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Miller Fisher syndrome

MedGen UID:
95994
Concept ID:
C0393799
Disease or Syndrome
Synonyms: Fisher Syndrome; Guillain Barre Syndrome, Miller Fisher Variant; Guillain-Barre Syndrome, Miller Fisher Variant; Miller Fisher Syndrome; Miller Fisher Variant of Guillain Barre Syndrome; Miller-Fisher Syndrome; Ophthalmoplegia, Ataxia and Areflexia Syndrome; Syndrome, Fisher; Syndrome, Miller Fisher; Syndrome, Miller-Fisher
SNOMED CT: Fisher syndrome (1767005); Fisher's syndrome (1767005); Ophthalmoplegia, ataxia, areflexia syndrome (1767005); Miller-Fisher variant of Guillain-Barre syndrome (1767005); Miller-Fisher syndrome (1767005)
Modes of inheritance:
Non-Mendelian inheritance
MedGen UID:
109109
Concept ID:
C0600599
Genetic Function
Source: Orphanet
A mode of inheritance that depends on a mixture of major and minor genetic determinants possibly together with environmental factors. Diseases inherited in this manner are termed complex diseases.
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0005851
Orphanet: ORPHA98919

Definition

Miller-Fisher syndrome (MFS) is a rare cranial nerve variant of Guillain-Barré syndrome (GBS; see this term). [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMiller Fisher syndrome
Follow this link to review classifications for Miller Fisher syndrome in Orphanet.

Professional guidelines

PubMed

Lonati D, Schicchi A, Crevani M, Buscaglia E, Scaravaggi G, Maida F, Cirronis M, Petrolini VM, Locatelli CA
Toxins (Basel) 2020 Aug 7;12(8) doi: 10.3390/toxins12080509. PMID: 32784744Free PMC Article
Tan CY, Razali SNO, Goh KJ, Shahrizaila N
J Peripher Nerv Syst 2020 Sep;25(3):256-264. Epub 2020 Jun 29 doi: 10.1111/jns.12398. PMID: 32511817
van Doorn PA
Presse Med 2013 Jun;42(6 Pt 2):e193-201. Epub 2013 Apr 28 doi: 10.1016/j.lpm.2013.02.328. PMID: 23628447

Recent clinical studies

Etiology

Ariño H, Heartshorne R, Michael BD, Nicholson TR, Vincent A, Pollak TA, Vogrig A
J Neurol 2022 Jun;269(6):2827-2839. Epub 2022 Mar 30 doi: 10.1007/s00415-022-11050-w. PMID: 35353232Free PMC Article
Pérez-Bartolomé F, Sánchez-Quirós J
Arch Soc Esp Oftalmol (Engl Ed) 2021 Jan;96(1):32-40. Epub 2020 Aug 8 doi: 10.1016/j.oftal.2020.07.020. PMID: 32873480Free PMC Article
Tham SL, Prasad K, Umapathi T
Brain Behav 2018 May;8(5):e00960. Epub 2018 Apr 10 doi: 10.1002/brb3.960. PMID: 29761013Free PMC Article
Ansar V, Valadi N
Prim Care 2015 Jun;42(2):189-93. Epub 2015 Mar 20 doi: 10.1016/j.pop.2015.01.001. PMID: 25979580
Wakerley BR, Uncini A, Yuki N; GBS Classification Group; GBS Classification Group
Nat Rev Neurol 2014 Sep;10(9):537-44. Epub 2014 Jul 29 doi: 10.1038/nrneurol.2014.138. PMID: 25072194

Diagnosis

Gwathmey KG, Smith AG
Neurol Clin 2020 Aug;38(3):711-735. Epub 2020 Jun 11 doi: 10.1016/j.ncl.2020.03.008. PMID: 32703478
Al Othman B, Raabe J, Kini A, Lee AG
Curr Opin Ophthalmol 2019 Nov;30(6):462-466. doi: 10.1097/ICU.0000000000000611. PMID: 31567467
Wakerley BR, Uncini A, Yuki N; GBS Classification Group; GBS Classification Group
Nat Rev Neurol 2014 Sep;10(9):537-44. Epub 2014 Jul 29 doi: 10.1038/nrneurol.2014.138. PMID: 25072194
Shahrizaila N, Yuki N
J Neurol Neurosurg Psychiatry 2013 May;84(5):576-83. Epub 2012 Sep 15 doi: 10.1136/jnnp-2012-302824. PMID: 22984203
Teener JW
Semin Neurol 2012 Nov;32(5):512-6. Epub 2013 May 15 doi: 10.1055/s-0033-1334470. PMID: 23677659

