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Alveolar bone loss around teeth

MedGen UID:
939930
Concept ID:
C4315963
Finding
Synonym: Bone loss around teeth
 
HPO: HP:0410027

Definition

A decrease in the amount of alveolar bone around the root of a tooth. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlveolar bone loss around teeth

Conditions with this feature

Ehlers-Danlos syndrome, periodontal type 1
MedGen UID:
1642148
Concept ID:
C4551499
Disease or Syndrome
Periodontal Ehlers-Danlos syndrome (pEDS) is characterized by distinct oral manifestations. Periodontal tissue breakdown beginning in the teens results in premature loss of teeth. Lack of attached gingiva and thin and fragile gums lead to gingival recession. Connective tissue abnormalities of pEDS typically include easy bruising, pretibial plaques, distal joint hypermobility, hoarse voice, and less commonly manifestations such as organ or vessel rupture. Since the first descriptions of pEDS in the 1970s, 148 individuals have been reported in the literature; however, future in-depth descriptions of non-oral manifestations in newly diagnosed individuals with a molecularly confirmed diagnosis of pEDS will be important to further define the clinical features.

Professional guidelines

PubMed

Quirynen M, Siawasch S, Temmerman A, Cortellini S, Dhondt R, Teughels W, Castro AB
Periodontol 2000 2023 Oct;93(1):254-269. Epub 2023 Oct 16 doi: 10.1111/prd.12526. PMID: 37845802
Burdurlu MÇ, Dagasan VÇ, Tunç O, Güler N
Quintessence Int 2021;52(2):112-121. doi: 10.3290/j.qi.a45264. PMID: 33433077
Frizzera F, Oliveira GJPL, Shibli JA, Moraes KC, Marcantonio EB, Marcantonio Junior E
Braz Oral Res 2019;33(suppl 1):e073. Epub 2019 Sep 30 doi: 10.1590/1807-3107bor-2019.vol33.0073. PMID: 31576957

Recent clinical studies

Etiology

Al-Sosowa AA, Alhajj MN, Abdulghani EA, Al-Moraissi EA, Zheng H, Pang Y, Wang J
Int Dent J 2022 Oct;72(5):634-640. Epub 2022 Jun 25 doi: 10.1016/j.identj.2022.03.003. PMID: 35760735Free PMC Article
de Molon RS, Rossa C Jr, Thurlings RM, Cirelli JA, Koenders MI
Int J Mol Sci 2019 Sep 13;20(18) doi: 10.3390/ijms20184541. PMID: 31540277Free PMC Article
de Molon RS, Park CH, Jin Q, Sugai J, Cirelli JA
Microsc Res Tech 2018 Dec;81(12):1412-1421. Epub 2018 Oct 23 doi: 10.1002/jemt.23101. PMID: 30351474
Levin L, Kessler-Baruch O
N Y State Dent J 2013 Aug-Sep;79(5):53-9. PMID: 24245464
Tarnow DP, Cho SC, Wallace SS
J Periodontol 2000 Apr;71(4):546-9. doi: 10.1902/jop.2000.71.4.546. PMID: 10807116

Diagnosis

Weng Y, Wang H, Li L, Feng Y, Xu S, Wang Z
Redox Biol 2021 Apr;40:101849. Epub 2020 Dec 28 doi: 10.1016/j.redox.2020.101849. PMID: 33486152Free PMC Article
Lin PL, Huang PY, Huang PW
Comput Methods Programs Biomed 2017 Sep;148:1-11. Epub 2017 Jun 24 doi: 10.1016/j.cmpb.2017.06.012. PMID: 28774432
Piau C, Arvieux C, Bonnaure-Mallet M, Jolivet-Gougeon A
Int J Antimicrob Agents 2013 Jun;41(6):509-15. Epub 2013 May 1 doi: 10.1016/j.ijantimicag.2013.03.001. PMID: 23642766
Nahm KY, Kang JH, Moon SC, Choi YS, Kook YA, Kim SH, Huang J
Dentomaxillofac Radiol 2012 Sep;41(6):481-8. Epub 2011 Dec 19 doi: 10.1259/dmfr/30845402. PMID: 22184474Free PMC Article
Sánchez-Gárces MA, Gay-Escoda C
Med Oral Patol Oral Cir Bucal 2004;9 Suppl:69-74; 63-9. PMID: 15580138

