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Metastatic Malignant Neoplasm in the Small Intestine

MedGen UID:
99212
Concept ID:
C0494164
Neoplastic Process
Synonyms: Cancer metastatic to small intestine; Metastases to Small Intestine; Metastasis to small intestine; Metastasis to the Small Bowel; Metastasis to the Small Intestine; Metastatic malignant neoplasm of small intestine; Metastatic malignant neoplasm to small intestine; Metastatic Malignant Neoplasm to the Small Intestine; Metastatic Neoplasm to the Small Intestine; Secondary malignant neoplasm of small intestine; Secondary Malignant Neoplasm to the Small Bowel; Secondary Malignant Neoplasm to the Small Intestine; Secondary Malignant Tumor to the Small Bowel; Secondary Malignant Tumor to the Small Intestine
SNOMED CT: Metastasis to small intestine (94580002); Secondary malignant neoplasm of small intestine (94580002); Metastatic malignant neoplasm to small intestine (94580002); Cancer metastatic to small intestine (94580002); Metastatic malignant neoplasm of small intestine (94580002)

Definition

A malignant neoplasm that has spread to the small intestine from another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Small Intestine

Professional guidelines

PubMed

Chiorean EG, Chiaro MD, Tempero MA, Malafa MP, Benson AB, Cardin DB, Christensen JA, Chung V, Czito B, Dillhoff M, Donahue TR, Dotan E, Fountzilas C, Glazer ES, Hardacre J, Hawkins WG, Klute K, Ko AH, Kunstman JW, LoConte N, Lowy AM, Masood A, Moravek C, Nakakura EK, Narang AK, Nardo L, Obando J, Polanco PM, Reddy S, Reyngold M, Scaife C, Shen J, Truty MJ, Vollmer C, Wolff RA, Wolpin BM, Rn BM, Lubin S, Darlow SD
J Natl Compr Canc Netw 2023 Jul;21(7):753-782. doi: 10.6004/jnccn.2023.0034. PMID: 37433437
Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen YJ, Ciombor KK, Cohen SA, Cooper HS, Deming DA, Garrido-Laguna I, Grem JL, Hoffe SE, Hubbard J, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Nurkin S, Overman MJ, Parikh A, Patel H, Pedersen KS, Saltz LB, Schneider C, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Johnson-Chilla A, Gregory KM, Gurski LA
J Natl Compr Canc Netw 2019 Sep 1;17(9):1109-1133. doi: 10.6004/jnccn.2019.0043. PMID: 31487687Free PMC Article
Miettinen M, Lasota J
Arch Pathol Lab Med 2006 Oct;130(10):1466-78. doi: 10.5858/2006-130-1466-GSTROM. PMID: 17090188

Recent clinical studies

Etiology

Wu Z, Wang W, Zhang K, Fan M, Lin R
Int J Surg 2023 Jun 1;109(6):1629-1638. doi: 10.1097/JS9.0000000000000336. PMID: 37133986Free PMC Article
Ocvirk S, O'Keefe SJD
Semin Cancer Biol 2021 Aug;73:347-355. Epub 2020 Oct 16 doi: 10.1016/j.semcancer.2020.10.003. PMID: 33069873
Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen YJ, Ciombor KK, Cohen SA, Cooper HS, Deming DA, Garrido-Laguna I, Grem JL, Hoffe SE, Hubbard J, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Nurkin S, Overman MJ, Parikh A, Patel H, Pedersen KS, Saltz LB, Schneider C, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Johnson-Chilla A, Gregory KM, Gurski LA
J Natl Compr Canc Netw 2019 Sep 1;17(9):1109-1133. doi: 10.6004/jnccn.2019.0043. PMID: 31487687Free PMC Article
Aparicio T, Zaanan A, Mary F, Afchain P, Manfredi S, Evans TR
Gastroenterol Clin North Am 2016 Sep;45(3):447-57. doi: 10.1016/j.gtc.2016.04.004. PMID: 27546842
Ahn DH, Bekaii-Saab T
Am Soc Clin Oncol Educ Book 2014:112-5. doi: 10.14694/EdBook_AM.2014.34.112. PMID: 24857067Free PMC Article

Diagnosis

Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen YJ, Ciombor KK, Cohen SA, Cooper HS, Deming DA, Garrido-Laguna I, Grem JL, Hoffe SE, Hubbard J, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Nurkin S, Overman MJ, Parikh A, Patel H, Pedersen KS, Saltz LB, Schneider C, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Johnson-Chilla A, Gregory KM, Gurski LA
J Natl Compr Canc Netw 2019 Sep 1;17(9):1109-1133. doi: 10.6004/jnccn.2019.0043. PMID: 31487687Free PMC Article
Kumar P, Malla S, Singh A, Razik A, Madhusudhan KS
Abdom Radiol (NY) 2019 Aug;44(8):2708-2720. Epub 2019 May 11 doi: 10.1007/s00261-019-02053-9. PMID: 31079195
Aparicio T, Zaanan A, Mary F, Afchain P, Manfredi S, Evans TR
Gastroenterol Clin North Am 2016 Sep;45(3):447-57. doi: 10.1016/j.gtc.2016.04.004. PMID: 27546842
Zouhairi ME, Venner A, Charabaty A, Pishvaian MJ
Curr Treat Options Oncol 2008 Dec;9(4-6):388-99. Epub 2009 Apr 14 doi: 10.1007/s11864-009-0098-0. PMID: 19365735
Miettinen M, Lasota J
Arch Pathol Lab Med 2006 Oct;130(10):1466-78. doi: 10.5858/2006-130-1466-GSTROM. PMID: 17090188

