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Basal ganglia hemorrhage

MedGen UID:
96872
•Concept ID:
C0472377
•
Pathologic Function
Synonyms: Basal Ganglia Hemorrhage; Basal Ganglionic Hemorrhage; Ganglionic Hemorrhage, Basal; Hemorrhage, Basal Ganglia; Hemorrhage, Basal Ganglionic
SNOMED CT: Basal ganglia hemorrhage (195165005)

Definition

Bleeding within the subcortical regions of cerebral hemispheres (BASAL GANGLIA). It is often associated with HYPERTENSION or ARTERIOVENOUS MALFORMATIONS. Clinical manifestations may include HEADACHE; DYSKINESIAS; and HEMIPARESIS. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBasal ganglia hemorrhage

Professional guidelines

PubMed

Bilateral basal ganglia hemorrhage: a systematic review of etiologies, management strategies, and clinical outcomes.
Watanabe G, Conching A, Ogasawara C, Chavda V, Bin-Alamer O, Haider AS, Priola SM, Sharma M, Hoz SS, Chaurasia B, Umana GE, Palmisciano P
Neurosurg Rev 2023 Jun 5;46(1):135. doi: 10.1007/s10143-023-02044-x. PMID: 37273079Free PMC Article
Plasma ADAM-10 levels and functional outcome of acute primary basal ganglia hemorrhage.
Feng MJ, Wang W, Zhang XF, Che FF, Yang J, Ning WB, Gao W, Chen J
Clin Chim Acta 2022 Jan 1;524:18-24. Epub 2021 Nov 28 doi: 10.1016/j.cca.2021.11.026. PMID: 34852263
A Systematic Review and Meta-Analysis on the Treatment of Cerebral Hemorrhage with NaoXueShu Oral Liquid.
Wu L, Li Y, Wang X, Ren X, Zhu H, Sun Y, Xing Y, Zhu L, Gao Y, Shang H
Biomed Res Int 2017;2017:8542576. Epub 2017 May 29 doi: 10.1155/2017/8542576. PMID: 28630871Free PMC Article

Recent clinical studies

Etiology

Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage.
Pradilla G, Ratcliff JJ, Hall AJ, Saville BR, Allen JW, Paulon G, McGlothlin A, Lewis RJ, Fitzgerald M, Caveney AF, Li XT, Bain M, Gomes J, Jankowitz B, Zenonos G, Molyneaux BJ, Davies J, Siddiqui A, Chicoine MR, Keyrouz SG, Grossberg JA, Shah MV, Singh R, Bohnstedt BN, Frankel M, Wright DW, Barrow DL; ENRICH trial investigators; ENRICH Trial Investigators
N Engl J Med 2024 Apr 11;390(14):1277-1289. doi: 10.1056/NEJMoa2308440. PMID: 38598795
Fluoxetine for motor recovery after acute intracerebral hemorrhage, the FMRICH trial.
Marquez-Romero JM, Reyes-Martínez M, Huerta-Franco MR, Ruiz-Franco A, Silos H, Arauz A
Clin Neurol Neurosurg 2020 Mar;190:105656. Epub 2019 Dec 28 doi: 10.1016/j.clineuro.2019.105656. PMID: 31896491
Large traumatic basal ganglia hematoma: surgical treatment versus conservative management.
Baharvahdat H, Ganjifar B, Etemadrezaie H, Gorji A
J Neurosurg Sci 2020 Apr;64(2):154-157. Epub 2016 Nov 17 doi: 10.23736/S0390-5616.16.03830-3. PMID: 27854112
Massive Brain Swelling after Cranioplasty: A Case Report.
Zhang X, Pan B, Ye Z, Li Z, Mo F, Wang X
J Neurol Surg A Cent Eur Neurosurg 2019 Nov;80(6):498-502. Epub 2019 May 10 doi: 10.1055/s-0039-1688726. PMID: 31075809
Trans-venous embolization of a basal ganglia ruptured arteriovenous malformation with open surgical arterial control: A hybrid technique.
Kulcsár Z, Machi P, Schaller K, Lovblad KO, Bijlenga P
J Neuroradiol 2018 May;45(3):202-205. Epub 2018 Feb 2 doi: 10.1016/j.neurad.2017.12.021. PMID: 29410371

