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Postoperative nausea and vomiting

MedGen UID:
99257
Concept ID:
C0520909
Sign or Symptom
Synonyms: Nausea and Vomiting, Postoperative; PONV; Postoperative Nausea and Vomiting
SNOMED CT: PONV - Postoperative nausea and vomiting (1488000); Postoperative nausea and vomiting (1488000)

Definition

Emesis and queasiness occurring after anesthesia. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPostoperative nausea and vomiting

Professional guidelines

PubMed

Elvir-Lazo OL, White PF, Yumul R, Cruz Eng H
F1000Res 2020;9 Epub 2020 Aug 13 doi: 10.12688/f1000research.21832.1. PMID: 32913634Free PMC Article
Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, Jin Z, Kovac AL, Meyer TA, Urman RD, Apfel CC, Ayad S, Beagley L, Candiotti K, Englesakis M, Hedrick TL, Kranke P, Lee S, Lipman D, Minkowitz HS, Morton J, Philip BK
Anesth Analg 2020 Aug;131(2):411-448. doi: 10.1213/ANE.0000000000004833. PMID: 32467512
Hines S, Steels E, Chang A, Gibbons K
Cochrane Database Syst Rev 2018 Mar 10;3(3):CD007598. doi: 10.1002/14651858.CD007598.pub3. PMID: 29523018Free PMC Article

Recent clinical studies

Etiology

Rajan N, Joshi GP
Curr Opin Anaesthesiol 2021 Dec 1;34(6):695-702. doi: 10.1097/ACO.0000000000001063. PMID: 34560688
Kovac AL
Paediatr Drugs 2021 Jan;23(1):11-37. Epub 2020 Oct 27 doi: 10.1007/s40272-020-00424-0. PMID: 33108649
Veiga-Gil L, Pueyo J, López-Olaondo L
Rev Esp Anestesiol Reanim 2017 Apr;64(4):223-232. Epub 2016 Dec 29 doi: 10.1016/j.redar.2016.10.001. PMID: 28041609
Horn CC, Wallisch WJ, Homanics GE, Williams JP
Eur J Pharmacol 2014 Jan 5;722:55-66. Epub 2013 Oct 26 doi: 10.1016/j.ejphar.2013.10.037. PMID: 24495419Free PMC Article
Gan TJ, Diemunsch P, Habib AS, Kovac A, Kranke P, Meyer TA, Watcha M, Chung F, Angus S, Apfel CC, Bergese SD, Candiotti KA, Chan MT, Davis PJ, Hooper VD, Lagoo-Deenadayalan S, Myles P, Nezat G, Philip BK, Tramèr MR; Society for Ambulatory Anesthesia
Anesth Analg 2014 Jan;118(1):85-113. doi: 10.1213/ANE.0000000000000002. PMID: 24356162

Diagnosis

Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, Jin Z, Kovac AL, Meyer TA, Urman RD, Apfel CC, Ayad S, Beagley L, Candiotti K, Englesakis M, Hedrick TL, Kranke P, Lee S, Lipman D, Minkowitz HS, Morton J, Philip BK
Anesth Analg 2020 Aug;131(2):411-448. doi: 10.1213/ANE.0000000000004833. PMID: 32467512
Hashimoto H, Abe M, Tokuyama O, Mizutani H, Uchitomi Y, Yamaguchi T, Hoshina Y, Sakata Y, Takahashi TY, Nakashima K, Nakao M, Takei D, Zenda S, Mizukami K, Iwasa S, Sakurai M, Yamamoto N, Ohe Y
Lancet Oncol 2020 Feb;21(2):242-249. Epub 2019 Dec 11 doi: 10.1016/S1470-2045(19)30678-3. PMID: 31838011
Brinck EC, Tiippana E, Heesen M, Bell RF, Straube S, Moore RA, Kontinen V
Cochrane Database Syst Rev 2018 Dec 20;12(12):CD012033. doi: 10.1002/14651858.CD012033.pub4. PMID: 30570761Free PMC Article
Miller D, Lewis SR, Pritchard MW, Schofield-Robinson OJ, Shelton CL, Alderson P, Smith AF
Cochrane Database Syst Rev 2018 Aug 21;8(8):CD012317. doi: 10.1002/14651858.CD012317.pub2. PMID: 30129968Free PMC Article
Gan TJ, Diemunsch P, Habib AS, Kovac A, Kranke P, Meyer TA, Watcha M, Chung F, Angus S, Apfel CC, Bergese SD, Candiotti KA, Chan MT, Davis PJ, Hooper VD, Lagoo-Deenadayalan S, Myles P, Nezat G, Philip BK, Tramèr MR; Society for Ambulatory Anesthesia
Anesth Analg 2014 Jan;118(1):85-113. doi: 10.1213/ANE.0000000000000002. PMID: 24356162