Therapy

Ocvirk S, O'Keefe SJD
Semin Cancer Biol 2021 Aug;73:347-355. Epub 2020 Oct 16 doi: 10.1016/j.semcancer.2020.10.003. PMID: 33069873
Massironi S, Cavalcoli F, Rausa E, Invernizzi P, Braga M, Vecchi M
Dig Liver Dis 2020 Mar;52(3):253-261. Epub 2019 Dec 28 doi: 10.1016/j.dld.2019.11.013. PMID: 31892505
Aparicio T, Zaanan A, Mary F, Afchain P, Manfredi S, Evans TR
Gastroenterol Clin North Am 2016 Sep;45(3):447-57. doi: 10.1016/j.gtc.2016.04.004. PMID: 27546842
Ahn DH, Bekaii-Saab T
Am Soc Clin Oncol Educ Book 2014:112-5. doi: 10.14694/EdBook_AM.2014.34.112. PMID: 24857067Free PMC Article
Joensuu H, Hohenberger P, Corless CL
Lancet 2013 Sep 14;382(9896):973-83. Epub 2013 Apr 24 doi: 10.1016/S0140-6736(13)60106-3. PMID: 23623056

Prognosis

Horn SR, Stoltzfus KC, Lehrer EJ, Dawson LA, Tchelebi L, Gusani NJ, Sharma NK, Chen H, Trifiletti DM, Zaorsky NG
Cancer Epidemiol 2020 Aug;67:101760. Epub 2020 Jun 17 doi: 10.1016/j.canep.2020.101760. PMID: 32562887
Scott AT, Howe JR
J Oncol Pract 2018 Aug;14(8):471-482. doi: 10.1200/JOP.18.00135. PMID: 30096273Free PMC Article
Aparicio T, Zaanan A, Mary F, Afchain P, Manfredi S, Evans TR
Gastroenterol Clin North Am 2016 Sep;45(3):447-57. doi: 10.1016/j.gtc.2016.04.004. PMID: 27546842
Zouhairi ME, Venner A, Charabaty A, Pishvaian MJ
Curr Treat Options Oncol 2008 Dec;9(4-6):388-99. Epub 2009 Apr 14 doi: 10.1007/s11864-009-0098-0. PMID: 19365735
Miettinen M, Lasota J
Arch Pathol Lab Med 2006 Oct;130(10):1466-78. doi: 10.5858/2006-130-1466-GSTROM. PMID: 17090188

Clinical prediction guides

Matsubara J, Mukai K, Kondo T, Yoshioka M, Kage H, Oda K, Kudo R, Ikeda S, Ebi H, Muro K, Hayashi R, Tokudome N, Yamamoto N, Muto M
JAMA Netw Open 2023 Jul 3;6(7):e2323336. doi: 10.1001/jamanetworkopen.2023.23336. PMID: 37459099Free PMC Article
Wu Z, Wang W, Zhang K, Fan M, Lin R
Int J Surg 2023 Jun 1;109(6):1629-1638. doi: 10.1097/JS9.0000000000000336. PMID: 37133986Free PMC Article
Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003
Neoptolemos JP, Moore MJ, Cox TF, Valle JW, Palmer DH, McDonald AC, Carter R, Tebbutt NC, Dervenis C, Smith D, Glimelius B, Charnley RM, Lacaine F, Scarfe AG, Middleton MR, Anthoney A, Ghaneh P, Halloran CM, Lerch MM, Oláh A, Rawcliffe CL, Verbeke CS, Campbell F, Büchler MW; European Study Group for Pancreatic Cancer
JAMA 2012 Jul 11;308(2):147-56. doi: 10.1001/jama.2012.7352. PMID: 22782416
Miettinen M, Lasota J
Arch Pathol Lab Med 2006 Oct;130(10):1466-78. doi: 10.5858/2006-130-1466-GSTROM. PMID: 17090188

Recent systematic reviews

Zhang Y, Ding H, Zhang Y, Tian J, Yang L, Dong Z, Wang J, Wang Y, Zhang Y, Wang Z
Urol Int 2023;107(1):1-14. Epub 2022 Jul 14 doi: 10.1159/000525017. PMID: 35835038
Baelum JK, Qvist N, Ellebaek MB
Colorectal Dis 2021 Oct;23(10):2501-2514. Epub 2021 Aug 10 doi: 10.1111/codi.15839. PMID: 34309170
Banting SP, Waters PS, Peacock O, Narasimhan V, Lynch AC, McCormick JJ, Warrier SK, Heriot AG
ANZ J Surg 2021 Mar;91(3):282-290. Epub 2020 Aug 31 doi: 10.1111/ans.16188. PMID: 32869479
Almond LM, Hodson J, Ford SJ, Gourevitch D, Roberts KJ, Shah T, Isaac J, Desai A
Eur J Surg Oncol 2017 Oct;43(10):1808-1815. Epub 2017 May 25 doi: 10.1016/j.ejso.2017.05.016. PMID: 28583792
Luchini C, Veronese N, Pea A, Sergi G, Manzato E, Nottegar A, Solmi M, Capelli P, Scarpa A
Eur J Gastroenterol Hepatol 2016 Feb;28(2):205-9. doi: 10.1097/MEG.0000000000000520. PMID: 26566063

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