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Neoplasm of the lip

MedGen UID:
9777
•Concept ID:
C0023761
•
Neoplastic Process
Synonym: Lip neoplasm
SNOMED CT: Tumor of lip (126770008); Neoplasm of lip (126770008)
 
HPO: HP:0100604
Monarch Initiative: MONDO:0021249

Definition

A tumor (abnormal growth of tissue) of the lip. [from HPO]

Professional guidelines

PubMed

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).
Lyon AR, López-Fernández T, Couch LS, Asteggiano R, Aznar MC, Bergler-Klein J, Boriani G, Cardinale D, Cordoba R, Cosyns B, Cutter DJ, de Azambuja E, de Boer RA, Dent SF, Farmakis D, Gevaert SA, Gorog DA, Herrmann J, Lenihan D, Moslehi J, Moura B, Salinger SS, Stephens R, Suter TM, Szmit S, Tamargo J, Thavendiranathan P, Tocchetti CG, van der Meer P, van der Pal HJH; ESC Scientific Document Group
Eur Heart J 2022 Nov 1;43(41):4229-4361. doi: 10.1093/eurheartj/ehac244. PMID: 36017568
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC.
Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, Falk V, González-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GMC, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P; ESC Scientific Document Group
Eur Heart J 2016 Jul 14;37(27):2129-2200. Epub 2016 May 20 doi: 10.1093/eurheartj/ehw128. PMID: 27206819
2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM).
Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, Dulgheru R, El Khoury G, Erba PA, Iung B, Miro JM, Mulder BJ, Plonska-Gosciniak E, Price S, Roos-Hesselink J, Snygg-Martin U, Thuny F, Tornos Mas P, Vilacosta I, Zamorano JL; ESC Scientific Document Group
Eur Heart J 2015 Nov 21;36(44):3075-3128. Epub 2015 Aug 29 doi: 10.1093/eurheartj/ehv319. PMID: 26320109

Recent clinical studies

Etiology

Occupational variation in the incidence of lip cancer in the Nordic countries.
Mroueh R, Carpén T, Mäkitie A, Hansen J, Heikkinen S, Lynge E, Martinsen JI, Selander J, Mehlum IS, Torfadottir JE, Salo T, Pukkala E
Acta Oncol 2023 Jun;62(6):541-549. Epub 2023 Jun 19 doi: 10.1080/0284186X.2023.2224053. PMID: 37337140
Does hydrochlorothiazide increase the incidence of skin, lip and oral cancer in a UK population?
Carney K, Cousins M
Evid Based Dent 2022 Mar;23(1):38-39. Epub 2022 Mar 25 doi: 10.1038/s41432-022-0255-x. PMID: 35338330
Global patterns and trends in cancers of the lip, tongue and mouth.
Miranda-Filho A, Bray F
Oral Oncol 2020 Mar;102:104551. Epub 2020 Jan 25 doi: 10.1016/j.oraloncology.2019.104551. PMID: 31986342
Ultraviolet radiation.
Gallagher RP, Lee TK, Bajdik CD, Borugian M
Chronic Dis Can 2010;29 Suppl 1:51-68. PMID: 21199599
Lip reconstruction.
Ishii LE, Byrne PJ
Facial Plast Surg Clin North Am 2009 Aug;17(3):445-53. doi: 10.1016/j.fsc.2009.05.007. PMID: 19698922

Diagnosis

Does hydrochlorothiazide increase the incidence of skin, lip and oral cancer in a UK population?
Carney K, Cousins M
Evid Based Dent 2022 Mar;23(1):38-39. Epub 2022 Mar 25 doi: 10.1038/s41432-022-0255-x. PMID: 35338330
ANGIOMYOMA OF THE UPPER LIP - CASE REPORT AND REVIEW OF THE LITERATURE.
Perić B, Vidaković B, Grgić N, Manojlović S, Čavka H
Acta Clin Croat 2019 Mar;58(1):183-186. doi: 10.20471/acc.2019.58.01.24. PMID: 31363342Free PMC Article
Differential diagnoses of elevated lesions of the upper lip: An overview.
Bhandarkar GP, Shetty KV
J Cancer Res Ther 2017 Apr-Jun;13(2):170-174. doi: 10.4103/0973-1482.204890. PMID: 28643729
Oral cavity and lip cancer: United Kingdom National Multidisciplinary Guidelines.
Kerawala C, Roques T, Jeannon JP, Bisase B
J Laryngol Otol 2016 May;130(S2):S83-S89. doi: 10.1017/S0022215116000499. PMID: 27841120Free PMC Article
Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects.
Vieira RA, Minicucci EM, Marques ME, Marques SA
An Bras Dermatol 2012 Jan-Feb;87(1):105-14. doi: 10.1590/s0365-05962012000100013. PMID: 22481658

