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Lymphocytic colitis

MedGen UID:
98006
Concept ID:
C0400822
Disease or Syndrome
Synonyms: Colitis, Lymphocytic; Lymphocytic Colitis
SNOMED CT: Lymphocytic colitis (1187071008)
 
Monarch Initiative: MONDO:0000704

Definition

Microscopic colitis characterized by the accumulation of lymphocytes in the colonic epithelium and lamina propria. Patients present with chronic watery diarrhea. Colonoscopy reveals normal colonic mucosa. The diagnosis is made with the microscopic examination of the colonic biopsy samples. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLymphocytic colitis
Follow this link to review classifications for Lymphocytic colitis in Orphanet.

Professional guidelines

PubMed

Rojo E, Casanova MJ, Gisbert JP
Rev Esp Enferm Dig 2020 Jan;112(1):53-58. doi: 10.17235/reed.2019.6655/2019. PMID: 31880163
Miehlke S, Verhaegh B, Tontini GE, Madisch A, Langner C, Münch A
Lancet Gastroenterol Hepatol 2019 Apr;4(4):305-314. doi: 10.1016/S2468-1253(19)30048-2. PMID: 30860066
Pardi DS
Am J Gastroenterol 2017 Jan;112(1):78-85. Epub 2016 Nov 29 doi: 10.1038/ajg.2016.477. PMID: 27897155

Recent clinical studies

Etiology

Garczyk A, Mardas M, Stelmach-Mardas M
Int J Mol Sci 2023 Apr 10;24(8) doi: 10.3390/ijms24087026. PMID: 37108189Free PMC Article
Yuan L, Wu TT, Zhang L
Hum Pathol 2023 Feb;132:89-101. Epub 2022 Jul 6 doi: 10.1016/j.humpath.2022.06.027. PMID: 35809686
Tome J, Kamboj AK, Pardi DS
Mayo Clin Proc 2021 May;96(5):1302-1308. doi: 10.1016/j.mayocp.2021.03.022. PMID: 33958059
Miehlke S, Verhaegh B, Tontini GE, Madisch A, Langner C, Münch A
Lancet Gastroenterol Hepatol 2019 Apr;4(4):305-314. doi: 10.1016/S2468-1253(19)30048-2. PMID: 30860066
Bouma G, Münch A
Dig Dis 2015;33(2):208-214. Epub 2015 Apr 22 doi: 10.1159/000369517. PMID: 25925924

Diagnosis

Yuan L, Wu TT, Zhang L
Hum Pathol 2023 Feb;132:89-101. Epub 2022 Jul 6 doi: 10.1016/j.humpath.2022.06.027. PMID: 35809686
Burke KE, D'Amato M, Ng SC, Pardi DS, Ludvigsson JF, Khalili H
Nat Rev Dis Primers 2021 Jun 10;7(1):39. doi: 10.1038/s41572-021-00273-2. PMID: 34112810
Tome J, Kamboj AK, Pardi DS
Mayo Clin Proc 2021 May;96(5):1302-1308. doi: 10.1016/j.mayocp.2021.03.022. PMID: 33958059
Miehlke S, Verhaegh B, Tontini GE, Madisch A, Langner C, Münch A
Lancet Gastroenterol Hepatol 2019 Apr;4(4):305-314. doi: 10.1016/S2468-1253(19)30048-2. PMID: 30860066
Bouma G, Münch A
Dig Dis 2015;33(2):208-214. Epub 2015 Apr 22 doi: 10.1159/000369517. PMID: 25925924

Therapy

Burke KE, D'Amato M, Ng SC, Pardi DS, Ludvigsson JF, Khalili H
Nat Rev Dis Primers 2021 Jun 10;7(1):39. doi: 10.1038/s41572-021-00273-2. PMID: 34112810
Tome J, Kamboj AK, Pardi DS
Mayo Clin Proc 2021 May;96(5):1302-1308. doi: 10.1016/j.mayocp.2021.03.022. PMID: 33958059
Rojo E, Casanova MJ, Gisbert JP
Rev Esp Enferm Dig 2020 Jan;112(1):53-58. doi: 10.17235/reed.2019.6655/2019. PMID: 31880163
Miehlke S, Verhaegh B, Tontini GE, Madisch A, Langner C, Münch A
Lancet Gastroenterol Hepatol 2019 Apr;4(4):305-314. doi: 10.1016/S2468-1253(19)30048-2. PMID: 30860066
Bouma G, Münch A
Dig Dis 2015;33(2):208-214. Epub 2015 Apr 22 doi: 10.1159/000369517. PMID: 25925924

