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Granulomatous mastitis

MedGen UID:
98343
Concept ID:
C0405469
Disease or Syndrome
Synonyms: Granulomatous Mastitis; Mastitis, Granulomatous
SNOMED CT: Granulomatous mastitis (237444008)
 
Monarch Initiative: MONDO:0018987
Orphanet: ORPHA64722

Definition

A rare gynecologic or obstetric disease characterized by a painful, palpable breast mass with relative sparing of the subareolar regions, often associated with inflammation of the overlying skin and accompanied by axillary lymphadenopathy. It usually occurs in young parous women with a history of breast-feeding. The diagnosis of idiopathic granulomatous mastitis requires that other granulomatous lesions in the breast be excluded. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGranulomatous mastitis
Follow this link to review classifications for Granulomatous mastitis in Orphanet.

Professional guidelines

PubMed

Yuan QQ, Xiao SY, Farouk O, Du YT, Sheybani F, Tan QT, Akbulut S, Cetin K, Alikhassi A, Yaghan RJ, Durur-Subasi I, Altintoprak F, Eom TI, Alper F, Hasbahceci M, Martínez-Ramos D, Oztekin PS, Kwong A, Pluguez-Turull CW, Brownson KE, Chandanwale S, Habibi M, Lan LY, Zhou R, Zeng XT, Bai J, Bai JW, Chen QR, Chen X, Zha XM, Dai WJ, Dai ZJ, Feng QY, Gao QJ, Gao RF, Han BS, Hou JX, Hou W, Liao HY, Luo H, Liu ZR, Lu JH, Luo B, Ma XP, Qian J, Qin JY, Wei W, Wei G, Xu LY, Xue HC, Yang HW, Yang WG, Zhang CJ, Zhang F, Zhang GX, Zhang SK, Zhang SQ, Zhang YQ, Zhang YP, Zhang SC, Zhao DW, Zheng XM, Zheng LW, Xu GR, Zhou WB, Wu GS
Mil Med Res 2022 Apr 26;9(1):20. doi: 10.1186/s40779-022-00380-5. PMID: 35473758Free PMC Article
Yin Y, Liu X, Meng Q, Han X, Zhang H, Lv Y
J Invest Surg 2022 Mar;35(3):709-720. Epub 2021 Mar 10 doi: 10.1080/08941939.2021.1894516. PMID: 33691563
Angelopoulou A, Field D, Ryan CA, Stanton C, Hill C, Ross RP
Med Microbiol Immunol 2018 Apr;207(2):83-94. Epub 2018 Jan 19 doi: 10.1007/s00430-017-0532-z. PMID: 29350290

Recent clinical studies

Etiology

Dilaveri C, Degnim A, Lee C, DeSimone D, Moldoveanu D, Ghosh K
Breast J 2024;2024:6693720. Epub 2024 Jan 25 doi: 10.1155/2024/6693720. PMID: 38304866Free PMC Article
Ramadan R, Koryem IM, Fayed H
Breast Dis 2022;41(1):413-420. doi: 10.3233/BD-220047. PMID: 36530069
Cakir C, Nayci AE, Ferlengez E, Guler M, Idiz UO
J Coll Physicians Surg Pak 2022 Jul;32(7):869-873. doi: 10.29271/jcpsp.2022.07.869. PMID: 35795934
Pala EE, Ekmekci S, Kilic M, Dursun A, Colakoglu G, Karaali C, Emiroglu M, Emiroglu M
Turk Patoloji Derg 2022;38(1):40-45. doi: 10.5146/tjpath.2021.01554. PMID: 34558655Free PMC Article
Mahlab-Guri K, Asher I, Allweis T, Diment J, Sthoeger ZM, Mavor E
Isr Med Assoc J 2015 Aug;17(8):476-80. PMID: 26394488

Diagnosis

Yuan QQ, Xiao SY, Farouk O, Du YT, Sheybani F, Tan QT, Akbulut S, Cetin K, Alikhassi A, Yaghan RJ, Durur-Subasi I, Altintoprak F, Eom TI, Alper F, Hasbahceci M, Martínez-Ramos D, Oztekin PS, Kwong A, Pluguez-Turull CW, Brownson KE, Chandanwale S, Habibi M, Lan LY, Zhou R, Zeng XT, Bai J, Bai JW, Chen QR, Chen X, Zha XM, Dai WJ, Dai ZJ, Feng QY, Gao QJ, Gao RF, Han BS, Hou JX, Hou W, Liao HY, Luo H, Liu ZR, Lu JH, Luo B, Ma XP, Qian J, Qin JY, Wei W, Wei G, Xu LY, Xue HC, Yang HW, Yang WG, Zhang CJ, Zhang F, Zhang GX, Zhang SK, Zhang SQ, Zhang YQ, Zhang YP, Zhang SC, Zhao DW, Zheng XM, Zheng LW, Xu GR, Zhou WB, Wu GS
Mil Med Res 2022 Apr 26;9(1):20. doi: 10.1186/s40779-022-00380-5. PMID: 35473758Free PMC Article
Scott DM
Best Pract Res Clin Obstet Gynaecol 2022 Sep;83:72-87. Epub 2021 Dec 8 doi: 10.1016/j.bpobgyn.2021.11.013. PMID: 34991976
Yin Y, Liu X, Meng Q, Han X, Zhang H, Lv Y
J Invest Surg 2022 Mar;35(3):709-720. Epub 2021 Mar 10 doi: 10.1080/08941939.2021.1894516. PMID: 33691563
Coombe RF, Hamed H
Br J Hosp Med (Lond) 2021 May 2;82(5):1-7. Epub 2021 May 7 doi: 10.12968/hmed.2020.0718. PMID: 34076525
Omranipour R, Vasigh M
Adv Exp Med Biol 2020;1252:53-61. doi: 10.1007/978-3-030-41596-9_7. PMID: 32816262

