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Rickettsiaceae infectious disease

MedGen UID:
963887
•Concept ID:
CN281660
•
Disease or Syndrome
Synonyms: infection, Rickettsiaceae; infections, Rickettsiaceae; Rickettsiaceae caused disease or disorder; Rickettsiaceae disease or disorder; Rickettsiaceae infection; rickettsialpox
 
Monarch Initiative: MONDO:0006927

Definition

Infections with bacteria of the family rickettsiaceae. [from MONDO]

Professional guidelines

PubMed

Clinical Profile and Treatment Outcome in Scrub Typhus Patients in Central India.
Bansod YV, Aher AA, Bhole P, Rengaraj K, Jadhav P
J Assoc Physicians India 2021 Sep;69(9):11-12. PMID: 34585890
Follow-up investigation of antibody titers and diagnostic antibody cutoff values in patients with scrub typhus in South Korea.
Kim CM, Kim DM, Yun NR
BMC Infect Dis 2021 Jan 13;21(1):69. doi: 10.1186/s12879-020-05735-8. PMID: 33441087Free PMC Article
Ideal Criteria for Accurate Mouse Models of Vector-Borne Diseases with Emphasis on Scrub Typhus and Dengue.
Sarathy VV, Walker DH
Am J Trop Med Hyg 2020 Sep;103(3):970-975. doi: 10.4269/ajtmh.19-0955. PMID: 32602433Free PMC Article

Recent clinical studies

Etiology

Rickettsia-Host-Tick Interactions: Knowledge Advances and Gaps.
Kim HK
Infect Immun 2022 Sep 15;90(9):e0062121. Epub 2022 Aug 22 doi: 10.1128/iai.00621-21. PMID: 35993770Free PMC Article
Scrub Typhus and the Misconception of Doxycycline Resistance.
Wangrangsimakul T, Phuklia W, Newton PN, Richards AL, Day NPJ
Clin Infect Dis 2020 May 23;70(11):2444-2449. doi: 10.1093/cid/ciz972. PMID: 31570937Free PMC Article
Emerging and re-emerging rickettsial infections.
Adem PV
Semin Diagn Pathol 2019 May;36(3):146-151. Epub 2019 Apr 16 doi: 10.1053/j.semdp.2019.04.005. PMID: 31101391
Travel and tick-borne diseases: Lyme disease and beyond.
Parola P, Paddock CD
Travel Med Infect Dis 2018 Nov-Dec;26:1-2. Epub 2018 Sep 26 doi: 10.1016/j.tmaid.2018.09.010. PMID: 30267770
Rickettsiae as Emerging Infectious Agents.
Fang R, Blanton LS, Walker DH
Clin Lab Med 2017 Jun;37(2):383-400. doi: 10.1016/j.cll.2017.01.009. PMID: 28457356

Diagnosis

Revisiting the Overlooked Infection: Rickettsioses.
Lie KC, Nelwan EJ, Pasaribu A, Shakinah S, Sinto R, Nainggolan L
Acta Med Indones 2022 Oct;54(4):647-652. PMID: 36624720
Scrub typhus and antibiotic-resistant Orientia tsutsugamushi.
Lu CT, Wang LS, Hsueh PR
Expert Rev Anti Infect Ther 2021 Dec;19(12):1519-1527. Epub 2021 Jun 21 doi: 10.1080/14787210.2021.1941869. PMID: 34109905
Scrub typhus: a reemerging infection.
John R, Varghese GM
Curr Opin Infect Dis 2020 Oct;33(5):365-371. doi: 10.1097/QCO.0000000000000664. PMID: 32868511
Emerging and re-emerging rickettsial infections.
Adem PV
Semin Diagn Pathol 2019 May;36(3):146-151. Epub 2019 Apr 16 doi: 10.1053/j.semdp.2019.04.005. PMID: 31101391
Rickettsiae as Emerging Infectious Agents.
Fang R, Blanton LS, Walker DH
Clin Lab Med 2017 Jun;37(2):383-400. doi: 10.1016/j.cll.2017.01.009. PMID: 28457356

Therapy

Revisiting the Overlooked Infection: Rickettsioses.
Lie KC, Nelwan EJ, Pasaribu A, Shakinah S, Sinto R, Nainggolan L
Acta Med Indones 2022 Oct;54(4):647-652. PMID: 36624720
Scrub typhus and antibiotic-resistant Orientia tsutsugamushi.
Lu CT, Wang LS, Hsueh PR
Expert Rev Anti Infect Ther 2021 Dec;19(12):1519-1527. Epub 2021 Jun 21 doi: 10.1080/14787210.2021.1941869. PMID: 34109905
Scrub typhus: a reemerging infection.
John R, Varghese GM
Curr Opin Infect Dis 2020 Oct;33(5):365-371. doi: 10.1097/QCO.0000000000000664. PMID: 32868511
Rickettsiae as Emerging Infectious Agents.
Fang R, Blanton LS, Walker DH
Clin Lab Med 2017 Jun;37(2):383-400. doi: 10.1016/j.cll.2017.01.009. PMID: 28457356
Arthropod-borne bacterial diseases in pregnancy.
Dotters-Katz SK, Kuller J, Heine RP
Obstet Gynecol Surv 2013 Sep;68(9):635-49. doi: 10.1097/OGX.0b013e3182a5ed46. PMID: 25102120

