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Malposition of Heart and Cardiac Apex

MedGen UID:
9872
•Concept ID:
C0024649
•
Congenital Abnormality

Definition

Any anatomical misplacement of the heart and cardiac apex such that the organ occupies an unusual location within the body. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalposition of Heart and Cardiac Apex

Professional guidelines

PubMed

Prenatal diagnosis of fetal unilateral lung agenesis complicated with cardiac malposition.
Zhang Y, Fan M, Ren WD, Xie LM, Ding CW, Sun W, Wang Y, Guo YJ, Cai AL
BMC Pregnancy Childbirth 2013 Mar 26;13:79. doi: 10.1186/1471-2393-13-79. PMID: 23530545Free PMC Article

Recent clinical studies

Etiology

Reducing regional flow stasis and improving intraventricular hemodynamics with a tipless inflow cannula design: An in vitro flow visualization study using the EVAHEART LVAD.
May-Newman K, Montes R, Campos J, Marquez-Maya N, Vu V, Zebrowski E, Motomura T, Benkowski R
Artif Organs 2019 Sep;43(9):834-848. Epub 2019 Jun 9 doi: 10.1111/aor.13477. PMID: 31038753
Surgical Techniques for Implanting the EVAHEART 2 Double Cuff Tipless Inflow Cannula.
Motomura T, Kelly B
ASAIO J 2019 Nov/Dec;65(8):e86-e89. doi: 10.1097/MAT.0000000000000914. PMID: 30394886
Quantitative Assessment of Inflow Malposition in Two Continuous-Flow Left Ventricular Assist Devices.
Sorensen EN, Kon ZN, Feller ED, Pham SM, Griffith BP
Ann Thorac Surg 2018 May;105(5):1377-1383. Epub 2018 Jan 3 doi: 10.1016/j.athoracsur.2017.12.004. PMID: 29305851
Prenatal diagnosis of fetal unilateral lung agenesis complicated with cardiac malposition.
Zhang Y, Fan M, Ren WD, Xie LM, Ding CW, Sun W, Wang Y, Guo YJ, Cai AL
BMC Pregnancy Childbirth 2013 Mar 26;13:79. doi: 10.1186/1471-2393-13-79. PMID: 23530545Free PMC Article
Anatomically corrected malposition of the great arteries: diagnostic difficulties and surgical repair of associated lesions.
Colli AM, de Leval M, Somerville J
Am J Cardiol 1985 May 1;55(11):1367-72. doi: 10.1016/0002-9149(85)90506-5. PMID: 3993572

Diagnosis

Inadvertent defibrillator lead placement into the left ventricle after MitraClip implantation: A case report.
Santarpia G, Passafaro F, Pasceri E, Mongiardo A, Curcio A, Indolfi C
Medicine (Baltimore) 2018 May;97(19):e0733. doi: 10.1097/MD.0000000000010733. PMID: 29742737Free PMC Article
Prenatal Diagnosis of Dextrocardia with Complex Congenital Heart Disease Using Fetal Intelligent Navigation Echocardiography (FINE) and a Literature Review.
Yeo L, Luewan S, Markush D, Gill N, Romero R
Fetal Diagn Ther 2018;43(4):304-316. Epub 2017 Jun 23 doi: 10.1159/000468929. PMID: 28641300Free PMC Article
Prenatal diagnosis of fetal unilateral lung agenesis complicated with cardiac malposition.
Zhang Y, Fan M, Ren WD, Xie LM, Ding CW, Sun W, Wang Y, Guo YJ, Cai AL
BMC Pregnancy Childbirth 2013 Mar 26;13:79. doi: 10.1186/1471-2393-13-79. PMID: 23530545Free PMC Article
Adult presentation of heterotaxic syndromes and related complexes.
Winer-Muram HT
J Thorac Imaging 1995 Winter;10(1):43-57. doi: 10.1097/00005382-199501010-00004. PMID: 7891396
Anatomically corrected malposition of the great arteries: diagnostic difficulties and surgical repair of associated lesions.
Colli AM, de Leval M, Somerville J
Am J Cardiol 1985 May 1;55(11):1367-72. doi: 10.1016/0002-9149(85)90506-5. PMID: 3993572