Therapy

Kim JE, Yoon BA, Kim YH, Kim JK, Bae JS
Acta Neurol Scand 2022 Nov;146(5):604-609. Epub 2022 Aug 8 doi: 10.1111/ane.13687. PMID: 35938305Free PMC Article
Collantes MEV, Espiritu AI, Sy MCC, Anlacan VMM, Jamora RDG
Can J Neurol Sci 2021 Jan;48(1):66-76. Epub 2020 Jul 15 doi: 10.1017/cjn.2020.146. PMID: 32665054Free PMC Article
Al Othman B, Raabe J, Kini A, Lee AG
Curr Opin Ophthalmol 2019 Nov;30(6):462-466. doi: 10.1097/ICU.0000000000000611. PMID: 31567467
Wijdicks EF, Klein CJ
Mayo Clin Proc 2017 Mar;92(3):467-479. doi: 10.1016/j.mayocp.2016.12.002. PMID: 28259232
Ansar V, Valadi N
Prim Care 2015 Jun;42(2):189-93. Epub 2015 Mar 20 doi: 10.1016/j.pop.2015.01.001. PMID: 25979580

Prognosis

Harapan BN, Yoo HJ
J Neurol 2021 Sep;268(9):3059-3071. Epub 2021 Jan 23 doi: 10.1007/s00415-021-10406-y. PMID: 33486564Free PMC Article
Abu-Rumeileh S, Abdelhak A, Foschi M, Tumani H, Otto M
J Neurol 2021 Apr;268(4):1133-1170. Epub 2020 Aug 25 doi: 10.1007/s00415-020-10124-x. PMID: 32840686Free PMC Article
Gwathmey KG, Smith AG
Neurol Clin 2020 Aug;38(3):711-735. Epub 2020 Jun 11 doi: 10.1016/j.ncl.2020.03.008. PMID: 32703478
Tham SL, Prasad K, Umapathi T
Brain Behav 2018 May;8(5):e00960. Epub 2018 Apr 10 doi: 10.1002/brb3.960. PMID: 29761013Free PMC Article
Teener JW
Semin Neurol 2012 Nov;32(5):512-6. Epub 2013 May 15 doi: 10.1055/s-0033-1334470. PMID: 23677659

Clinical prediction guides

Vallat JM, Deschamps N, Taithe F, Richard L, Duchesne M, Magy L, Mathis S
J Neurol Sci 2022 Jul 15;438:120279. Epub 2022 May 10 doi: 10.1016/j.jns.2022.120279. PMID: 35576641
Bazán-Rodríguez L, López-Hernández JC, Jorge de Saráchaga A, Gómez-Figueroa E, Leon-Manriquez E, Briseño-Godinez ME, May-Mas R, Pérez-Valdez EY, Pérez-Jovel E, Vargas-Cañas S
Neurol Sci 2021 Oct;42(10):4225-4229. Epub 2021 Feb 16 doi: 10.1007/s10072-020-05029-6. PMID: 33594537
Harapan BN, Yoo HJ
J Neurol 2021 Sep;268(9):3059-3071. Epub 2021 Jan 23 doi: 10.1007/s00415-021-10406-y. PMID: 33486564Free PMC Article
Doets AY, Verboon C, van den Berg B, Harbo T, Cornblath DR, Willison HJ, Islam Z, Attarian S, Barroso FA, Bateman K, Benedetti L, van den Bergh P, Casasnovas C, Cavaletti G, Chavada G, Claeys KG, Dardiotis E, Davidson A, van Doorn PA, Feasby TE, Galassi G, Gorson KC, Hartung HP, Hsieh ST, Hughes RAC, Illa I, Islam B, Kusunoki S, Kuwabara S, Lehmann HC, Miller JAL, Mohammad QD, Monges S, Nobile Orazio E, Pardo J, Pereon Y, Rinaldi S, Querol L, Reddel SW, Reisin RC, Shahrizaila N, Sindrup SH, Waqar W, Jacobs BC; IGOS Consortium
Brain 2018 Oct 1;141(10):2866-2877. doi: 10.1093/brain/awy232. PMID: 30247567
van Doorn PA
Presse Med 2013 Jun;42(6 Pt 2):e193-201. Epub 2013 Apr 28 doi: 10.1016/j.lpm.2013.02.328. PMID: 23628447

Recent systematic reviews

Neophytou P, Artemiadis A, Hadjigeorgiou GM, Zis P
Acta Neurol Belg 2023 Oct;123(5):1693-1701. Epub 2023 Jul 19 doi: 10.1007/s13760-023-02336-5. PMID: 37468803Free PMC Article
Aladawi M, Elfil M, Abu-Esheh B, Abu Jazar D, Armouti A, Bayoumi A, Piccione E
Can J Neurol Sci 2022 Jan;49(1):38-48. Epub 2021 May 5 doi: 10.1017/cjn.2021.102. PMID: 33949300Free PMC Article
Chan JL, Murphy KA, Sarna JR
J Neurol 2021 Oct;268(10):3517-3548. Epub 2021 Feb 22 doi: 10.1007/s00415-021-10458-0. PMID: 33616739Free PMC Article
Abu-Rumeileh S, Abdelhak A, Foschi M, Tumani H, Otto M
J Neurol 2021 Apr;268(4):1133-1170. Epub 2020 Aug 25 doi: 10.1007/s00415-020-10124-x. PMID: 32840686Free PMC Article
Collantes MEV, Espiritu AI, Sy MCC, Anlacan VMM, Jamora RDG
Can J Neurol Sci 2021 Jan;48(1):66-76. Epub 2020 Jul 15 doi: 10.1017/cjn.2020.146. PMID: 32665054Free PMC Article

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