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Intestinal polyp

MedGen UID:
9526
•Concept ID:
C0021846
•
Anatomical Abnormality
Synonym: Intestinal polyp (disease)
SNOMED CT: Intestinal polyp (254588001); Polyp of intestine (254588001); Bowel polyp (254588001)
 
HPO: HP:0005266
Monarch Initiative: MONDO:0005288

Definition

A discrete abnormal tissue mass that protrudes into the lumen of the intestine and is attached to the intestinal wall either by a stalk, pedunculus, or a broad base. [from HPO]

Professional guidelines

PubMed

Combined analysis of serum SAP and PRSS2 for the differential diagnosis of CD and UC.
Wang W, Wu L, Wu X, Li K, Li T, Xu B, Liu W
Clin Chim Acta 2021 Mar;514:8-14. Epub 2020 Dec 15 doi: 10.1016/j.cca.2020.12.014. PMID: 33333044
Evaluation of preventive and therapeutic activity of novel non-steroidal anti-inflammatory drug, CG100649, in colon cancer: Increased expression of TNF-related apoptosis-inducing ligand receptors enhance the apoptotic response to combination treatment with TRAIL.
Woo JK, Kang JH, Jang YS, Ro S, Cho JM, Kim HM, Lee SJ, Oh SH
Oncol Rep 2015 Apr;33(4):1947-55. Epub 2015 Feb 10 doi: 10.3892/or.2015.3793. PMID: 25672292
Targeting cyclooxygenase-2 and the epidermal growth factor receptor for the prevention and treatment of intestinal cancer.
Buchanan FG, Holla V, Katkuri S, Matta P, DuBois RN
Cancer Res 2007 Oct 1;67(19):9380-8. doi: 10.1158/0008-5472.CAN-07-0710. PMID: 17909047

Recent clinical studies

Etiology

Factors Associated with Intestinal Polyp Recurrence after Electroresection.
Jin J, Yan B, Yang S, du M
J Coll Physicians Surg Pak 2023 Jun;33(6):633-637. doi: 10.29271/jcpsp.2023.06.633. PMID: 37300257
Comparison of Concordance of Peptic Ulcer Disease, Non-Adenomatous Intestinal Polyp, and Gallstone Disease in Korean Monozygotic and Dizygotic Twins: A Cross-Sectional Study.
Choi HG, Kim SY, Lim H, Kim JH, Kim JH, Cho SJ, Nam ES, Min KW, Park HY, Kim NY, Hong S, Choi Y, Kang HS, Kwon MJ
Int J Environ Res Public Health 2022 Oct 4;19(19) doi: 10.3390/ijerph191912708. PMID: 36232007Free PMC Article
Factors Affecting Adenoma Risk Level in Patients with Intestinal Polyp and Association Analysis.
Dai Y, Chen W, Xu X, Chen J, Mo W, Chen Y, Xu S
J Healthc Eng 2022;2022:9479563. Epub 2022 Jan 15 doi: 10.1155/2022/9479563. PMID: 35075394Free PMC Article
Genome-wide DNA methylation profiling and gut flora analysis in intestinal polyps patients.
Liu L, Chen Y, Liu T, Yu J, Ma L, Wu H
Eur J Gastroenterol Hepatol 2021 Aug 1;33(8):1071-1081. doi: 10.1097/MEG.0000000000002181. PMID: 34213504
Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Apc-deficient mice.
Mutoh M, Niho N, Wakabayashi K
Biol Chem 2006 Apr;387(4):381-5. doi: 10.1515/BC.2006.051. PMID: 16606335

Diagnosis

Artificial intelligence in intestinal polyp and colorectal cancer prediction.
Sharma A, Kumar R, Yadav G, Garg P
Cancer Lett 2023 Jul 1;565:216238. Epub 2023 May 19 doi: 10.1016/j.canlet.2023.216238. PMID: 37211068
MFA-Net: Multiple Feature Association Network for medical image segmentation.
Li Z, Zhang N, Gong H, Qiu R, Zhang W
Comput Biol Med 2023 May;158:106834. Epub 2023 Mar 28 doi: 10.1016/j.compbiomed.2023.106834. PMID: 37003067
SIL-Net: A Semi-Isotropic L-shaped network for dermoscopic image segmentation.
Zhang Z, Jiang Y, Qiao H, Wang M, Yan W, Chen J
Comput Biol Med 2022 Nov;150:106146. Epub 2022 Sep 27 doi: 10.1016/j.compbiomed.2022.106146. PMID: 36228460
Factors Affecting Adenoma Risk Level in Patients with Intestinal Polyp and Association Analysis.
Dai Y, Chen W, Xu X, Chen J, Mo W, Chen Y, Xu S
J Healthc Eng 2022;2022:9479563. Epub 2022 Jan 15 doi: 10.1155/2022/9479563. PMID: 35075394Free PMC Article
Combined analysis of serum SAP and PRSS2 for the differential diagnosis of CD and UC.
Wang W, Wu L, Wu X, Li K, Li T, Xu B, Liu W
Clin Chim Acta 2021 Mar;514:8-14. Epub 2020 Dec 15 doi: 10.1016/j.cca.2020.12.014. PMID: 33333044

