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Nervous system benign neoplasm

MedGen UID:
99232
Concept ID:
C0497550
Neoplastic Process
Synonyms: Benign neoplasm of nervous system; Benign Neoplasm of Nervous System; benign neoplasm of nervous system; Benign Neoplasm of the Nervous System; benign neoplasm of the nervous system; Benign Nervous System Neoplasm; benign nervous system neoplasm; Benign Nervous System Tumor; benign nervous system tumor; benign nervous system tumour; Benign tumor of nervous system; Benign Tumor of Nervous System; benign tumor of nervous system; Benign Tumor of the Nervous System; benign tumor of the nervous system; benign tumour of nervous system; benign tumour of the nervous system; nervous system benign neoplasm; Nervous System Neoplasm, Benign; nervous system neoplasm, benign
SNOMED CT: Benign tumor of nervous system (92247009); Benign neoplasm of nervous system (92247009)
 
Monarch Initiative: MONDO:0000648

Definition

A neoplasm that arises from the nervous system and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNervous system benign neoplasm

Professional guidelines

PubMed

Graus F, Vogrig A, Muñiz-Castrillo S, Antoine JG, Desestret V, Dubey D, Giometto B, Irani SR, Joubert B, Leypoldt F, McKeon A, Prüss H, Psimaras D, Thomas L, Titulaer MJ, Vedeler CA, Verschuuren JJ, Dalmau J, Honnorat J
Neurol Neuroimmunol Neuroinflamm 2021 Jul;8(4) Epub 2021 May 18 doi: 10.1212/NXI.0000000000001014. PMID: 34006622Free PMC Article
Weller M, van den Bent M, Preusser M, Le Rhun E, Tonn JC, Minniti G, Bendszus M, Balana C, Chinot O, Dirven L, French P, Hegi ME, Jakola AS, Platten M, Roth P, Rudà R, Short S, Smits M, Taphoorn MJB, von Deimling A, Westphal M, Soffietti R, Reifenberger G, Wick W
Nat Rev Clin Oncol 2021 Mar;18(3):170-186. Epub 2020 Dec 8 doi: 10.1038/s41571-020-00447-z. PMID: 33293629Free PMC Article
Greenlee H, DuPont-Reyes MJ, Balneaves LG, Carlson LE, Cohen MR, Deng G, Johnson JA, Mumber M, Seely D, Zick SM, Boyce LM, Tripathy D
CA Cancer J Clin 2017 May 6;67(3):194-232. Epub 2017 Apr 24 doi: 10.3322/caac.21397. PMID: 28436999Free PMC Article

Recent clinical studies

Etiology

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Kopmar NE, Cassaday RD
Blood 2023 Mar 23;141(12):1379-1388. doi: 10.1182/blood.2022017035. PMID: 36548957Free PMC Article
Paul S, Short NJ
Curr Oncol Rep 2022 Apr;24(4):427-436. Epub 2022 Feb 10 doi: 10.1007/s11912-022-01220-4. PMID: 35141858
Gritsch S, Batchelor TT, Gonzalez Castro LN
Cancer 2022 Jan 1;128(1):47-58. Epub 2021 Oct 11 doi: 10.1002/cncr.33918. PMID: 34633681
McFaline-Figueroa JR, Lee EQ
Am J Med 2018 Aug;131(8):874-882. Epub 2018 Jan 31 doi: 10.1016/j.amjmed.2017.12.039. PMID: 29371158

Diagnosis

Nieblas-Bedolla E, Zuccato J, Kluger H, Zadeh G, Brastianos PK
Hematol Oncol Clin North Am 2022 Feb;36(1):161-188. Epub 2021 Oct 25 doi: 10.1016/j.hoc.2021.08.004. PMID: 34711458
Claus M, Van Der Linden M, Van Dorpe J, Lapauw B, T'Sjoen G
Pituitary 2021 Dec;24(6):970-977. Epub 2021 Sep 13 doi: 10.1007/s11102-021-01186-9. PMID: 34518998
Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW
Neuro Oncol 2021 Aug 2;23(8):1231-1251. doi: 10.1093/neuonc/noab106. PMID: 34185076Free PMC Article
Wang K, Zhao XH, Liu J, Zhang R, Li JP
Biochim Biophys Acta Rev Cancer 2020 Jan;1873(1):188313. Epub 2019 Oct 21 doi: 10.1016/j.bbcan.2019.188313. PMID: 31647986
Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW
Acta Neuropathol 2016 Jun;131(6):803-20. Epub 2016 May 9 doi: 10.1007/s00401-016-1545-1. PMID: 27157931

