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Lymphoid system disorder

MedGen UID:
9829
•Concept ID:
C0024228
•
Disease or Syndrome
Synonym: Lymphoid system disease
SNOMED CT: Disorder of lymphoid system (111590001); Disorders of lymph node and lymphatics (234087005); Disorder of lymphatic system (362971004); Disorder of lymphatics (3305006); Lymphangiopathy (3305006)
 
Monarch Initiative: MONDO:0044986

Definition

A disease or disorder that involves the lymphoid system. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLymphoid system disorder

Professional guidelines

PubMed

Pathobiology and treatment of lymphomatoid granulomatosis, a rare EBV-driven disorder.
Melani C, Jaffe ES, Wilson WH
Blood 2020 Apr 16;135(16):1344-1352. doi: 10.1182/blood.2019000933. PMID: 32107539Free PMC Article
International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017).
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K, Gribben J, Pfreunschuh M, Morschhauser F, Schoder H, Zelenetz AD, Rademaker J, Advani R, Valente N, Fortpied C, Witzig TE, Sehn LH, Engert A, Fisher RI, Zinzani PL, Federico M, Hutchings M, Bollard C, Trneny M, Elsayed YA, Tobinai K, Abramson JS, Fowler N, Goy A, Smith M, Ansell S, Kuruvilla J, Dreyling M, Thieblemont C, Little RF, Aurer I, Van Oers MHJ, Takeshita K, Gopal A, Rule S, de Vos S, Kloos I, Kaminski MS, Meignan M, Schwartz LH, Leonard JP, Schuster SJ, Seshan VE
Ann Oncol 2017 Jul 1;28(7):1436-1447. doi: 10.1093/annonc/mdx097. PMID: 28379322Free PMC Article
Non-Hodgkin Lymphoma: Diagnosis and Treatment.
Ansell SM
Mayo Clin Proc 2015 Aug;90(8):1152-63. doi: 10.1016/j.mayocp.2015.04.025. PMID: 26250731

Recent clinical studies

Etiology

The International Consensus Classification (ICC) of hematologic neoplasms with germline predisposition, pediatric myelodysplastic syndrome, and juvenile myelomonocytic leukemia.
Rudelius M, Weinberg OK, Niemeyer CM, Shimamura A, Calvo KR
Virchows Arch 2023 Jan;482(1):113-130. Epub 2022 Nov 29 doi: 10.1007/s00428-022-03447-9. PMID: 36445482
Ankylosing spondylitis: an autoimmune or autoinflammatory disease?
Mauro D, Thomas R, Guggino G, Lories R, Brown MA, Ciccia F
Nat Rev Rheumatol 2021 Jul;17(7):387-404. Epub 2021 Jun 10 doi: 10.1038/s41584-021-00625-y. PMID: 34113018
Impact of Obesity and Metabolic Syndrome on Immunity.
Andersen CJ, Murphy KE, Fernandez ML
Adv Nutr 2016 Jan;7(1):66-75. Epub 2016 Jan 15 doi: 10.3945/an.115.010207. PMID: 26773015Free PMC Article
The immunology of Epstein-Barr virus-induced disease.
Taylor GS, Long HM, Brooks JM, Rickinson AB, Hislop AD
Annu Rev Immunol 2015;33:787-821. Epub 2015 Feb 11 doi: 10.1146/annurev-immunol-032414-112326. PMID: 25706097
Immunopathology of inflammatory bowel disease.
Wallace KL, Zheng LB, Kanazawa Y, Shih DQ
World J Gastroenterol 2014 Jan 7;20(1):6-21. doi: 10.3748/wjg.v20.i1.6. PMID: 24415853Free PMC Article

