; Expert Consensus Panel for Using Antipsychotic Drugs in Older Patients
J Clin Psychiatry 2004;65 Suppl 2:5-99; discussion 100-102; quiz 103-4. PMID: 14994733

Prognosis

Comparison of bipolar disorder type II and major depressive disorder.
Miola A, Tondo L, Pinna M, Contu M, Baldessarini RJ
J Affect Disord 2023 Feb 15;323:204-212. Epub 2022 Nov 21 doi: 10.1016/j.jad.2022.11.039. PMID: 36410453
Somatic symptom disorder: a diagnostic dilemma.
Dunphy L, Penna M, El-Kafsi J
BMJ Case Rep 2019 Nov 25;12(11) doi: 10.1136/bcr-2019-231550. PMID: 31772129Free PMC Article
Medically unexplained symptoms, somatisation disorder and hypochondriasis: course and prognosis. A systematic review.
olde Hartman TC, Borghuis MS, Lucassen PL, van de Laar FA, Speckens AE, van Weel C
J Psychosom Res 2009 May;66(5):363-77. Epub 2008 Dec 16 doi: 10.1016/j.jpsychores.2008.09.018. PMID: 19379952
Hypochondriasis and somatization.
Kellner R
JAMA 1987 Nov 20;258(19):2718-22. PMID: 3312664
Hypochondriacal states.
Kenyon FE
Br J Psychiatry 1976 Jul;129:1-14. doi: 10.1192/bjp.129.1.1. PMID: 779913

Clinical prediction guides

Hypochondriasis and Personality Traits of Patients with Chronic Plaque Psoriasis.
Gisondi P, Geat D, Ferrazzi A, Bellinato F, Girolomoni G
Dermatology 2022;238(2):276-282. Epub 2021 Jul 29 doi: 10.1159/000517018. PMID: 34325430
Emotion dysregulation in hypochondriasis and depression.
Bailer J, Witthöft M, Erkic M, Mier D
Clin Psychol Psychother 2017 Nov;24(6):1254-1262. Epub 2017 Apr 26 doi: 10.1002/cpp.2089. PMID: 28444850
Medically unexplained symptoms, somatisation disorder and hypochondriasis: course and prognosis. A systematic review.
olde Hartman TC, Borghuis MS, Lucassen PL, van de Laar FA, Speckens AE, van Weel C
J Psychosom Res 2009 May;66(5):363-77. Epub 2008 Dec 16 doi: 10.1016/j.jpsychores.2008.09.018. PMID: 19379952
Transient hypochondriasis.
Barsky AJ, Wyshak G, Klerman GL
Arch Gen Psychiatry 1990 Aug;47(8):746-52. doi: 10.1001/archpsyc.1990.01810200054007. PMID: 2378545
Agoraphobia in men.
Hafner RJ
Aust N Z J Psychiatry 1981 Sep;15(3):243-9. doi: 10.3109/00048678109159442. PMID: 6949583

Recent systematic reviews

Personality in Chronic Headache: A Systematic Review with Meta-Analysis.
Bottiroli S, Renzi A, Ballante E, De Icco R, Sances G, Tanzilli A, Vecchi T, Tassorelli C, Galli F
Pain Res Manag 2023;2023:6685372. Epub 2023 Aug 28 doi: 10.1155/2023/6685372. PMID: 37671122Free PMC Article
Conceptualizations of Cyberchondria and Relations to the Anxiety Spectrum: Systematic Review and Meta-analysis.
Schenkel SK, Jungmann SM, Gropalis M, Witthöft M
J Med Internet Res 2021 Nov 18;23(11):e27835. doi: 10.2196/27835. PMID: 34792473Free PMC Article
Death anxiety and its association with hypochondriasis and medically unexplained symptoms: A systematic review.
Aan de Stegge BM, Tak LM, Rosmalen JGM, Oude Voshaar RC
J Psychosom Res 2018 Dec;115:58-65. Epub 2018 Oct 10 doi: 10.1016/j.jpsychores.2018.10.002. PMID: 30470318
Medically unexplained symptoms, somatisation disorder and hypochondriasis: course and prognosis. A systematic review.
olde Hartman TC, Borghuis MS, Lucassen PL, van de Laar FA, Speckens AE, van Weel C
J Psychosom Res 2009 May;66(5):363-77. Epub 2008 Dec 16 doi: 10.1016/j.jpsychores.2008.09.018. PMID: 19379952
Psychotherapies for hypochondriasis.
Thomson AB, Page LA
Cochrane Database Syst Rev 2007 Oct 17;2007(4):CD006520. doi: 10.1002/14651858.CD006520.pub2. PMID: 17943915Free PMC Article

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