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Major salivary gland cancer

MedGen UID:
96919
Concept ID:
C0496763
Neoplastic Process
Synonyms: cancer of major salivary gland; major salivary gland cancer; Malignant Major Salivary Gland Neoplasm; malignant major salivary gland neoplasm; Malignant Major Salivary Gland Tumor; malignant major salivary gland tumor; malignant major salivary gland tumour; Malignant Neoplasm of Major Salivary Gland; malignant neoplasm of major salivary gland; Malignant neoplasm of major salivary glands; malignant neoplasm of major salivary glands; Malignant Neoplasm of the Major Salivary Gland; malignant neoplasm of the major salivary gland; Malignant tumor of major salivary gland; Malignant Tumor of Major Salivary Gland; malignant tumor of major salivary gland; Malignant Tumor of the Major Salivary Gland; malignant tumor of the major salivary gland; malignant tumour of major salivary gland; malignant tumour of the major salivary gland
SNOMED CT: Malignant neoplasm of major salivary glands (363378008); Malignant tumor of major salivary gland (363378008)
 
Monarch Initiative: MONDO:0044743

Definition

A primary or metastatic malignant neoplasm affecting the major salivary glands. Representative examples include carcinoma, lymphoma, and sarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMajor salivary gland cancer

Professional guidelines

PubMed

Barry B, Verillaud B, Jegoux F, Pham Dang N, Baujat B, Chabrillac E, Vergez S, Fakhry N
Eur Ann Otorhinolaryngol Head Neck Dis 2024 May;141(3):153-160. Epub 2023 Nov 30 doi: 10.1016/j.anorl.2023.11.005. PMID: 38040591
Jegadeesh N, Liu Y, Prabhu RS, Magliocca KR, Marcus DM, Higgins KA, Vainshtein JM, Trad Wadsworth J, Beitler JJ
Oral Oncol 2015 Aug;51(8):770-7. Epub 2015 May 29 doi: 10.1016/j.oraloncology.2015.05.005. PMID: 26033470Free PMC Article
Armstrong JG, Harrison LB, Spiro RH, Fass DE, Strong EW, Fuks ZY
J Surg Oncol 1990 Jul;44(3):138-41. doi: 10.1002/jso.2930440303. PMID: 2370797

Recent clinical studies

Etiology

Patel AM, Haleem A, Choudhry HS, Povolotskiy R, Roden DF
Otolaryngol Head Neck Surg 2024 Jul;171(1):155-171. Epub 2024 Mar 14 doi: 10.1002/ohn.715. PMID: 38482915
Benchetrit L, Mehra S, Mahajan A, Rahmati RW, Judson BL, Edwards HA
Otolaryngol Head Neck Surg 2022 Aug;167(2):305-315. Epub 2021 Nov 16 doi: 10.1177/01945998211058354. PMID: 34784258
Saraswathula A, Megwalu UC
Otolaryngol Head Neck Surg 2018 Dec;159(6):998-1005. Epub 2018 Oct 16 doi: 10.1177/0194599818791798. PMID: 30324868
Stennert E, Wittekindt C, Klussmann JP, Guntinas-Lichius O
Otolaryngol Pol 2004;58(1):109-14. PMID: 15101269
Armstrong JG, Harrison LB, Spiro RH, Fass DE, Strong EW, Fuks ZY
J Surg Oncol 1990 Jul;44(3):138-41. doi: 10.1002/jso.2930440303. PMID: 2370797

Diagnosis

Barry B, Verillaud B, Jegoux F, Pham Dang N, Baujat B, Chabrillac E, Vergez S, Fakhry N
Eur Ann Otorhinolaryngol Head Neck Dis 2024 May;141(3):153-160. Epub 2023 Nov 30 doi: 10.1016/j.anorl.2023.11.005. PMID: 38040591
Costantino A, Canali L, Festa BM, Kim SH, Spriano G, De Virgilio A
Eur J Surg Oncol 2023 Sep;49(9):106965. Epub 2023 Jun 27 doi: 10.1016/j.ejso.2023.06.017. PMID: 37393130
Benchetrit L, Mehra S, Mahajan A, Rahmati RW, Judson BL, Edwards HA
Otolaryngol Head Neck Surg 2022 Aug;167(2):305-315. Epub 2021 Nov 16 doi: 10.1177/01945998211058354. PMID: 34784258
Saraswathula A, Megwalu UC
Otolaryngol Head Neck Surg 2018 Dec;159(6):998-1005. Epub 2018 Oct 16 doi: 10.1177/0194599818791798. PMID: 30324868
Witt RL
Surg Oncol Clin N Am 2004 Jan;13(1):113-27. doi: 10.1016/S1055-3207(03)00126-1. PMID: 15062365