Therapy

Artificial intelligence in intestinal polyp and colorectal cancer prediction.
Sharma A, Kumar R, Yadav G, Garg P
Cancer Lett 2023 Jul 1;565:216238. Epub 2023 May 19 doi: 10.1016/j.canlet.2023.216238. PMID: 37211068
Artesunate inhibits intestinal tumorigenesis through inhibiting wnt signaling.
Hamoya T, Fujii G, Iizumi Y, Narita T, Komiya M, Matsuzawa Y, Miki K, Kondo T, Kishimoto S, Watanabe K, Wakabayashi K, Sakai T, Toshima J, Mutoh M
Carcinogenesis 2021 Feb 11;42(1):148-158. doi: 10.1093/carcin/bgaa084. PMID: 32710739
Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Apc-deficient mice.
Mutoh M, Niho N, Wakabayashi K
Biol Chem 2006 Apr;387(4):381-5. doi: 10.1515/BC.2006.051. PMID: 16606335
Prevention of colorectal cancer through the use of COX-2 selective inhibitors.
Peek RM Jr
Cancer Chemother Pharmacol 2004 Sep;54 Suppl 1:S50-6. doi: 10.1007/s00280-004-0887-x. PMID: 15309515
COX selectivity and animal models for colon cancer.
Oshima M, Taketo MM
Curr Pharm Des 2002;8(12):1021-34. doi: 10.2174/1381612023394953. PMID: 11945149

Prognosis

Artificial intelligence in intestinal polyp and colorectal cancer prediction.
Sharma A, Kumar R, Yadav G, Garg P
Cancer Lett 2023 Jul 1;565:216238. Epub 2023 May 19 doi: 10.1016/j.canlet.2023.216238. PMID: 37211068
Massive intussusception caused by a solitary Peutz-Jeghers type hamartomatous polyp.
Kalliakmanis V, Perysinakis I, Koutsouvas K, Karras P, Margaris E, Angelakis C
Ann R Coll Surg Engl 2018 Apr;100(4):e91-e93. Epub 2018 Feb 27 doi: 10.1308/rcsann.2018.0019. PMID: 29484932Free PMC Article
Olfactomedin 4 expression and functions in innate immunity, inflammation, and cancer.
Liu W, Rodgers GP
Cancer Metastasis Rev 2016 Jun;35(2):201-12. doi: 10.1007/s10555-016-9624-2. PMID: 27178440
Circulating cell-free DNA in serum as a biomarker for diagnosis and prognostic prediction of colorectal cancer.
Hao TB, Shi W, Shen XJ, Qi J, Wu XH, Wu Y, Tang YY, Ju SQ
Br J Cancer 2014 Oct 14;111(8):1482-9. Epub 2014 Aug 26 doi: 10.1038/bjc.2014.470. PMID: 25157833Free PMC Article
Alu-based cell-free DNA: a potential complementary biomarker for diagnosis of colorectal cancer.
Qi J, Qian C, Shi W, Wu X, Jing R, Zhang L, Wang Z, Ju S
Clin Biochem 2013 Jan;46(1-2):64-9. Epub 2012 Sep 10 doi: 10.1016/j.clinbiochem.2012.08.026. PMID: 22975639

Clinical prediction guides

Factors Associated with Intestinal Polyp Recurrence after Electroresection.
Jin J, Yan B, Yang S, du M
J Coll Physicians Surg Pak 2023 Jun;33(6):633-637. doi: 10.29271/jcpsp.2023.06.633. PMID: 37300257
Artificial intelligence in intestinal polyp and colorectal cancer prediction.
Sharma A, Kumar R, Yadav G, Garg P
Cancer Lett 2023 Jul 1;565:216238. Epub 2023 May 19 doi: 10.1016/j.canlet.2023.216238. PMID: 37211068
PRAPNet: A Parallel Residual Atrous Pyramid Network for Polyp Segmentation.
Han J, Xu C, An Z, Qian K, Tan W, Wang D, Fang Q
Sensors (Basel) 2022 Jun 21;22(13) doi: 10.3390/s22134658. PMID: 35808154Free PMC Article
Alu-based cell-free DNA: a potential complementary biomarker for diagnosis of colorectal cancer.
Qi J, Qian C, Shi W, Wu X, Jing R, Zhang L, Wang Z, Ju S
Clin Biochem 2013 Jan;46(1-2):64-9. Epub 2012 Sep 10 doi: 10.1016/j.clinbiochem.2012.08.026. PMID: 22975639
Prevention of colorectal cancer through the use of COX-2 selective inhibitors.
Peek RM Jr
Cancer Chemother Pharmacol 2004 Sep;54 Suppl 1:S50-6. doi: 10.1007/s00280-004-0887-x. PMID: 15309515

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