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Lupus vulgaris

MedGen UID:: 9821
•Concept ID:: C0024131
•: Disease or Syndrome

Synonym:	Lupus Vulgaris
SNOMED CT:	LV - Lupus vulgaris (10528009); Tuberculosis lupus exedens (10528009); Tuberculosis luposa cutis (10528009); Lupus vulgaris (10528009); Lupus exedens (10528009); Tuberculosis cutis luposa (10528009)

Monarch Initiative:	MONDO:0006838

Definition

A form of cutaneous tuberculosis. It is seen predominantly in women and typically involves the nasal mucosa; buccal mucosa; and conjunctival mucosa. [from MONDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVLupus vulgaris

Finding by Cause
- Infection
  - Bacterial Infections and Mycoses
    - Bacterial infectious disease
      - Bacterial infection of skin
        Cutaneous tuberculosis
        Lupus vulgaris

Professional guidelines

PubMed

Cutaneous tuberculosis. Part II: Complications, diagnostic workup, histopathologic features, and treatment.

Kaul S, Jakhar D, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1107-1119. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.064. PMID: 35149148

Niels Finsen's treatment for lupus vulgaris.

Gøtzsche PC
J R Soc Med 2011 Jan;104(1):41-2. doi: 10.1258/jrsm.2010.10k066. PMID: 21205777 Free PMC Article

The treatment of lupus vulgaris.

THORNE NA
Br J Clin Pract 1958 Jun;12(6):391-5. PMID: 13536238

See all (14)

Recent clinical studies

Etiology

Twenty-nine cases of lupus vulgaris.

Sellami K, Boudaya S, Chaabane H, Amouri M, Masmoudi A, Mseddi M, Turki H
Med Mal Infect 2016 Mar;46(2):93-5. Epub 2016 Jan 18 doi: 10.1016/j.medmal.2015.12.007. PMID: 26794085

Adalimumab: a review of side effects.

Scheinfeld N
Expert Opin Drug Saf 2005 Jul;4(4):637-41. doi: 10.1517/14740338.4.4.637. PMID: 16011443

Earlobe dermatitis.

Ozkaya-Bayazit E, Baykal C, Büyükbabani N, Hafiz G
Arch Dermatol 2002 Dec;138(12):1607-12. doi: 10.1001/archderm.138.12.1607. PMID: 12472356

Simvastatin-induced lupus-like syndrome.

Ahmad A, Fletcher MT, Roy TM
Tenn Med 2000 Jan;93(1):21-2. PMID: 10628262

Neonatal lupus.

Buyon JP
Curr Opin Rheumatol 1996 Sep;8(5):485-90. doi: 10.1097/00002281-199609000-00016. PMID: 8941454

See all (130)

Diagnosis

Cutaneous tuberculosis. Part I: Pathogenesis, classification, and clinical features.

Kaul S, Kaur I, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1091-1103. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.063. PMID: 35149149

Cutaneous tuberculosis. Part II: Complications, diagnostic workup, histopathologic features, and treatment.

Kaul S, Jakhar D, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1107-1119. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.064. PMID: 35149148

The history of lupus throughout the ages.

Felten R, Lipsker D, Sibilia J, Chasset F, Arnaud L
J Am Acad Dermatol 2022 Dec;87(6):1361-1369. Epub 2020 May 4 doi: 10.1016/j.jaad.2020.04.150. PMID: 32380218

Dermatoscopy of Granulomatous Disorders.

Errichetti E, Stinco G
Dermatol Clin 2018 Oct;36(4):369-375. Epub 2018 Aug 2 doi: 10.1016/j.det.2018.05.004. PMID: 30201146

Lupus nephritis.

Donadio JV Jr, Holley KE
Minn Med 1975 Jan;58(1):43-8. PMID: 45866

See all (358)

Therapy

Lupus vulgaris of the left breast.

Chen T, Ma DL
Lancet Infect Dis 2023 Apr;23(4):508. doi: 10.1016/S1473-3099(22)00758-7. PMID: 36963919

Cutaneous tuberculosis. Part II: Complications, diagnostic workup, histopathologic features, and treatment.

Kaul S, Jakhar D, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1107-1119. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.064. PMID: 35149148

The history of lupus throughout the ages.

Felten R, Lipsker D, Sibilia J, Chasset F, Arnaud L
J Am Acad Dermatol 2022 Dec;87(6):1361-1369. Epub 2020 May 4 doi: 10.1016/j.jaad.2020.04.150. PMID: 32380218

Antithyroid drugs.

Cooper DS
N Engl J Med 1984 Nov 22;311(21):1353-62. doi: 10.1056/NEJM198411223112106. PMID: 6387489

Lupus nephritis.

Donadio JV Jr, Holley KE
Minn Med 1975 Jan;58(1):43-8. PMID: 45866

See all (290)

Prognosis

Chronic cutaneous lesions of sarcoidosis.

Marchell RM, Judson MA
Clin Dermatol 2007 May-Jun;25(3):295-302. doi: 10.1016/j.clindermatol.2007.03.007. PMID: 17560307

Toxicity of infliximab in the course of treatment of Crohn's disease.

Bratcher JM, Korelitz BI
Expert Opin Drug Saf 2006 Jan;5(1):9-16. doi: 10.1517/14740338.5.1.9. PMID: 16370952

Earlobe dermatitis.

Ozkaya-Bayazit E, Baykal C, Büyükbabani N, Hafiz G
Arch Dermatol 2002 Dec;138(12):1607-12. doi: 10.1001/archderm.138.12.1607. PMID: 12472356

Mesalazine-induced lupus.

Timsit MA, Anglicheau D, Lioté F, Marteau P, Dryll A
Rev Rhum Engl Ed 1997 Oct;64(10):586-8. PMID: 9385697

Penile lupus vulgaris.

Jaisankar TJ, Garg BR, Reddy BS, Riba B, Ramarao AP
Int J Dermatol 1994 Apr;33(4):272-4. doi: 10.1111/j.1365-4362.1994.tb01043.x. PMID: 8021086

See all (86)

Clinical prediction guides

Autoimmune-mediated congenital heart block.

Wainwright B, Bhan R, Trad C, Cohen R, Saxena A, Buyon J, Izmirly P
Best Pract Res Clin Obstet Gynaecol 2020 Apr;64:41-51. Epub 2019 Oct 8 doi: 10.1016/j.bpobgyn.2019.09.001. PMID: 31685414

The therapeutic potential of tumor necrosis factor for autoimmune disease: a mechanistically based hypothesis.

Kodama S, Davis M, Faustman DL
Cell Mol Life Sci 2005 Aug;62(16):1850-62. doi: 10.1007/s00018-005-5022-6. PMID: 15968469 Free PMC Article

Neonatal lupus.

Brucato A, Cimaz R, Stramba-Badiale M
Clin Rev Allergy Immunol 2002 Dec;23(3):279-99. doi: 10.1385/CRIAI:23:3:279. PMID: 12402413

Antibodies to histones in systemic lupus erythematosus and drug-induced lupus syndromes.

Monestier M, Kotzin BL
Rheum Dis Clin North Am 1992 May;18(2):415-36. PMID: 1626076

Lupus pernio.

James DG
Lupus 1992 May;1(3):129-31. doi: 10.1177/096120339200100302. PMID: 1301972

See all (74)