Therapy

Shi DD, Guo JA, Hoffman HI, Su J, Mino-Kenudson M, Barth JL, Schenkel JM, Loeffler JS, Shih HA, Hong TS, Wo JY, Aguirre AJ, Jacks T, Zheng L, Wen PY, Wang TC, Hwang WL
Lancet Oncol 2022 Feb;23(2):e62-e74. doi: 10.1016/S1470-2045(21)00596-9. PMID: 35114133Free PMC Article
Sampson JH, Gunn MD, Fecci PE, Ashley DM
Nat Rev Cancer 2020 Jan;20(1):12-25. Epub 2019 Dec 5 doi: 10.1038/s41568-019-0224-7. PMID: 31806885Free PMC Article
Wen PY, Chang SM, Van den Bent MJ, Vogelbaum MA, Macdonald DR, Lee EQ
J Clin Oncol 2017 Jul 20;35(21):2439-2449. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.72.7511. PMID: 28640707Free PMC Article
Grommes C, DeAngelis LM
J Clin Oncol 2017 Jul 20;35(21):2410-2418. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.72.7602. PMID: 28640701Free PMC Article
Lin NU, Lee EQ, Aoyama H, Barani IJ, Barboriak DP, Baumert BG, Bendszus M, Brown PD, Camidge DR, Chang SM, Dancey J, de Vries EG, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wen PY; Response Assessment in Neuro-Oncology (RANO) group
Lancet Oncol 2015 Jun;16(6):e270-8. Epub 2015 May 27 doi: 10.1016/S1470-2045(15)70057-4. PMID: 26065612

Prognosis

Ostrom QT, Francis SS, Barnholtz-Sloan JS
Curr Neurol Neurosci Rep 2021 Nov 24;21(12):68. doi: 10.1007/s11910-021-01152-9. PMID: 34817716Free PMC Article
Anyanwu CT, Robinson TM, Huang JH
Clin Transl Oncol 2020 May;22(5):623-630. Epub 2019 Jul 16 doi: 10.1007/s12094-019-02179-8. PMID: 31313067
Ostrom QT, Cioffi G, Gittleman H, Patil N, Waite K, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol 2019 Nov 1;21(Suppl 5):v1-v100. doi: 10.1093/neuonc/noz150. PMID: 31675094Free PMC Article
Ostrom QT, Gittleman H, Truitt G, Boscia A, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol 2018 Oct 1;20(suppl_4):iv1-iv86. doi: 10.1093/neuonc/noy131. PMID: 30445539Free PMC Article
Custódio-Santos T, Videira M, Brito MA
Biochim Biophys Acta Rev Cancer 2017 Aug;1868(1):132-147. Epub 2017 Mar 21 doi: 10.1016/j.bbcan.2017.03.004. PMID: 28341420

Clinical prediction guides

Grommes C
Continuum (Minneap Minn) 2020 Dec;26(6):1476-1494. doi: 10.1212/CON.0000000000000936. PMID: 33273169
Zichová A, Eckschlager T, Ganevová M, Malinová B, Lukš A, Kruseová J
Cancer Epidemiol 2020 Oct;68:101779. Epub 2020 Jul 15 doi: 10.1016/j.canep.2020.101779. PMID: 32682319
Erker C, Tamrazi B, Poussaint TY, Mueller S, Mata-Mbemba D, Franceschi E, Brandes AA, Rao A, Haworth KB, Wen PY, Goldman S, Vezina G, MacDonald TJ, Dunkel IJ, Morgan PS, Jaspan T, Prados MD, Warren KE
Lancet Oncol 2020 Jun;21(6):e317-e329. doi: 10.1016/S1470-2045(20)30173-X. PMID: 32502458
Xu Z, Shioda S, Masahisa J, Kawakami Y, Ohtaki H, Lim HC, Wang S, Zhao X, Liu Y, Zhou D, Guo Y
Curr Pharm Des 2017;23(11):1687-1692. doi: 10.2174/1381612822666161025152942. PMID: 27784236
Sarkar D, Fisher PB
Adv Cancer Res 2013;120:39-74. doi: 10.1016/B978-0-12-401676-7.00002-4. PMID: 23889987Free PMC Article

Recent systematic reviews

Larsson SC, Burgess S
EBioMedicine 2022 Aug;82:104154. Epub 2022 Jul 8 doi: 10.1016/j.ebiom.2022.104154. PMID: 35816897Free PMC Article
Gondi V, Bauman G, Bradfield L, Burri SH, Cabrera AR, Cunningham DA, Eaton BR, Hattangadi-Gluth JA, Kim MM, Kotecha R, Kraemer L, Li J, Nagpal S, Rusthoven CG, Suh JH, Tomé WA, Wang TJC, Zimmer AS, Ziu M, Brown PD
Pract Radiat Oncol 2022 Jul-Aug;12(4):265-282. Epub 2022 May 6 doi: 10.1016/j.prro.2022.02.003. PMID: 35534352
Greenlee H, DuPont-Reyes MJ, Balneaves LG, Carlson LE, Cohen MR, Deng G, Johnson JA, Mumber M, Seely D, Zick SM, Boyce LM, Tripathy D
CA Cancer J Clin 2017 May 6;67(3):194-232. Epub 2017 Apr 24 doi: 10.3322/caac.21397. PMID: 28436999Free PMC Article
de Menezes RF, Bergmann A, Thuler LC
Asian Pac J Cancer Prev 2013;14(9):4965-72. doi: 10.7314/apjcp.2013.14.9.4965. PMID: 24175760
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893

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