Diagnosis

Toluene Poisoning Presenting as Bilateral Basal Ganglia Haemorrhage.
Mahavar S, Chaturvedi A, Singh A, Kumar R, Dariya SS, Sharma R
J Assoc Physicians India 2018 Sep;66(9):93-94. PMID: 31321941
Antithrombotic medications and the etiology of intracerebral hemorrhage: MUCH-Italy.
Pezzini A, Grassi M, Paciaroni M, Zini A, Silvestrelli G, Del Zotto E, Caso V, Dell'Acqua ML, Giossi A, Volonghi I, Simone AM, Lanari A, Costa P, Poli L, Morotti A, De Giuli V, Pepe D, Gamba M, Ciccone A, Ritelli M, Colombi M, Agnelli G, Padovani A; Multicenter Study on Cerebral Hemorrhage in Italy (MUCH-Italy) Investigators
Neurology 2014 Feb 11;82(6):529-35. Epub 2014 Jan 15 doi: 10.1212/WNL.0000000000000108. PMID: 24431299
Cerebral vasculitis presenting as a stroke.
Montefort M, Dashora U, Chowdhury M
BMJ Case Rep 2012 Nov 27;2012 doi: 10.1136/bcr-2012-007194. PMID: 23188852Free PMC Article
Outcome of pediatric patients with traumatic basal ganglia hematoma: analysis of 21 cases.
Kurwale NS, Gupta DK, Mahapatra AK
Pediatr Neurosurg 2010;46(4):267-71. Epub 2010 Dec 16 doi: 10.1159/000321541. PMID: 21160235
Hyperacute intracerebral hemorrhage complicating carotid stenting should be distinguished from hyperperfusion syndrome.
Buhk JH, Cepek L, Knauth M
AJNR Am J Neuroradiol 2006 Aug;27(7):1508-13. PMID: 16908570Free PMC Article

Therapy

Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage.
Pradilla G, Ratcliff JJ, Hall AJ, Saville BR, Allen JW, Paulon G, McGlothlin A, Lewis RJ, Fitzgerald M, Caveney AF, Li XT, Bain M, Gomes J, Jankowitz B, Zenonos G, Molyneaux BJ, Davies J, Siddiqui A, Chicoine MR, Keyrouz SG, Grossberg JA, Shah MV, Singh R, Bohnstedt BN, Frankel M, Wright DW, Barrow DL; ENRICH trial investigators; ENRICH Trial Investigators
N Engl J Med 2024 Apr 11;390(14):1277-1289. doi: 10.1056/NEJMoa2308440. PMID: 38598795
Massive Brain Swelling after Cranioplasty: A Case Report.
Zhang X, Pan B, Ye Z, Li Z, Mo F, Wang X
J Neurol Surg A Cent Eur Neurosurg 2019 Nov;80(6):498-502. Epub 2019 May 10 doi: 10.1055/s-0039-1688726. PMID: 31075809
Toluene Poisoning Presenting as Bilateral Basal Ganglia Haemorrhage.
Mahavar S, Chaturvedi A, Singh A, Kumar R, Dariya SS, Sharma R
J Assoc Physicians India 2018 Sep;66(9):93-94. PMID: 31321941
Real-Time Distal, Multifocal, Repeated Lenticulostriate Bleeding Points during Thrombectomy in a Patient with Acute Variable M1 Occlusion: A Case Report and a Literature Review.
Peschillo S, Diana F, Colonnese C, Mellina V, Marzetti F, La Rosa I, Missori P
J Stroke Cerebrovasc Dis 2017 Oct;26(10):2082-2086. Epub 2017 Jun 1 doi: 10.1016/j.jstrokecerebrovasdis.2017.04.026. PMID: 28579509
Antithrombotic medications and the etiology of intracerebral hemorrhage: MUCH-Italy.
Pezzini A, Grassi M, Paciaroni M, Zini A, Silvestrelli G, Del Zotto E, Caso V, Dell'Acqua ML, Giossi A, Volonghi I, Simone AM, Lanari A, Costa P, Poli L, Morotti A, De Giuli V, Pepe D, Gamba M, Ciccone A, Ritelli M, Colombi M, Agnelli G, Padovani A; Multicenter Study on Cerebral Hemorrhage in Italy (MUCH-Italy) Investigators
Neurology 2014 Feb 11;82(6):529-35. Epub 2014 Jan 15 doi: 10.1212/WNL.0000000000000108. PMID: 24431299

Prognosis

Large traumatic basal ganglia hematoma: surgical treatment versus conservative management.
Baharvahdat H, Ganjifar B, Etemadrezaie H, Gorji A
J Neurosurg Sci 2020 Apr;64(2):154-157. Epub 2016 Nov 17 doi: 10.23736/S0390-5616.16.03830-3. PMID: 27854112
Simultaneous Bilateral Basal Ganglia Hemorrhage.
Yang Z, Chen J, Mu J
Curr Drug Deliv 2017 Sep 6;14(6):807-815. doi: 10.2174/1567201813666160607202811. PMID: 27305920
Antithrombotic medications and the etiology of intracerebral hemorrhage: MUCH-Italy.
Pezzini A, Grassi M, Paciaroni M, Zini A, Silvestrelli G, Del Zotto E, Caso V, Dell'Acqua ML, Giossi A, Volonghi I, Simone AM, Lanari A, Costa P, Poli L, Morotti A, De Giuli V, Pepe D, Gamba M, Ciccone A, Ritelli M, Colombi M, Agnelli G, Padovani A; Multicenter Study on Cerebral Hemorrhage in Italy (MUCH-Italy) Investigators
Neurology 2014 Feb 11;82(6):529-35. Epub 2014 Jan 15 doi: 10.1212/WNL.0000000000000108. PMID: 24431299
Association of interleukin-11 with mortality in patients with spontaneous basal ganglia haemorrhage.
Tu CJ, Liu WG, Dong XQ, Liu JS, Song DG, Yu WH, Zhang ZY, Zhen G, Lou HM
J Int Med Res 2011;39(4):1265-74. doi: 10.1177/147323001103900414. PMID: 21986128
Hyperacute intracerebral hemorrhage complicating carotid stenting should be distinguished from hyperperfusion syndrome.
Buhk JH, Cepek L, Knauth M
AJNR Am J Neuroradiol 2006 Aug;27(7):1508-13. PMID: 16908570Free PMC Article