Prognosis

Tome J, Kamboj AK, Pardi DS
Mayo Clin Proc 2021 May;96(5):1302-1308. doi: 10.1016/j.mayocp.2021.03.022. PMID: 33958059
Miehlke S, Verhaegh B, Tontini GE, Madisch A, Langner C, Münch A
Lancet Gastroenterol Hepatol 2019 Apr;4(4):305-314. doi: 10.1016/S2468-1253(19)30048-2. PMID: 30860066
Siakavellas SI, Bamias G
Curr Opin Gastroenterol 2018 Nov;34(6):377-383. doi: 10.1097/MOG.0000000000000482. PMID: 30157044
Bouma G, Münch A
Dig Dis 2015;33(2):208-214. Epub 2015 Apr 22 doi: 10.1159/000369517. PMID: 25925924
Rasmussen MA, Munck LK
Aliment Pharmacol Ther 2012 Jul;36(2):79-90. Epub 2012 Jun 3 doi: 10.1111/j.1365-2036.2012.05166.x. PMID: 22670660

Clinical prediction guides

Garczyk A, Mardas M, Stelmach-Mardas M
Int J Mol Sci 2023 Apr 10;24(8) doi: 10.3390/ijms24087026. PMID: 37108189Free PMC Article
Sonnenberg A, Genta RM
J Crohns Colitis 2022 Sep 8;16(9):1415-1419. doi: 10.1093/ecco-jcc/jjac046. PMID: 35301514
Rivière P, Münch A, Michetti P, Chande N, de Hertogh G, Schoeters P, Ferrante M, Vermeire S, Van Assche G
J Crohns Colitis 2019 Mar 26;13(3):337-340. doi: 10.1093/ecco-jcc/jjy169. PMID: 30329034
Law EH, Badowski M, Hung YT, Weems K, Sanchez A, Lee TA
Ann Pharmacother 2017 Mar;51(3):253-263. Epub 2016 Oct 13 doi: 10.1177/1060028016673859. PMID: 27733667
Tong J, Zheng Q, Zhang C, Lo R, Shen J, Ran Z
Am J Gastroenterol 2015 Feb;110(2):265-76; quiz 277. Epub 2015 Jan 27 doi: 10.1038/ajg.2014.431. PMID: 25623658

Recent systematic reviews

Zabana Y, Tontini G, Hultgren-Hörnquist E, Skonieczna-Żydecka K, Latella G, Østvik AE, Marlicz W, D'Amato M, Arias A, Mielhke S, Münch A, Fernández-Bañares F, Lucendo AJ
J Crohns Colitis 2022 Jan 28;16(1):143-161. doi: 10.1093/ecco-jcc/jjab123. PMID: 34272945
Marlicz W, Skonieczna-Żydecka K, Yung DE, Loniewski I, Koulaouzidis A
Dig Liver Dis 2017 Oct;49(10):1073-1085. Epub 2017 Aug 9 doi: 10.1016/j.dld.2017.07.015. PMID: 28847471
Kamp EJ, Kane JS, Ford AC
Clin Gastroenterol Hepatol 2016 May;14(5):659-68.e1; quiz e54-5. Epub 2015 Nov 19 doi: 10.1016/j.cgh.2015.09.031. PMID: 26453949
Tong J, Zheng Q, Zhang C, Lo R, Shen J, Ran Z
Am J Gastroenterol 2015 Feb;110(2):265-76; quiz 277. Epub 2015 Jan 27 doi: 10.1038/ajg.2014.431. PMID: 25623658
Rasmussen MA, Munck LK
Aliment Pharmacol Ther 2012 Jul;36(2):79-90. Epub 2012 Jun 3 doi: 10.1111/j.1365-2036.2012.05166.x. PMID: 22670660

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