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Benign Retroperitoneal Neoplasm

MedGen UID:: 99223
•Concept ID:: C0496873
•: Neoplastic Process

Synonyms:	Benign neoplasm of retroperitoneum; Benign neoplasm of the retroperitoneum; Benign retroperitoneal tumor
SNOMED CT:	Benign neoplasm of retroperitoneum (92433007); Benign retroperitoneal tumor (92433007); Benign neoplasm of the retroperitoneum (92433007)

Definition

A neoplasm that arises from the retroperitoneum and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBenign Retroperitoneal Neoplasm

Pathological process
- Disease
  - Neoplasm
    - Neoplasm by Special Category
      - Benign neoplasm
        Benign Peritoneal and Retroperitoneal Neoplasm
        Benign Retroperitoneal Neoplasm
        Benign neoplasm of adrenal gland
        Benign Adrenal Cortical Neoplasm
        Adrenal Cortical Adenomatoid Tumor
        Adrenocortical adenoma
        Benign neoplasm of adrenal medulla
        Adrenal Gland Ganglioneuroma
        Adrenal Gland Schwannoma
        Benign adrenal gland pheochromocytoma
        Retroperitoneal Ganglioneuroma

Professional guidelines

PubMed

Current management of benign retroperitoneal tumors.

Tirotta F, Napolitano A, Noh S, Schmitz E, Nessim C, Patel D, Sicklick JK, Smith M, Thway K, van der Hage J, Ford SJ, Tseng WW
Eur J Surg Oncol 2023 Jun;49(6):1081-1090. Epub 2022 Jul 19 doi: 10.1016/j.ejso.2022.07.006. PMID: 35879135

Overview of primary adult retroperitoneal tumours.

Improta L, Tzanis D, Bouhadiba T, Abdelhafidh K, Bonvalot S
Eur J Surg Oncol 2020 Sep;46(9):1573-1579. Epub 2020 May 21 doi: 10.1016/j.ejso.2020.04.054. PMID: 32600897

Risk Factors and Treatment Outcomes of 1,375 Patients with Testicular Leydig Cell Tumors: Analysis of Published Case Series Data.

Fankhauser CD, Grogg JB, Hayoz S, Wettstein MS, Dieckmann KP, Sulser T, Bode PK, Clarke NW, Beyer J, Hermanns T
J Urol 2020 May;203(5):949-956. Epub 2019 Dec 17 doi: 10.1097/JU.0000000000000705. PMID: 31845841

See all (45)

Recent clinical studies

Etiology

Current management of benign retroperitoneal tumors.

American Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary.

Yip L, Duh QY, Wachtel H, Jimenez C, Sturgeon C, Lee C, Velázquez-Fernández D, Berber E, Hammer GD, Bancos I, Lee JA, Marko J, Morris-Wiseman LF, Hughes MS, Livhits MJ, Han MA, Smith PW, Wilhelm S, Asa SL, Fahey TJ 3rd, McKenzie TJ, Strong VE, Perrier ND
JAMA Surg 2022 Oct 1;157(10):870-877. doi: 10.1001/jamasurg.2022.3544. PMID: 35976622 Free PMC Article

Risk Factors and Treatment Outcomes of 1,375 Patients with Testicular Leydig Cell Tumors: Analysis of Published Case Series Data.

Retroperitoneal laparoscopic adrenalectomy.

Munver R, Ilbeigi P
Curr Urol Rep 2005 Feb;6(1):72-7. doi: 10.1007/s11934-005-0070-x. PMID: 15610700

Lipoblastoma.

Chun YS, Kim WK, Park KW, Lee SC, Jung SE
J Pediatr Surg 2001 Jun;36(6):905-7. doi: 10.1053/jpsu.2001.23969. PMID: 11381423

See all (363)

Diagnosis

Review of diagnosis, differential diagnosis, and management of retroperitoneal lymphangioma.

Hoang VT, Nguyen MD, Van HAT, Hoang DT
Jpn J Radiol 2023 Mar;41(3):283-301. Epub 2022 Nov 3 doi: 10.1007/s11604-022-01356-0. PMID: 36327088

Current management of benign retroperitoneal tumors.

Retroperitoneal tumors: Review of diagnosis and management.

Sassa N
Int J Urol 2020 Dec;27(12):1058-1070. Epub 2020 Sep 10 doi: 10.1111/iju.14361. PMID: 32914475

Overview of primary adult retroperitoneal tumours.

Improta L, Tzanis D, Bouhadiba T, Abdelhafidh K, Bonvalot S
Eur J Surg Oncol 2020 Sep;46(9):1573-1579. Epub 2020 May 21 doi: 10.1016/j.ejso.2020.04.054. PMID: 32600897

Retroperitoneal schwannoma.

Goh BK, Tan YM, Chung YF, Chow PK, Ooi LL, Wong WK
Am J Surg 2006 Jul;192(1):14-8. doi: 10.1016/j.amjsurg.2005.12.010. PMID: 16769268

See all (821)

Therapy

Preoperative contrast-enhanced CT-based radiomics nomogram for differentiating benign and malignant primary retroperitoneal tumors.

Xu J, Guo J, Yang HQ, Ji QL, Song RJ, Hou F, Liang HY, Liu SL, Tian LT, Wang HX
Eur Radiol 2023 Oct;33(10):6781-6793. Epub 2023 May 6 doi: 10.1007/s00330-023-09686-x. PMID: 37148350

Diagnostic yield and safety of percutaneous CT-guided biopsy of retroperitoneal lesions and analysis of imaging features.

