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Leukoplakia of larynx

MedGen UID:: 97879
•Concept ID:: C0392050
•: Disease or Syndrome

Synonyms:	Keratosis of Larynx; Keratosis of the Larynx; Laryngeal keratosis; Laryngeal Keratosis; Laryngeal leukoplakia; Laryngeal Leukoplakia; Laryngeal squamous cell hyperplasia
SNOMED CT:	Leukoplakia of larynx (73659001); Laryngeal leukoplakia (73659001); Laryngeal keratosis (73659001); Laryngeal squamous cell hyperplasia (73659001)

Definition

A premalignant pathologic process that affects the mucosal epithelium of the larynx. It appears as a localized or diffuse white patch on the laryngeal mucosa. Morphologically it is characterized by the pathologic production of keratin in the mucosal epithelial surface with or without epithelial atypia. It may progress to or co-exist with invasive squamous cell carcinoma. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVLeukoplakia of larynx

Pathological process
- Disease
  - Disorder by Site
    - Head and Neck Disorder
      - Head and Neck Precancerous Condition
        Laryngeal Precancerous Condition
        Leukoplakia of larynx
        Leukoplakia of Vocal Cords
        Interarytenoid Leukoplakia

Professional guidelines

PubMed

Vocal fold leukoplakia: incidence, management, and prevention.

Parker NP
Curr Opin Otolaryngol Head Neck Surg 2017 Dec;25(6):464-468. doi: 10.1097/MOO.0000000000000406. PMID: 28857841

Diagnostic evaluation and management of hoarseness.

Mau T
Med Clin North Am 2010 Sep;94(5):945-60. doi: 10.1016/j.mcna.2010.05.010. PMID: 20736105

Early detection, diagnosis, and management of oral and oropharyngeal cancer.

Mashberg A, Samit AM
CA Cancer J Clin 1989 Mar-Apr;39(2):67-88. doi: 10.3322/canjclin.39.2.67. PMID: 2495159

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