Therapy

Frizzera F, Oliveira GJPL, Shibli JA, Moraes KC, Marcantonio EB, Marcantonio Junior E
Braz Oral Res 2019;33(suppl 1):e073. Epub 2019 Sep 30 doi: 10.1590/1807-3107bor-2019.vol33.0073. PMID: 31576957
de Molon RS, Park CH, Jin Q, Sugai J, Cirelli JA
Microsc Res Tech 2018 Dec;81(12):1412-1421. Epub 2018 Oct 23 doi: 10.1002/jemt.23101. PMID: 30351474
Levin L, Kessler-Baruch O
N Y State Dent J 2013 Aug-Sep;79(5):53-9. PMID: 24245464
Sánchez-Gárces MA, Gay-Escoda C
Med Oral Patol Oral Cir Bucal 2004;9 Suppl:69-74; 63-9. PMID: 15580138
Tarnow DP, Cho SC, Wallace SS
J Periodontol 2000 Apr;71(4):546-9. doi: 10.1902/jop.2000.71.4.546. PMID: 10807116

Prognosis

Shukri NMM, Duraisamy R, Balasubramaniam A, Ganapathy D
J Long Term Eff Med Implants 2023;33(2):1-14. doi: 10.1615/JLongTermEffMedImplants.2022041096. PMID: 36734922
Frizzera F, Oliveira GJPL, Shibli JA, Moraes KC, Marcantonio EB, Marcantonio Junior E
Braz Oral Res 2019;33(suppl 1):e073. Epub 2019 Sep 30 doi: 10.1590/1807-3107bor-2019.vol33.0073. PMID: 31576957
Marchesan J, Girnary MS, Jing L, Miao MZ, Zhang S, Sun L, Morelli T, Schoenfisch MH, Inohara N, Offenbacher S, Jiao Y
Nat Protoc 2018 Oct;13(10):2247-2267. doi: 10.1038/s41596-018-0035-4. PMID: 30218100Free PMC Article
Kinaia BM, Shah M, Neely AL, Goodis HE
J Periodontol 2014 Nov;85(11):1537-48. Epub 2014 May 2 doi: 10.1902/jop.2014.130722. PMID: 24794689
Tarnow DP, Cho SC, Wallace SS
J Periodontol 2000 Apr;71(4):546-9. doi: 10.1902/jop.2000.71.4.546. PMID: 10807116

Clinical prediction guides

AlAhmari F, Preethanath RS, Divakar DD, Ali D
Int Dent J 2023 Jun;73(3):443-448. Epub 2022 Dec 1 doi: 10.1016/j.identj.2022.11.019. PMID: 36642571Free PMC Article
Frizzera F, Oliveira GJPL, Shibli JA, Moraes KC, Marcantonio EB, Marcantonio Junior E
Braz Oral Res 2019;33(suppl 1):e073. Epub 2019 Sep 30 doi: 10.1590/1807-3107bor-2019.vol33.0073. PMID: 31576957
de Molon RS, Rossa C Jr, Thurlings RM, Cirelli JA, Koenders MI
Int J Mol Sci 2019 Sep 13;20(18) doi: 10.3390/ijms20184541. PMID: 31540277Free PMC Article
de Molon RS, Park CH, Jin Q, Sugai J, Cirelli JA
Microsc Res Tech 2018 Dec;81(12):1412-1421. Epub 2018 Oct 23 doi: 10.1002/jemt.23101. PMID: 30351474
Marchesan J, Girnary MS, Jing L, Miao MZ, Zhang S, Sun L, Morelli T, Schoenfisch MH, Inohara N, Offenbacher S, Jiao Y
Nat Protoc 2018 Oct;13(10):2247-2267. doi: 10.1038/s41596-018-0035-4. PMID: 30218100Free PMC Article

Recent systematic reviews

Furquim CP, Kumagai RY, Bustillos-Torrez W, Meza-Mauricio J, Tanaka CJ, Santana V, Retamal-Valdes B, Shibli JA
Tissue Eng Part C Methods 2022 Mar;28(3):104-112. doi: 10.1089/ten.TEC.2022.0022. PMID: 35172636
Ahmed N, Arshad S, Basheer SN, Karobari MI, Marya A, Marya CM, Taneja P, Messina P, Yean CY, Scardina GA
Int J Environ Res Public Health 2021 Oct 20;18(21) doi: 10.3390/ijerph182111003. PMID: 34769523Free PMC Article
Mohadeb JV, Somar M, He H
Dent Traumatol 2016 Aug;32(4):255-63. Epub 2015 Dec 10 doi: 10.1111/edt.12247. PMID: 26663218
Kinaia BM, Shah M, Neely AL, Goodis HE
J Periodontol 2014 Nov;85(11):1537-48. Epub 2014 May 2 doi: 10.1902/jop.2014.130722. PMID: 24794689
Firme CT, Vettore MV, Melo M, Vidigal GM Jr
Int J Oral Maxillofac Implants 2014 Jan-Feb;29(1):79-87. doi: 10.11607/jomi.3316. PMID: 24451857

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