Clinical prediction guides

Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage.
Pradilla G, Ratcliff JJ, Hall AJ, Saville BR, Allen JW, Paulon G, McGlothlin A, Lewis RJ, Fitzgerald M, Caveney AF, Li XT, Bain M, Gomes J, Jankowitz B, Zenonos G, Molyneaux BJ, Davies J, Siddiqui A, Chicoine MR, Keyrouz SG, Grossberg JA, Shah MV, Singh R, Bohnstedt BN, Frankel M, Wright DW, Barrow DL; ENRICH trial investigators; ENRICH Trial Investigators
N Engl J Med 2024 Apr 11;390(14):1277-1289. doi: 10.1056/NEJMoa2308440. PMID: 38598795
Fluoxetine for motor recovery after acute intracerebral hemorrhage, the FMRICH trial.
Marquez-Romero JM, Reyes-Martínez M, Huerta-Franco MR, Ruiz-Franco A, Silos H, Arauz A
Clin Neurol Neurosurg 2020 Mar;190:105656. Epub 2019 Dec 28 doi: 10.1016/j.clineuro.2019.105656. PMID: 31896491
Large traumatic basal ganglia hematoma: surgical treatment versus conservative management.
Baharvahdat H, Ganjifar B, Etemadrezaie H, Gorji A
J Neurosurg Sci 2020 Apr;64(2):154-157. Epub 2016 Nov 17 doi: 10.23736/S0390-5616.16.03830-3. PMID: 27854112
Antithrombotic medications and the etiology of intracerebral hemorrhage: MUCH-Italy.
Pezzini A, Grassi M, Paciaroni M, Zini A, Silvestrelli G, Del Zotto E, Caso V, Dell'Acqua ML, Giossi A, Volonghi I, Simone AM, Lanari A, Costa P, Poli L, Morotti A, De Giuli V, Pepe D, Gamba M, Ciccone A, Ritelli M, Colombi M, Agnelli G, Padovani A; Multicenter Study on Cerebral Hemorrhage in Italy (MUCH-Italy) Investigators
Neurology 2014 Feb 11;82(6):529-35. Epub 2014 Jan 15 doi: 10.1212/WNL.0000000000000108. PMID: 24431299
Outcome of pediatric patients with traumatic basal ganglia hematoma: analysis of 21 cases.
Kurwale NS, Gupta DK, Mahapatra AK
Pediatr Neurosurg 2010;46(4):267-71. Epub 2010 Dec 16 doi: 10.1159/000321541. PMID: 21160235

Recent systematic reviews

Bilateral basal ganglia hemorrhage: a systematic review of etiologies, management strategies, and clinical outcomes.
Watanabe G, Conching A, Ogasawara C, Chavda V, Bin-Alamer O, Haider AS, Priola SM, Sharma M, Hoz SS, Chaurasia B, Umana GE, Palmisciano P
Neurosurg Rev 2023 Jun 5;46(1):135. doi: 10.1007/s10143-023-02044-x. PMID: 37273079Free PMC Article
Spontaneous Simultaneous Bilateral Basal Ganglia Hemorrhage (SSBBGH): Systematic Review and Data Analysis on Epidemiology, Clinical Feature, Location of Bleeding, Etiology, Therapeutic Intervention and Outcome.
Alhashim A, Hadhiah K, Al-Dandan H, Aljaman M, Alabdali M, Alshurem M, Aljaafari D, AlQarni M
Vasc Health Risk Manag 2022;18:267-276. Epub 2022 Apr 14 doi: 10.2147/VHRM.S349912. PMID: 35444424Free PMC Article
Hematoma location and morphology of anticoagulation-associated intracerebral hemorrhage.
Seiffge DJ, Curtze S, Dequatre-Ponchelle N, Pezzini A, Tatlisumak T, Cordonnier C, Werring D
Neurology 2019 Feb 19;92(8):e782-e791. Epub 2019 Jan 23 doi: 10.1212/WNL.0000000000006958. PMID: 30674603

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