Therapy

Reducing regional flow stasis and improving intraventricular hemodynamics with a tipless inflow cannula design: An in vitro flow visualization study using the EVAHEART LVAD.
May-Newman K, Montes R, Campos J, Marquez-Maya N, Vu V, Zebrowski E, Motomura T, Benkowski R
Artif Organs 2019 Sep;43(9):834-848. Epub 2019 Jun 9 doi: 10.1111/aor.13477. PMID: 31038753
Surgical Techniques for Implanting the EVAHEART 2 Double Cuff Tipless Inflow Cannula.
Motomura T, Kelly B
ASAIO J 2019 Nov/Dec;65(8):e86-e89. doi: 10.1097/MAT.0000000000000914. PMID: 30394886
Inadvertent Left Ventricle Endocardial or Uncomplicated Right Ventricular Pacing: How to Differentiate in the Emergency Department.
Velibey Y, Yaylak B, Guvenc TS, Cinier G, Kalenderoglu K, Guzelburc O, Yildirimturk O
J Emerg Med 2018 May;54(5):e91-e95. Epub 2018 Mar 6 doi: 10.1016/j.jemermed.2018.01.034. PMID: 29523425
Double left ventricular pacing following accidental malpositioning of the right ventricular electrode during implantation of a cardiac resynchronization therapy device.
Dissmann R, Wolthoff U, Zabel M
J Cardiothorac Surg 2013 Jun 27;8:162. doi: 10.1186/1749-8090-8-162. PMID: 23806123Free PMC Article
Malpositioning of a pacemaker lead to the left ventricle accompanied by posterior mitral leaflet injury.
Seki H, Fukui T, Shimokawa T, Manabe S, Watanabe Y, Chino K, Takanashi S
Interact Cardiovasc Thorac Surg 2009 Feb;8(2):235-7. Epub 2008 Nov 27 doi: 10.1510/icvts.2008.190793. PMID: 19038982

Prognosis

Crossed pulmonary arteries associated with single atrium in an adult: a case report.
Fu F, Yang J, Zhang J, Feng Y
BMC Cardiovasc Disord 2016 Sep 5;16(1):172. doi: 10.1186/s12872-016-0354-8. PMID: 27596357Free PMC Article
Clinics in diagnostic imaging (160). Levocardia with abdominal situs inversus.
Abdullah NL, Quek SC, Seto KY, Teo LL
Singapore Med J 2015 Apr;56(4):198-201; quiz 202. doi: 10.11622/smedj.2015059. PMID: 25917470Free PMC Article
Adult presentation of heterotaxic syndromes and related complexes.
Winer-Muram HT
J Thorac Imaging 1995 Winter;10(1):43-57. doi: 10.1097/00005382-199501010-00004. PMID: 7891396
Anatomically corrected malposition of the great arteries: diagnostic difficulties and surgical repair of associated lesions.
Colli AM, de Leval M, Somerville J
Am J Cardiol 1985 May 1;55(11):1367-72. doi: 10.1016/0002-9149(85)90506-5. PMID: 3993572
An approach to cardiac malposition and the heterotaxy syndrome using 99mTc sulfur colloid imaging.
Fitzer PM
AJR Am J Roentgenol 1976 Dec;127(6):1021-5. doi: 10.2214/ajr.127.6.1021. PMID: 998814

Clinical prediction guides

Reducing regional flow stasis and improving intraventricular hemodynamics with a tipless inflow cannula design: An in vitro flow visualization study using the EVAHEART LVAD.
May-Newman K, Montes R, Campos J, Marquez-Maya N, Vu V, Zebrowski E, Motomura T, Benkowski R
Artif Organs 2019 Sep;43(9):834-848. Epub 2019 Jun 9 doi: 10.1111/aor.13477. PMID: 31038753
Inadvertent defibrillator lead placement into the left ventricle after MitraClip implantation: A case report.
Santarpia G, Passafaro F, Pasceri E, Mongiardo A, Curcio A, Indolfi C
Medicine (Baltimore) 2018 May;97(19):e0733. doi: 10.1097/MD.0000000000010733. PMID: 29742737Free PMC Article
An approach to cardiac malposition and the heterotaxy syndrome using 99mTc sulfur colloid imaging.
Fitzer PM
AJR Am J Roentgenol 1976 Dec;127(6):1021-5. doi: 10.2214/ajr.127.6.1021. PMID: 998814

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