Prognosis

Rickettsiales in the WHO European Region: an update from a One Health perspective.
Guccione C, Colomba C, Iaria C, Cascio A
Parasit Vectors 2023 Jan 30;16(1):41. doi: 10.1186/s13071-022-05646-4. PMID: 36717936Free PMC Article
Mapping the global distribution of spotted fever group rickettsiae: a systematic review with modelling analysis.
Zhang YY, Sun YQ, Chen JJ, Teng AY, Wang T, Li H, Hay SI, Fang LQ, Yang Y, Liu W
Lancet Digit Health 2023 Jan;5(1):e5-e15. Epub 2022 Nov 21 doi: 10.1016/S2589-7500(22)00212-6. PMID: 36424337Free PMC Article
Mediterranean spotted fever with multiorgan involvement.
Davis K, Ahmado A, Warrell CE, Downs LO, Furneaux J, Sithamparanathan K
BMJ Case Rep 2022 Dec 21;15(12) doi: 10.1136/bcr-2022-249426. PMID: 36543366Free PMC Article
Emerging Spotted Fever Rickettsioses in the United States.
Kidd L
Vet Clin North Am Small Anim Pract 2022 Nov;52(6):1305-1317. doi: 10.1016/j.cvsm.2022.07.003. PMID: 36336422
Secreted Wnt antagonists in scrub typhus.
Ueland T, Astrup E, Otterdal K, Lekva T, Janardhanan J, Prakash JAJ, Thomas K, Michelsen AE, Aukrust P, Varghese GM, Damås JK
PLoS Negl Trop Dis 2021 Apr;15(4):e0009185. Epub 2021 Apr 29 doi: 10.1371/journal.pntd.0009185. PMID: 33914733Free PMC Article

Clinical prediction guides

Geographical distribution of scrub typhus and risk of Orientia tsutsugamushi infection in Indonesia: Evidence mapping.
Saraswati K, Elliott I, Day NPJ, Baird JK, Blacksell SD, Ristiyanto, Moyes CL
PLoS Negl Trop Dis 2023 Sep;17(9):e0011412. Epub 2023 Sep 25 doi: 10.1371/journal.pntd.0011412. PMID: 37747922Free PMC Article
Rickettsiales in the WHO European Region: an update from a One Health perspective.
Guccione C, Colomba C, Iaria C, Cascio A
Parasit Vectors 2023 Jan 30;16(1):41. doi: 10.1186/s13071-022-05646-4. PMID: 36717936Free PMC Article
Mapping the global distribution of spotted fever group rickettsiae: a systematic review with modelling analysis.
Zhang YY, Sun YQ, Chen JJ, Teng AY, Wang T, Li H, Hay SI, Fang LQ, Yang Y, Liu W
Lancet Digit Health 2023 Jan;5(1):e5-e15. Epub 2022 Nov 21 doi: 10.1016/S2589-7500(22)00212-6. PMID: 36424337Free PMC Article
Antinuclear antibodies in infectious diseases.
Im JH, Chung MH, Park YK, Kwon HY, Baek JH, Lee SY, Lee JS
Infect Dis (Lond) 2020 Mar;52(3):177-185. Epub 2019 Nov 12 doi: 10.1080/23744235.2019.1690676. PMID: 31718355
Scrub Typhus and the Misconception of Doxycycline Resistance.
Wangrangsimakul T, Phuklia W, Newton PN, Richards AL, Day NPJ
Clin Infect Dis 2020 May 23;70(11):2444-2449. doi: 10.1093/cid/ciz972. PMID: 31570937Free PMC Article

Recent systematic reviews

Rickettsiales in the WHO European Region: an update from a One Health perspective.
Guccione C, Colomba C, Iaria C, Cascio A
Parasit Vectors 2023 Jan 30;16(1):41. doi: 10.1186/s13071-022-05646-4. PMID: 36717936Free PMC Article
Mapping the global distribution of spotted fever group rickettsiae: a systematic review with modelling analysis.
Zhang YY, Sun YQ, Chen JJ, Teng AY, Wang T, Li H, Hay SI, Fang LQ, Yang Y, Liu W
Lancet Digit Health 2023 Jan;5(1):e5-e15. Epub 2022 Nov 21 doi: 10.1016/S2589-7500(22)00212-6. PMID: 36424337Free PMC Article
Systematic review of the scrub typhus treatment landscape: Assessing the feasibility of an individual participant-level data (IPD) platform.
Saraswati K, Maguire BJ, McLean ARD, Singh-Phulgenda S, Ngu RC, Newton PN, Day NPJ, Guérin PJ
PLoS Negl Trop Dis 2021 Oct;15(10):e0009858. Epub 2021 Oct 14 doi: 10.1371/journal.pntd.0009858. PMID: 34648517Free PMC Article
A systematic review of the untreated mortality of murine typhus.
Doppler JF, Newton PN
PLoS Negl Trop Dis 2020 Sep;14(9):e0008641. Epub 2020 Sep 14 doi: 10.1371/journal.pntd.0008641. PMID: 32925913Free PMC Article
Under-diagnosis of rickettsial disease in clinical practice: A systematic review.
van Eekeren LE, de Vries SG, Wagenaar JFP, Spijker R, Grobusch MP, Goorhuis A
Travel Med Infect Dis 2018 Nov-Dec;26:7-15. Epub 2018 Mar 2 doi: 10.1016/j.tmaid.2018.02.006. PMID: 29486240

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