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Atrophic lichen planus

MedGen UID:
9754
•Concept ID:
C0023647
•
Disease or Syndrome
Synonyms: Atrophic Lichen Planus; atrophic lichen planus; Atrophic LP; atrophic LP; Lichen planus atrophicus
SNOMED CT: Lichen planus atrophicus (25858008); Atrophic lichen planus (25858008)
 
Monarch Initiative: MONDO:0016773
Orphanet: ORPHA254449

Definition

A rare variant of cutaneous lichen planus characterized by the development of pale papules or plaques with an atrophic center. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAtrophic lichen planus
Follow this link to review classifications for Atrophic lichen planus in Orphanet.

Professional guidelines

PubMed

Efficacy of Topical Treatments for the Management of Symptomatic Oral Lichen Planus: A Systematic Review.
Serafini G, De Biase A, Lamazza L, Mazzucchi G, Lollobrigida M
Int J Environ Res Public Health 2023 Jan 10;20(2) doi: 10.3390/ijerph20021202. PMID: 36673955Free PMC Article

Recent clinical studies

Etiology

Clinical value and potential circulating of miR-99a as tumor suppressor biomarker in serum of oral squamous cell carcinoma and erosive atrophic lichen planus.
Farshbaf A, Mohtasham N, Shamshiri AK, Khazaeni K, Aghaee-Bakhtiari SH, Arab F, Cheshomi M, Hassanabadi M, Mohajertehran F
J Stomatol Oral Maxillofac Surg 2024 Jun;125(3S):101806. Epub 2024 Feb 24 doi: 10.1016/j.jormas.2024.101806. PMID: 38408642
Evaluation of Potential Risk Factors that contribute to Malignant Transformation of Oral Lichen Planus: A Literature Review.
Agha-Hosseini F, Sheykhbahaei N, SadrZadeh-Afshar MS
J Contemp Dent Pract 2016 Aug 1;17(8):692-701. doi: 10.5005/jp-journals-10024-1914. PMID: 27659090
Human papillomavirus in oral atrophic lichen planus lesions.
Mattila R, Rautava J, Syrjänen S
Oral Oncol 2012 Oct;48(10):980-984. Epub 2012 Jun 2 doi: 10.1016/j.oraloncology.2012.04.009. PMID: 22658678
Desmocollin expression in oral atrophic lichen planus correlates with clinical behavior and DNA content.
Mattila R, Alanen K, Syrjänen S
J Cutan Pathol 2008 Sep;35(9):832-8. Epub 2008 Apr 18 doi: 10.1111/j.1600-0560.2007.00903.x. PMID: 18422976
Annular atrophic lichen planus and Sneddon's syndrome.
Lipsker D, Piette JC, Laporte JL, Maunoury L, Francès C
Dermatology 1997;195(4):402-3. doi: 10.1159/000245999. PMID: 9529568

Diagnosis

Annular atrophic lichen planus: a review of the literature.
Santhosh P, George M
Int J Dermatol 2022 Oct;61(10):1213-1217. Epub 2022 Jan 22 doi: 10.1111/ijd.16038. PMID: 35064678
A case of annular atrophic lichen planus in a child and review of the literature.
Sears S, Daftary K, Burch A, Todd P
Pediatr Dermatol 2021 Sep;38(5):1283-1287. Epub 2021 Sep 24 doi: 10.1111/pde.14812. PMID: 34561910
Annular atrophic lichen planus.
Mai S, Mansouri S, Hassam B
BMJ Case Rep 2019 Jul 15;12(7) doi: 10.1136/bcr-2019-229270. PMID: 31308186Free PMC Article
Human papillomavirus in oral atrophic lichen planus lesions.
Mattila R, Rautava J, Syrjänen S
Oral Oncol 2012 Oct;48(10):980-984. Epub 2012 Jun 2 doi: 10.1016/j.oraloncology.2012.04.009. PMID: 22658678
Atrophic lichen planus.
Tonsager M, Crutchfield CE 3rd
Dermatol Nurs 2004 Feb;16(1):73-4. PMID: 15022509

