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Congenital spondylolysis of lumbosacral region

MedGen UID:
96576
Concept ID:
C0432162
Congenital Abnormality
Synonyms: Congenital lumbosacral spondylolysis; Congenital Spondylolysis, Lumbosacral Region
SNOMED CT: Congenital spondylolysis of lumbosacral region (80712009); Congenital lumbosacral spondylolysis (80712009)

Definition

A defect in the pars interarticularis of the vertebral arch of a lumbar or sacral vertebra that is present at the time of birth. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCongenital spondylolysis of lumbosacral region

Recent clinical studies

Etiology

Li X, Xu J, Rudd S, Li Z, Ding W, Yang S
J Vis Exp 2023 Feb 10;(192) doi: 10.3791/64802. PMID: 36847404
Sakai T, Goda Y, Tezuka F, Takata Y, Higashino K, Sato M, Mase Y, Nagamachi A, Sairyo K
Eur Spine J 2016 Feb;25(2):602-6. Epub 2015 May 26 doi: 10.1007/s00586-015-4029-4. PMID: 26006706
Sahin MS, Ergün A, Aslan A
Spine (Phila Pa 1976) 2015 Oct 1;40(19):E1058-62. doi: 10.1097/BRS.0000000000001070. PMID: 26230538
Patel AJ, Vadivelu S, Desai SK, Jea A
J Neurosurg Pediatr 2013 Jun;11(6):717-21. Epub 2013 Apr 19 doi: 10.3171/2013.3.PEDS12579. PMID: 23601017
Lahdenne P, Heikinheimo M, Jääskeläinen J, Merikanto J, Heikkilä J, Siimes MA
J Pediatr Orthop 1991 Sep-Oct;11(5):603-7. PMID: 1918346

Diagnosis

Kim YS, Kim H, Hong JH, Lee HJ, Kim MJ, Shin DH
Biomed Res Int 2018;2018:7406797. Epub 2018 Jun 27 doi: 10.1155/2018/7406797. PMID: 30050941Free PMC Article
Sakai T, Goda Y, Tezuka F, Takata Y, Higashino K, Sato M, Mase Y, Nagamachi A, Sairyo K
Eur Spine J 2016 Feb;25(2):602-6. Epub 2015 May 26 doi: 10.1007/s00586-015-4029-4. PMID: 26006706
Patel AJ, Vadivelu S, Desai SK, Jea A
J Neurosurg Pediatr 2013 Jun;11(6):717-21. Epub 2013 Apr 19 doi: 10.3171/2013.3.PEDS12579. PMID: 23601017
Popa I, Poenaru DV, Oprea MD, Andrei D
Eur J Orthop Surg Traumatol 2013 Jul;23 Suppl 1:S115-9. Epub 2013 Feb 8 doi: 10.1007/s00590-013-1185-2. PMID: 23412326

Prognosis

Anwar HA, Butler JS, Yarashi T, Rajakulendran K, Molloy S
Spine J 2015 Dec 1;15(12):2518-23. Epub 2015 Sep 25 doi: 10.1016/j.spinee.2015.09.021. PMID: 26407503
Lahdenne P, Heikinheimo M, Jääskeläinen J, Merikanto J, Heikkilä J, Siimes MA
J Pediatr Orthop 1991 Sep-Oct;11(5):603-7. PMID: 1918346

Clinical prediction guides

Anwar HA, Butler JS, Yarashi T, Rajakulendran K, Molloy S
Spine J 2015 Dec 1;15(12):2518-23. Epub 2015 Sep 25 doi: 10.1016/j.spinee.2015.09.021. PMID: 26407503
Lahdenne P, Heikinheimo M, Jääskeläinen J, Merikanto J, Heikkilä J, Siimes MA
J Pediatr Orthop 1991 Sep-Oct;11(5):603-7. PMID: 1918346

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