Therapy

Patel AM, Haleem A, Choudhry HS, Brant JA, Brody RM, Carey RM
Otolaryngol Head Neck Surg 2024 May;170(5):1349-1363. Epub 2024 Mar 1 doi: 10.1002/ohn.686. PMID: 38426575
Costantino A, Canali L, Festa BM, Kim SH, Spriano G, De Virgilio A
Eur J Surg Oncol 2023 Sep;49(9):106965. Epub 2023 Jun 27 doi: 10.1016/j.ejso.2023.06.017. PMID: 37393130
Chuong M, Bryant J, Hartsell W, Larson G, Badiyan S, Laramore GE, Katz S, Tsai H, Vargas C
Acta Oncol 2020 Feb;59(2):196-200. Epub 2019 Dec 5 doi: 10.1080/0284186X.2019.1698764. PMID: 31805791
Kordzińska-Cisek I, Grzybowska-Szatkowska L
Otolaryngol Pol 2019 Apr 5;73(3):26-31. doi: 10.5604/01.3001.0013.0508. PMID: 31249150
Romesser PB, Cahlon O, Scher E, Zhou Y, Berry SL, Rybkin A, Sine KM, Tang S, Sherman EJ, Wong R, Lee NY
Radiother Oncol 2016 Feb;118(2):286-92. Epub 2016 Feb 8 doi: 10.1016/j.radonc.2015.12.008. PMID: 26867969Free PMC Article

Prognosis

Patel AM, Haleem A, Choudhry HS, Povolotskiy R, Roden DF
Otolaryngol Head Neck Surg 2024 Jul;171(1):155-171. Epub 2024 Mar 14 doi: 10.1002/ohn.715. PMID: 38482915
Benchetrit L, Mehra S, Mahajan A, Rahmati RW, Judson BL, Edwards HA
Otolaryngol Head Neck Surg 2022 Aug;167(2):305-315. Epub 2021 Nov 16 doi: 10.1177/01945998211058354. PMID: 34784258
Saraswathula A, Megwalu UC
Otolaryngol Head Neck Surg 2018 Dec;159(6):998-1005. Epub 2018 Oct 16 doi: 10.1177/0194599818791798. PMID: 30324868
Li Y, Ju J, Liu X, Gao T, Wang Z, Ni Q, Ma C, Zhao Z, Ren Y, Sun M
Oncotarget 2017 Apr 11;8(15):24469-24482. doi: 10.18632/oncotarget.14905. PMID: 28160551Free PMC Article
Armstrong JG, Harrison LB, Spiro RH, Fass DE, Strong EW, Fuks ZY
J Surg Oncol 1990 Jul;44(3):138-41. doi: 10.1002/jso.2930440303. PMID: 2370797

Clinical prediction guides

Costantino A, Canali L, Festa BM, Kim SH, Spriano G, De Virgilio A
Eur J Surg Oncol 2023 Sep;49(9):106965. Epub 2023 Jun 27 doi: 10.1016/j.ejso.2023.06.017. PMID: 37393130
Benchetrit L, Mehra S, Mahajan A, Rahmati RW, Judson BL, Edwards HA
Otolaryngol Head Neck Surg 2022 Aug;167(2):305-315. Epub 2021 Nov 16 doi: 10.1177/01945998211058354. PMID: 34784258
Mimica X, Yuan A, Hay A, Katabi N, Zanoni DK, Valero C, Shah JP, Wong RJ, Cohen MA, Patel SG, Ganly I
Oral Oncol 2021 Dec;123:105602. Epub 2021 Nov 9 doi: 10.1016/j.oraloncology.2021.105602. PMID: 34768210Free PMC Article
Li Y, Ju J, Liu X, Gao T, Wang Z, Ni Q, Ma C, Zhao Z, Ren Y, Sun M
Oncotarget 2017 Apr 11;8(15):24469-24482. doi: 10.18632/oncotarget.14905. PMID: 28160551Free PMC Article
Armstrong JG, Harrison LB, Spiro RH, Fass DE, Strong EW, Fuks ZY
J Surg Oncol 1990 Jul;44(3):138-41. doi: 10.1002/jso.2930440303. PMID: 2370797

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