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Myeloid/lymphoid neoplasm associated with JAK2 rearrangement

MedGen UID:
986934
Concept ID:
CN305447
Disease or Syndrome
Synonyms: myeloid/lymphoid neoplasm associated with JAK2 rearrangement; myeloid/lymphoid neoplasms with PCM1-JAK2; Myeloid/lymphoid neoplasms with PCM1-JAK2
 
Monarch Initiative: MONDO:0035121
Orphanet: ORPHA589542

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMyeloid/lymphoid neoplasm associated with JAK2 rearrangement

Professional guidelines

PubMed

Zhang L, Shah B, Zhang Y, Tashkandi H, Xiao W, Fernandez-Pol S, Vergara-Lluri M, Hussaini M, Song J, Lancet J, Moscinski L, Yun S, Lu CM, Medeiros LJ, Tang G
Hum Pathol 2023 Jun;136:1-15. Epub 2023 Mar 22 doi: 10.1016/j.humpath.2023.03.002. PMID: 36958463
Shomali W, Gotlib J
Am J Hematol 2019 Oct;94(10):1149-1167. doi: 10.1002/ajh.25617. PMID: 31423623
Gotlib J
Am J Hematol 2017 Nov;92(11):1243-1259. doi: 10.1002/ajh.24880. PMID: 29044676

Recent clinical studies

Etiology

Saft L, Kvasnicka HM, Boudova L, Gianelli U, Lazzi S, Rozman M
Histopathology 2023 Dec;83(6):829-849. Epub 2023 Aug 8 doi: 10.1111/his.15021. PMID: 37551450
Tang G, Tam W, Short NJ, Bose P, Wu D, Hurwitz SN, Bagg A, Rogers HJ, Hsi ED, Quesada AE, Wang W, Miranda RN, Bueso-Ramos CE, Medeiros LJ, Nardi V, Hasserjian RP, Arber DA, Orazi A, Foucar K, Wang SA
Mod Pathol 2021 Sep;34(9):1673-1685. Epub 2021 May 14 doi: 10.1038/s41379-021-00817-7. PMID: 33990705
Shomali W, Gotlib J
Am J Hematol 2019 Oct;94(10):1149-1167. doi: 10.1002/ajh.25617. PMID: 31423623
Reiter A, Gotlib J
Blood 2017 Feb 9;129(6):704-714. Epub 2016 Dec 27 doi: 10.1182/blood-2016-10-695973. PMID: 28028030
Harrison CJ
Hematology Am Soc Hematol Educ Program 2013;2013:118-25. doi: 10.1182/asheducation-2013.1.118. PMID: 24319172

Diagnosis

Tzankov A, Reichard KK, Hasserjian RP, Arber DA, Orazi A, Wang SA
Virchows Arch 2023 Jan;482(1):85-97. Epub 2022 Sep 7 doi: 10.1007/s00428-022-03402-8. PMID: 36068374
Pozdnyakova O, Orazi A, Kelemen K, King R, Reichard KK, Craig FE, Quintanilla-Martinez L, Rimsza L, George TI, Horny HP, Wang SA
Am J Clin Pathol 2021 Feb 4;155(2):160-178. doi: 10.1093/ajcp/aqaa208. PMID: 33367495
Shomali W, Gotlib J
Am J Hematol 2019 Oct;94(10):1149-1167. doi: 10.1002/ajh.25617. PMID: 31423623
Tang G, Sydney Sir Philip JK, Weinberg O, Tam W, Sadigh S, Lake JI, Margolskee EM, Rogers HJ, Miranda RN, Bueso-Ramos C C, Hsi ED, Orazi A, Hasserjian RP, Arber DA, Bagg A, Wang SA
Mod Pathol 2019 Apr;32(4):490-498. Epub 2018 Nov 6 doi: 10.1038/s41379-018-0165-9. PMID: 30401948
Reiter A, Gotlib J
Blood 2017 Feb 9;129(6):704-714. Epub 2016 Dec 27 doi: 10.1182/blood-2016-10-695973. PMID: 28028030

Therapy

Shomali W, Gotlib J
Am J Hematol 2019 Oct;94(10):1149-1167. doi: 10.1002/ajh.25617. PMID: 31423623
Reiter A, Gotlib J
Blood 2017 Feb 9;129(6):704-714. Epub 2016 Dec 27 doi: 10.1182/blood-2016-10-695973. PMID: 28028030

Prognosis

Zhang L, Shah B, Zhang Y, Tashkandi H, Xiao W, Fernandez-Pol S, Vergara-Lluri M, Hussaini M, Song J, Lancet J, Moscinski L, Yun S, Lu CM, Medeiros LJ, Tang G
Hum Pathol 2023 Jun;136:1-15. Epub 2023 Mar 22 doi: 10.1016/j.humpath.2023.03.002. PMID: 36958463
Cross NCP
Clin Lymphoma Myeloma Leuk 2020 Sep;20 Suppl 1:S101-S102. doi: 10.1016/S2152-2650(20)30477-8. PMID: 32862848
Shomali W, Gotlib J
Am J Hematol 2019 Oct;94(10):1149-1167. doi: 10.1002/ajh.25617. PMID: 31423623
Reiter A, Gotlib J
Blood 2017 Feb 9;129(6):704-714. Epub 2016 Dec 27 doi: 10.1182/blood-2016-10-695973. PMID: 28028030
Harrison CJ
Hematology Am Soc Hematol Educ Program 2013;2013:118-25. doi: 10.1182/asheducation-2013.1.118. PMID: 24319172

Clinical prediction guides

Tang G, Tam W, Short NJ, Bose P, Wu D, Hurwitz SN, Bagg A, Rogers HJ, Hsi ED, Quesada AE, Wang W, Miranda RN, Bueso-Ramos CE, Medeiros LJ, Nardi V, Hasserjian RP, Arber DA, Orazi A, Foucar K, Wang SA
Mod Pathol 2021 Sep;34(9):1673-1685. Epub 2021 May 14 doi: 10.1038/s41379-021-00817-7. PMID: 33990705
Lee WY, Pfau RB, Choi SM, Yang J, Xiao H, Putnam EM, Ryan RJ, Bixby DL, Shao L
Cold Spring Harb Mol Case Stud 2020 Apr;6(2) Epub 2020 Apr 1 doi: 10.1101/mcs.a004937. PMID: 32238402Free PMC Article
Reiter A, Gotlib J
Blood 2017 Feb 9;129(6):704-714. Epub 2016 Dec 27 doi: 10.1182/blood-2016-10-695973. PMID: 28028030

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