Therapy

Efficacy of Topical Treatments for the Management of Symptomatic Oral Lichen Planus: A Systematic Review.
Serafini G, De Biase A, Lamazza L, Mazzucchi G, Lollobrigida M
Int J Environ Res Public Health 2023 Jan 10;20(2) doi: 10.3390/ijerph20021202. PMID: 36673955Free PMC Article
Annular atrophic lichen planus: a review of the literature.
Santhosh P, George M
Int J Dermatol 2022 Oct;61(10):1213-1217. Epub 2022 Jan 22 doi: 10.1111/ijd.16038. PMID: 35064678
Annular atrophic lichen planus induced by anti-HER2 antibodies.
Chawla S, Turner N, Terlizzo M, Heelan K
Australas J Dermatol 2021 May;62(2):210-212. Epub 2020 Nov 20 doi: 10.1111/ajd.13501. PMID: 33216943
Annular atrophic lichen planus.
Mai S, Mansouri S, Hassam B
BMJ Case Rep 2019 Jul 15;12(7) doi: 10.1136/bcr-2019-229270. PMID: 31308186Free PMC Article
Annular atrophic lichen planus responds to hydroxychloroquine and acitretin.
Eyler JT, Garib G, Thompson KR, Dahiya M, Swan JW
Cutis 2017 Aug;100(2):119-122. PMID: 28961283

Prognosis

Clinical value and potential circulating of miR-99a as tumor suppressor biomarker in serum of oral squamous cell carcinoma and erosive atrophic lichen planus.
Farshbaf A, Mohtasham N, Shamshiri AK, Khazaeni K, Aghaee-Bakhtiari SH, Arab F, Cheshomi M, Hassanabadi M, Mohajertehran F
J Stomatol Oral Maxillofac Surg 2024 Jun;125(3S):101806. Epub 2024 Feb 24 doi: 10.1016/j.jormas.2024.101806. PMID: 38408642
Annular atrophic lichen planus: a review of the literature.
Santhosh P, George M
Int J Dermatol 2022 Oct;61(10):1213-1217. Epub 2022 Jan 22 doi: 10.1111/ijd.16038. PMID: 35064678
Human papillomavirus in oral atrophic lichen planus lesions.
Mattila R, Rautava J, Syrjänen S
Oral Oncol 2012 Oct;48(10):980-984. Epub 2012 Jun 2 doi: 10.1016/j.oraloncology.2012.04.009. PMID: 22658678
Desmocollin expression in oral atrophic lichen planus correlates with clinical behavior and DNA content.
Mattila R, Alanen K, Syrjänen S
J Cutan Pathol 2008 Sep;35(9):832-8. Epub 2008 Apr 18 doi: 10.1111/j.1600-0560.2007.00903.x. PMID: 18422976
Annular atrophic lichen planus and Sneddon's syndrome.
Lipsker D, Piette JC, Laporte JL, Maunoury L, Francès C
Dermatology 1997;195(4):402-3. doi: 10.1159/000245999. PMID: 9529568

Clinical prediction guides

Mucocutaneous Changes in End-Stage Renal Disease Under Regular Hemodialysis - A Cross-Sectional Study.
Ras AA, Kheir El Din NH, Talaat AM, Hussein RR, Khalil E
Indian J Dent Res 2023 Apr-Jun;34(2):130-135. doi: 10.4103/ijdr.IJDR_802_20. PMID: 37787198
A comparative pilot study of low intensity laser versus topical corticosteroids in the treatment of erosive-atrophic oral lichen planus.
Jajarm HH, Falaki F, Mahdavi O
Photomed Laser Surg 2011 Jun;29(6):421-5. Epub 2011 Jan 8 doi: 10.1089/pho.2010.2876. PMID: 21214369
Desmocollin expression in oral atrophic lichen planus correlates with clinical behavior and DNA content.
Mattila R, Alanen K, Syrjänen S
J Cutan Pathol 2008 Sep;35(9):832-8. Epub 2008 Apr 18 doi: 10.1111/j.1600-0560.2007.00903.x. PMID: 18422976
Annular atrophic lichen planus.
Ponce-Olivera RM, Tirado-Sánchez A, Montes-de-Oca-Sánchez G, León-Dorantes G, Mercadillo-Pérez P
Int J Dermatol 2007 May;46(5):490-1. doi: 10.1111/j.1365-4632.2007.02964.x. PMID: 17472678
A clinical study of 674 patients with oral lichen planus in China.
Xue JL, Fan MW, Wang SZ, Chen XM, Li Y, Wang L
J Oral Pathol Med 2005 Sep;34(8):467-72. doi: 10.1111/j.1600-0714.2005.00341.x. PMID: 16091113

Recent systematic reviews

Efficacy of Topical Treatments for the Management of Symptomatic Oral Lichen Planus: A Systematic Review.
Serafini G, De Biase A, Lamazza L, Mazzucchi G, Lollobrigida M
Int J Environ Res Public Health 2023 Jan 10;20(2) doi: 10.3390/ijerph20021202. PMID: 36673955Free PMC Article

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