Singh AK, Neyaz Z, Verma R, Gupta A, Mishra R, Mishra P
Acta Radiol 2022 Feb;63(2):149-158. Epub 2021 Feb 2 doi: 10.1177/0284185121990286. PMID: 33530697

Adrenal tumours: open surgery versus minimally invasive surgery.

Fiori C, Checcucci E, Amparore D, Cattaneo G, Manfredi M, Porpiglia F
Curr Opin Oncol 2020 Jan;32(1):27-34. doi: 10.1097/CCO.0000000000000594. PMID: 31644473

Robotic distal pancreatectomy: a valid option?

Jung MK, Buchs NC, Azagury DE, Hagen ME, Morel P
Minerva Chir 2013 Oct;68(5):489-97. PMID: 24101006

Autoimmune pancreatitis: current concepts.

Wang Q, Zhang X, Zhang F
Sci China Life Sci 2013 Mar;56(3):246-53. Epub 2013 Mar 23 doi: 10.1007/s11427-013-4450-z. PMID: 23526391

See all (111)

Prognosis

Preoperative contrast-enhanced CT-based radiomics nomogram for differentiating benign and malignant primary retroperitoneal tumors.

Xu J, Guo J, Yang HQ, Ji QL, Song RJ, Hou F, Liang HY, Liu SL, Tian LT, Wang HX
Eur Radiol 2023 Oct;33(10):6781-6793. Epub 2023 May 6 doi: 10.1007/s00330-023-09686-x. PMID: 37148350

Updates in Pathology for Retroperitoneal Soft Tissue Sarcoma.

Mack T, Purgina B
Curr Oncol 2022 Sep 7;29(9):6400-6418. doi: 10.3390/curroncol29090504. PMID: 36135073 Free PMC Article

Risk Factors and Treatment Outcomes of 1,375 Patients with Testicular Leydig Cell Tumors: Analysis of Published Case Series Data.

Retrorectal tumors.

Bullard Dunn K
Surg Clin North Am 2010 Feb;90(1):163-71, Table of Contents. doi: 10.1016/j.suc.2009.09.009. PMID: 20109640

Retroperitoneal laparoscopic adrenalectomy.

Munver R, Ilbeigi P
Curr Urol Rep 2005 Feb;6(1):72-7. doi: 10.1007/s11934-005-0070-x. PMID: 15610700

See all (356)

Clinical prediction guides

Preoperative contrast-enhanced CT-based radiomics nomogram for differentiating benign and malignant primary retroperitoneal tumors.

Xu J, Guo J, Yang HQ, Ji QL, Song RJ, Hou F, Liang HY, Liu SL, Tian LT, Wang HX
Eur Radiol 2023 Oct;33(10):6781-6793. Epub 2023 May 6 doi: 10.1007/s00330-023-09686-x. PMID: 37148350

Risk Factors and Treatment Outcomes of 1,375 Patients with Testicular Leydig Cell Tumors: Analysis of Published Case Series Data.

An update on recent developments in rupture of renal angiomyolipoma.

Wang C, Li X, Peng L, Gou X, Fan J
Medicine (Baltimore) 2018 Apr;97(16):e0497. doi: 10.1097/MD.0000000000010497. PMID: 29668633 Free PMC Article

Retroperitoneal tumours: review of management.

Strauss DC, Hayes AJ, Thomas JM
Ann R Coll Surg Engl 2011 May;93(4):275-80. doi: 10.1308/003588411X571944. PMID: 21944791 Free PMC Article

Primary retroperitoneal tumors.

Oriana S, Bonardi P, Preda F
Tumori 1977 Jul-Aug;63(4):397-405. doi: 10.1177/030089167706300412. PMID: 929704

See all (174)

Recent systematic reviews

Robotic Nerve Sheath Tumor Resection With Intraoperative Neuromonitoring: Case Series and Systematic Review.

Curry BP, Alvarez R, Widemann BC, Johnson M, Agarwal PK, Lehky T, Valera V, Chittiboina P
Oper Neurosurg (Hagerstown) 2022 Feb 1;22(2):44-50. doi: 10.1227/ONS.0000000000000051. PMID: 35007270 Free PMC Article

Total resection of a giant retroperitoneal and mediastinal ganglioneuroma-case report and systematic review of the literature.

Kirchweger P, Wundsam HV, Fischer I, Rösch CS, Böhm G, Tsybrovskyy O, Alibegovic V, Függer R
World J Surg Oncol 2020 Sep 18;18(1):248. doi: 10.1186/s12957-020-02016-1. PMID: 32948207 Free PMC Article

International Consultation on Urological Diseases and European Association of Urology International Consultation on Minimally Invasive Surgery in Urology: laparoscopic and robotic adrenalectomy.

Ball MW, Hemal AK, Allaf ME
BJU Int 2017 Jan;119(1):13-21. Epub 2016 Aug 19 doi: 10.1111/bju.13592. PMID: 27431446

Intraoperative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses.

Ratnavelu ND, Brown AP, Mallett S, Scholten RJ, Patel A, Founta C, Galaal K, Cross P, Naik R
Cochrane Database Syst Rev 2016 Mar 1;3(3):CD010360. doi: 10.1002/14651858.CD010360.pub2. PMID: 26930463 Free PMC Article

Management approach and surgical strategies for retrorectal tumours: a systematic review.

Toh JW, Morgan M
Colorectal Dis 2016 Apr;18(4):337-50. doi: 10.1111/codi.13232. PMID: 26663419

See all (7)

MedGen

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Benign Retroperitoneal Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Recent activity