Therapy

Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Cui Z, Wang H, Li S, Qin T, Shi H, Ma J, Li L, Yu G, Jiang T, Li C
J Pharmacol Sci 2022 Jan;148(1):73-85. Epub 2021 Oct 2 doi: 10.1016/j.jphs.2021.09.008. PMID: 34924133
Pointless spatial modeling.
Wilson K, Wakefield J
Biostatistics 2020 Apr 1;21(2):e17-e32. doi: 10.1093/biostatistics/kxy041. PMID: 30202860Free PMC Article
Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice.
Yue W, Chen L, Yu L, Zhou B, Yin H, Ren W, Liu C, Guo L, Zhang Y, Sun L, Zhang K, Xu H, Chen Y
Nat Commun 2019 May 2;10(1):2025. doi: 10.1038/s41467-019-09760-3. PMID: 31048681Free PMC Article
Risk Factors for Cutaneous Squamous Cell Carcinoma Recurrence, Metastasis, and Disease-Specific Death: A Systematic Review and Meta-analysis.
Thompson AK, Kelley BF, Prokop LJ, Murad MH, Baum CL
JAMA Dermatol 2016 Apr;152(4):419-28. doi: 10.1001/jamadermatol.2015.4994. PMID: 26762219Free PMC Article
Ultraviolet radiation.
Gallagher RP, Lee TK, Bajdik CD, Borugian M
Chronic Dis Can 2010;29 Suppl 1:51-68. PMID: 21199599

Prognosis

Occupational variation in the incidence of lip cancer in the Nordic countries.
Mroueh R, Carpén T, Mäkitie A, Hansen J, Heikkinen S, Lynge E, Martinsen JI, Selander J, Mehlum IS, Torfadottir JE, Salo T, Pukkala E
Acta Oncol 2023 Jun;62(6):541-549. Epub 2023 Jun 19 doi: 10.1080/0284186X.2023.2224053. PMID: 37337140
Does hydrochlorothiazide increase the incidence of skin, lip and oral cancer in a UK population?
Carney K, Cousins M
Evid Based Dent 2022 Mar;23(1):38-39. Epub 2022 Mar 25 doi: 10.1038/s41432-022-0255-x. PMID: 35338330
Global patterns and trends in cancers of the lip, tongue and mouth.
Miranda-Filho A, Bray F
Oral Oncol 2020 Mar;102:104551. Epub 2020 Jan 25 doi: 10.1016/j.oraloncology.2019.104551. PMID: 31986342
Prevalence and incidence of oral cancer in low- and middle-income countries: A scoping review.
Shrestha AD, Vedsted P, Kallestrup P, Neupane D
Eur J Cancer Care (Engl) 2020 Mar;29(2):e13207. Epub 2019 Dec 10 doi: 10.1111/ecc.13207. PMID: 31820851
Global epidemiology of oral and oropharyngeal cancer.
Warnakulasuriya S
Oral Oncol 2009 Apr-May;45(4-5):309-16. Epub 2008 Sep 18 doi: 10.1016/j.oraloncology.2008.06.002. PMID: 18804401

Clinical prediction guides

The winning score.
Brown AC, Mortimer NJ, Salmon PJM
Australas J Dermatol 2022 Nov;63(4):e329-e330. Epub 2022 Oct 5 doi: 10.1111/ajd.13931. PMID: 36197678
Sodium molybdate inhibits the growth of ovarian cancer cells via inducing both ferroptosis and apoptosis.
Mao G, Xin D, Wang Q, Lai D
Free Radic Biol Med 2022 Mar;182:79-92. Epub 2022 Feb 24 doi: 10.1016/j.freeradbiomed.2022.02.023. PMID: 35219846
Global patterns and trends in cancers of the lip, tongue and mouth.
Miranda-Filho A, Bray F
Oral Oncol 2020 Mar;102:104551. Epub 2020 Jan 25 doi: 10.1016/j.oraloncology.2019.104551. PMID: 31986342
Pointless spatial modeling.
Wilson K, Wakefield J
Biostatistics 2020 Apr 1;21(2):e17-e32. doi: 10.1093/biostatistics/kxy041. PMID: 30202860Free PMC Article
Colposcopy.
Pretorius RG, Belinson JL
Minerva Ginecol 2012 Apr;64(2):173-80. PMID: 22481626

Recent systematic reviews

Laser Therapy for the Treatment of Actinic Cheilitis: A Systematic Review.
Ayen-Rodriguez A, Naranjo-Diaz MJ, Ruiz-Villaverde R
Int J Environ Res Public Health 2022 Apr 11;19(8) doi: 10.3390/ijerph19084593. PMID: 35457467Free PMC Article
Relationship between non-syndromic oral clefts and cancer: A systematic review and meta-analysis.
Machado RA, Popoff DAV, Martelli-Júnior H
Oral Dis 2022 Jul;28(5):1369-1386. Epub 2022 Mar 22 doi: 10.1111/odi.14179. PMID: 35258156
Cribriform adenocarcinoma of the tongue and minor salivary glands: a systematic review of an uncommon clinicopathological entity.
De Luca P, Tassone D, de Campora L, Simone M, Marra P, Colacurcio V, Scarpa A, Costarelli L, Camaioni A
Eur Arch Otorhinolaryngol 2022 Jun;279(6):2719-2725. Epub 2021 Oct 23 doi: 10.1007/s00405-021-07140-6. PMID: 34687340
Canalicular adenoma: A systematic review.
Peraza AJ, Wright J, Gómez R
J Craniomaxillofac Surg 2017 Oct;45(10):1754-1758. Epub 2017 Aug 3 doi: 10.1016/j.jcms.2017.07.020. PMID: 28890252
Risk Factors for Cutaneous Squamous Cell Carcinoma Recurrence, Metastasis, and Disease-Specific Death: A Systematic Review and Meta-analysis.
Thompson AK, Kelley BF, Prokop LJ, Murad MH, Baum CL
JAMA Dermatol 2016 Apr;152(4):419-28. doi: 10.1001/jamadermatol.2015.4994. PMID: 26762219Free PMC Article

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