Diagnosis

The International Consensus Classification (ICC) of hematologic neoplasms with germline predisposition, pediatric myelodysplastic syndrome, and juvenile myelomonocytic leukemia.
Rudelius M, Weinberg OK, Niemeyer CM, Shimamura A, Calvo KR
Virchows Arch 2023 Jan;482(1):113-130. Epub 2022 Nov 29 doi: 10.1007/s00428-022-03447-9. PMID: 36445482
Diagnosis and classification of lymphoma: Impact of technical advances.
Jaffe ES
Semin Hematol 2019 Jan;56(1):30-36. Epub 2018 May 29 doi: 10.1053/j.seminhematol.2018.05.007. PMID: 30573042Free PMC Article
Gut microbiota and Hashimoto's thyroiditis.
Virili C, Fallahi P, Antonelli A, Benvenga S, Centanni M
Rev Endocr Metab Disord 2018 Dec;19(4):293-300. doi: 10.1007/s11154-018-9467-y. PMID: 30294759
Autophagy and Inflammation.
Matsuzawa-Ishimoto Y, Hwang S, Cadwell K
Annu Rev Immunol 2018 Apr 26;36:73-101. Epub 2017 Nov 16 doi: 10.1146/annurev-immunol-042617-053253. PMID: 29144836
Non-Hodgkin Lymphoma: Diagnosis and Treatment.
Ansell SM
Mayo Clin Proc 2015 Aug;90(8):1152-63. doi: 10.1016/j.mayocp.2015.04.025. PMID: 26250731

Therapy

Engineering the next generation of CAR-NK immunotherapies.
Biederstädt A, Rezvani K
Int J Hematol 2021 Nov;114(5):554-571. Epub 2021 Aug 28 doi: 10.1007/s12185-021-03209-4. PMID: 34453686Free PMC Article
Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study.
Perry BI, Upthegrove R, Kappelmann N, Jones PB, Burgess S, Khandaker GM
Brain Behav Immun 2021 Oct;97:176-185. Epub 2021 Jul 16 doi: 10.1016/j.bbi.2021.07.009. PMID: 34280516Free PMC Article
Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway: Therapeutic Targets in Autoimmunity and Inflammation.
Tsai HC, Han MH
Drugs 2016 Jul;76(11):1067-79. doi: 10.1007/s40265-016-0603-2. PMID: 27318702
Post-transplant lymphoproliferative disease (PTLD): risk factors, diagnosis, and current treatment strategies.
Al-Mansour Z, Nelson BP, Evens AM
Curr Hematol Malig Rep 2013 Sep;8(3):173-83. doi: 10.1007/s11899-013-0162-5. PMID: 23737188Free PMC Article
Adenosine deaminase: functional implications and different classes of inhibitors.
Cristalli G, Costanzi S, Lambertucci C, Lupidi G, Vittori S, Volpini R, Camaioni E
Med Res Rev 2001 Mar;21(2):105-28. doi: 10.1002/1098-1128(200103)21:2<105::aid-med1002>3.0.co;2-u. PMID: 11223861

Prognosis

International Consensus Classification of myeloid and lymphoid neoplasms: myeloproliferative neoplasms.
Gianelli U, Thiele J, Orazi A, Gangat N, Vannucchi AM, Tefferi A, Kvasnicka HM
Virchows Arch 2023 Jan;482(1):53-68. Epub 2022 Dec 29 doi: 10.1007/s00428-022-03480-8. PMID: 36580136Free PMC Article
Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study.
Perry BI, Upthegrove R, Kappelmann N, Jones PB, Burgess S, Khandaker GM
Brain Behav Immun 2021 Oct;97:176-185. Epub 2021 Jul 16 doi: 10.1016/j.bbi.2021.07.009. PMID: 34280516Free PMC Article
Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.
Allemani C, Matsuda T, Di Carlo V, Harewood R, Matz M, Nikšić M, Bonaventure A, Valkov M, Johnson CJ, Estève J, Ogunbiyi OJ, Azevedo E Silva G, Chen WQ, Eser S, Engholm G, Stiller CA, Monnereau A, Woods RR, Visser O, Lim GH, Aitken J, Weir HK, Coleman MP; CONCORD Working Group
Lancet 2018 Mar 17;391(10125):1023-1075. Epub 2018 Jan 31 doi: 10.1016/S0140-6736(17)33326-3. PMID: 29395269Free PMC Article
Lymphoma classification update: T-cell lymphomas, Hodgkin lymphomas, and histiocytic/dendritic cell neoplasms.
Jiang M, Bennani NN, Feldman AL
Expert Rev Hematol 2017 Mar;10(3):239-249. Epub 2017 Jan 29 doi: 10.1080/17474086.2017.1281122. PMID: 28133975Free PMC Article
Non-Hodgkin Lymphoma: Diagnosis and Treatment.
Ansell SM
Mayo Clin Proc 2015 Aug;90(8):1152-63. doi: 10.1016/j.mayocp.2015.04.025. PMID: 26250731

