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Acromelanosis

MedGen UID:
98038
Concept ID:
C0406779
Congenital Abnormality
Synonym: Progressive acromelanosis
SNOMED CT: Acromelanosis (239089006)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
Concept ID:
CN307042
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
 
Monarch Initiative: MONDO:0018311
Orphanet: ORPHA39

Definition

A rare pigmentation anomaly of the skin characterized by otherwise asymptomatic hyperpigmentation of the skin over the dorsal side of fingers and toes which may rapidly spread towards proximal regions, like genitals, abdomen, and thighs. It is mostly seen in newborns or during the first years of life. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcromelanosis
Follow this link to review classifications for Acromelanosis in Orphanet.

Recent clinical studies

Etiology

González JR, Vázquez Botet M
J Am Acad Dermatol 1980 Feb;2(2):128-31. doi: 10.1016/s0190-9622(80)80391-4. PMID: 7364970

Diagnosis

Arnold AW, Kern JS, Itin PH, Pigors M, Happle R, Has C
Dermatology 2012;224(4):331-9. Epub 2012 Jun 19 doi: 10.1159/000339328. PMID: 22722384
González JR, Vázquez Botet M
J Am Acad Dermatol 1980 Feb;2(2):128-31. doi: 10.1016/s0190-9622(80)80391-4. PMID: 7364970
SIEMENS HW
Dermatologica 1964;128:86-7. doi: 10.1159/000254726. PMID: 14111908

Prognosis

González JR, Vázquez Botet M
J Am Acad Dermatol 1980 Feb;2(2):128-31. doi: 10.1016/s0190-9622(80)80391-4. PMID: 7364970

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