Therapy

Azzam MI, Alnaimat F, Al-Nazer MW, Awad H, Odeh G, Al-Najar M, Alsayed S, El-Asir L, Addasi R, Melhem JM, Sweiss NJ
Rheumatol Int 2023 Oct;43(10):1859-1869. Epub 2023 Jun 22 doi: 10.1007/s00296-023-05375-6. PMID: 37347273
Coombe RF, Hamed H
Br J Hosp Med (Lond) 2021 May 2;82(5):1-7. Epub 2021 May 7 doi: 10.12968/hmed.2020.0718. PMID: 34076525
Angelopoulou A, Field D, Ryan CA, Stanton C, Hill C, Ross RP
Med Microbiol Immunol 2018 Apr;207(2):83-94. Epub 2018 Jan 19 doi: 10.1007/s00430-017-0532-z. PMID: 29350290
Mahlab-Guri K, Asher I, Allweis T, Diment J, Sthoeger ZM, Mavor E
Isr Med Assoc J 2015 Aug;17(8):476-80. PMID: 26394488
Diesing D, Axt-Fliedner R, Hornung D, Weiss JM, Diedrich K, Friedrich M
Arch Gynecol Obstet 2004 May;269(4):233-6. Epub 2003 Dec 19 doi: 10.1007/s00404-003-0561-2. PMID: 15205978

Prognosis

Dilaveri C, Degnim A, Lee C, DeSimone D, Moldoveanu D, Ghosh K
Breast J 2024;2024:6693720. Epub 2024 Jan 25 doi: 10.1155/2024/6693720. PMID: 38304866Free PMC Article
Azzam MI, Alnaimat F, Al-Nazer MW, Awad H, Odeh G, Al-Najar M, Alsayed S, El-Asir L, Addasi R, Melhem JM, Sweiss NJ
Rheumatol Int 2023 Oct;43(10):1859-1869. Epub 2023 Jun 22 doi: 10.1007/s00296-023-05375-6. PMID: 37347273
Faguy K
Radiol Technol 2018 Jan;89(3):279M-295M. PMID: 29298955
Mahlab-Guri K, Asher I, Allweis T, Diment J, Sthoeger ZM, Mavor E
Isr Med Assoc J 2015 Aug;17(8):476-80. PMID: 26394488
Pereira FA, Mudgil AV, Macias ES, Karsif K
Int J Dermatol 2012 Feb;51(2):142-51. doi: 10.1111/j.1365-4632.2011.05168.x. PMID: 22250621

Clinical prediction guides

Dilaveri C, Degnim A, Lee C, DeSimone D, Moldoveanu D, Ghosh K
Breast J 2024;2024:6693720. Epub 2024 Jan 25 doi: 10.1155/2024/6693720. PMID: 38304866Free PMC Article
Pala EE, Ekmekci S, Kilic M, Dursun A, Colakoglu G, Karaali C, Emiroglu M, Emiroglu M
Turk Patoloji Derg 2022;38(1):40-45. doi: 10.5146/tjpath.2021.01554. PMID: 34558655Free PMC Article
Yin Y, Liu X, Meng Q, Han X, Zhang H, Lv Y
J Invest Surg 2022 Mar;35(3):709-720. Epub 2021 Mar 10 doi: 10.1080/08941939.2021.1894516. PMID: 33691563
Nguyen MH, Molland JG, Kennedy S, Gray TJ, Limaye S
Intern Med J 2021 Nov;51(11):1791-1797. Epub 2021 Oct 29 doi: 10.1111/imj.15112. PMID: 34713960
Barreto DS, Sedgwick EL, Nagi CS, Benveniste AP
Breast Cancer Res Treat 2018 Oct;171(3):527-534. Epub 2018 Jul 3 doi: 10.1007/s10549-018-4870-3. PMID: 29971624

Recent systematic reviews

Fattahi AS, Amini G, Sajedi F, Mehrad-Majd H
Breast J 2023;2023:9947797. Epub 2023 Sep 26 doi: 10.1155/2023/9947797. PMID: 37794976Free PMC Article
Godazandeh G, Shojaee L, Alizadeh-Navaei R, Hessami A
Surg Today 2021 Dec;51(12):1897-1905. Epub 2021 Feb 15 doi: 10.1007/s00595-021-02234-4. PMID: 33590327
Martinez-Ramos D, Simon-Monterde L, Suelves-Piqueres C, Queralt-Martin R, Granel-Villach L, Laguna-Sastre JM, Nicolau MJ, Escrig-Sos J
Breast J 2019 Nov;25(6):1245-1250. Epub 2019 Jul 4 doi: 10.1111/tbj.13446. PMID: 31273861
Lei X, Chen K, Zhu L, Song E, Su F, Li S
Breastfeed Med 2017 Sep;12(7):415-421. Epub 2017 Jul 21 doi: 10.1089/bfm.2017.0030. PMID: 28731822
Rajagopala S, Agarwal R
Am J Med 2008 Jun;121(6):539-44. doi: 10.1016/j.amjmed.2008.01.026. PMID: 18501237

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