Clinical prediction guides

Clonal haematopoiesis and dysregulation of the immune system.
Belizaire R, Wong WJ, Robinette ML, Ebert BL
Nat Rev Immunol 2023 Sep;23(9):595-610. Epub 2023 Mar 20 doi: 10.1038/s41577-023-00843-3. PMID: 36941354
Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study.
Perry BI, Upthegrove R, Kappelmann N, Jones PB, Burgess S, Khandaker GM
Brain Behav Immun 2021 Oct;97:176-185. Epub 2021 Jul 16 doi: 10.1016/j.bbi.2021.07.009. PMID: 34280516Free PMC Article
Lymphadenopathy at the crossroad between immunodeficiency and autoinflammation: An intriguing challenge.
Costagliola G, Consolini R
Clin Exp Immunol 2021 Sep;205(3):288-305. Epub 2021 Jun 20 doi: 10.1111/cei.13620. PMID: 34008169Free PMC Article
Tumor-Infiltrating Lymphocytes and Their Prognostic Value in Cutaneous Melanoma.
Maibach F, Sadozai H, Seyed Jafari SM, Hunger RE, Schenk M
Front Immunol 2020;11:2105. Epub 2020 Sep 10 doi: 10.3389/fimmu.2020.02105. PMID: 33013886Free PMC Article
International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017).
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K, Gribben J, Pfreunschuh M, Morschhauser F, Schoder H, Zelenetz AD, Rademaker J, Advani R, Valente N, Fortpied C, Witzig TE, Sehn LH, Engert A, Fisher RI, Zinzani PL, Federico M, Hutchings M, Bollard C, Trneny M, Elsayed YA, Tobinai K, Abramson JS, Fowler N, Goy A, Smith M, Ansell S, Kuruvilla J, Dreyling M, Thieblemont C, Little RF, Aurer I, Van Oers MHJ, Takeshita K, Gopal A, Rule S, de Vos S, Kloos I, Kaminski MS, Meignan M, Schwartz LH, Leonard JP, Schuster SJ, Seshan VE
Ann Oncol 2017 Jul 1;28(7):1436-1447. doi: 10.1093/annonc/mdx097. PMID: 28379322Free PMC Article

Recent systematic reviews

Prognostic value of tertiary lymphoid structures (TLS) in digestive system cancers: a systematic review and meta-analysis.
Sun H, Shi Y, Ran H, Peng J, Li Q, Zheng G, He Y, Liu S, Chang W, Xiao Y
BMC Cancer 2023 Dec 18;23(1):1248. doi: 10.1186/s12885-023-11738-w. PMID: 38110876Free PMC Article
Treatment strategies for Sjögren's syndrome with childhood onset: a systematic review of the literature.
Doolan G, Faizal NM, Foley C, Al-Obaidi M, Jury EC, Price E, Ramanan AV, Lieberman SM, Ciurtin C
Rheumatology (Oxford) 2022 Mar 2;61(3):892-912. doi: 10.1093/rheumatology/keab579. PMID: 34289032Free PMC Article
International consensus to standardise histopathological scoring for small bowel strictures in Crohn's disease.
Gordon IO, Bettenworth D, Bokemeyer A, Srivastava A, Rosty C, de Hertogh G, Robert ME, Valasek MA, Mao R, Li J, Harpaz N, Borralho P, Pai RK, Odze R, Feakins R, Parker CE, Guizzetti L, Nguyen T, Shackelton LM, Sandborn WJ, Jairath V, Baker M, Bruining D, Fletcher JG, Feagan BG, Pai RK, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium
Gut 2022 Mar;71(3):479-486. Epub 2021 May 5 doi: 10.1136/gutjnl-2021-324374. PMID: 33952604Free PMC Article
A Systematic Approach to the Cutaneous Lymphoid Infiltrates: A Clinical, Morphologic, and Immunophenotypic Evaluation.
Gru AA, McHargue C, Salavaggione AL
Arch Pathol Lab Med 2019 Aug;143(8):958-979. doi: 10.5858/arpa.2018-0294-RA. PMID: 31339758
Rituximab, fludarabine, and cyclophosphamide versus fludarabine and cyclophosphamide for treatment of chronic lymphocytic leukemia: A systematic review with meta-analysis.
Nunes AA, da Silva AS, Souza KM, Koury Cde N, de Mello LM
Crit Rev Oncol Hematol 2015 Jun;94(3):261-9. Epub 2015 Mar 11 doi: 10.1016/j.critrevonc.2015.02.013. PMID: 25797826

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