Therapy

Weibel S, Rücker G, Eberhart LH, Pace NL, Hartl HM, Jordan OL, Mayer D, Riemer M, Schaefer MS, Raj D, Backhaus I, Helf A, Schlesinger T, Kienbaum P, Kranke P
Cochrane Database Syst Rev 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. PMID: 33075160Free PMC Article
Brinck EC, Tiippana E, Heesen M, Bell RF, Straube S, Moore RA, Kontinen V
Cochrane Database Syst Rev 2018 Dec 20;12(12):CD012033. doi: 10.1002/14651858.CD012033.pub4. PMID: 30570761Free PMC Article
Hines S, Steels E, Chang A, Gibbons K
Cochrane Database Syst Rev 2018 Mar 10;3(3):CD007598. doi: 10.1002/14651858.CD007598.pub3. PMID: 29523018Free PMC Article
Carlisle J, Stevenson CA
Cochrane Database Syst Rev 2017 Jul 17;7(7):CD004125. doi: 10.1002/14651858.CD004125.pub3. PMID: 28715610Free PMC Article
Apfel CC, Heidrich FM, Jukar-Rao S, Jalota L, Hornuss C, Whelan RP, Zhang K, Cakmakkaya OS
Br J Anaesth 2012 Nov;109(5):742-53. Epub 2012 Oct 3 doi: 10.1093/bja/aes276. PMID: 23035051

Prognosis

Lee DC, Vetter TR, Dobyns JB, Crump SJ, Benz DL, Short RT, Parks DA, Beasley TM, Liwo AN
Anesth Analg 2023 Sep 1;137(3):665-675. Epub 2023 May 19 doi: 10.1213/ANE.0000000000006509. PMID: 37205607
Kovac AL
Paediatr Drugs 2021 Jan;23(1):11-37. Epub 2020 Oct 27 doi: 10.1007/s40272-020-00424-0. PMID: 33108649
Ma K, Wu X, Chen Y, Yuan H
J Int Med Res 2019 May;47(5):2026-2033. Epub 2019 Mar 18 doi: 10.1177/0300060519835700. PMID: 30885027Free PMC Article
Wildes TS, Mickle AM, Ben Abdallah A, Maybrier HR, Oberhaus J, Budelier TP, Kronzer A, McKinnon SL, Park D, Torres BA, Graetz TJ, Emmert DA, Palanca BJ, Goswami S, Jordan K, Lin N, Fritz BA, Stevens TW, Jacobsohn E, Schmitt EM, Inouye SK, Stark S, Lenze EJ, Avidan MS; ENGAGES Research Group
JAMA 2019 Feb 5;321(5):473-483. doi: 10.1001/jama.2018.22005. PMID: 30721296Free PMC Article
Manahan MA, Johnson DJ, Gutowski KA, Bonawitz SC, Ellsworth WA 4th, Zielinski M, Thomsen RW, Basu CB
Plast Reconstr Surg 2018 Jan;141(1):214-222. doi: 10.1097/PRS.0000000000003924. PMID: 29280884

Clinical prediction guides

Oh SK, Lim BG, Won YJ, Lee DK, Kim SS
J Clin Anesth 2022 Jun;78:110647. Epub 2022 Jan 11 doi: 10.1016/j.jclinane.2022.110647. PMID: 35030493
Elvir-Lazo OL, White PF, Yumul R, Cruz Eng H
F1000Res 2020;9 Epub 2020 Aug 13 doi: 10.12688/f1000research.21832.1. PMID: 32913634Free PMC Article
Grape S, Kirkham KR, Frauenknecht J, Albrecht E
Anaesthesia 2019 Jun;74(6):793-800. Epub 2019 Apr 5 doi: 10.1111/anae.14657. PMID: 30950522
Veiga-Gil L, Pueyo J, López-Olaondo L
Rev Esp Anestesiol Reanim 2017 Apr;64(4):223-232. Epub 2016 Dec 29 doi: 10.1016/j.redar.2016.10.001. PMID: 28041609
Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N
Anesthesiology 1999 Sep;91(3):693-700. doi: 10.1097/00000542-199909000-00022. PMID: 10485781

Recent systematic reviews

Feenstra ML, Jansen S, Eshuis WJ, van Berge Henegouwen MI, Hollmann MW, Hermanides J
J Clin Anesth 2023 Nov;90:111215. Epub 2023 Jul 27 doi: 10.1016/j.jclinane.2023.111215. PMID: 37515877
Xuan C, Yan W, Wang D, Li C, Ma H, Mueller A, Chin V, Houle TT, Wang J
Br J Anaesth 2022 Dec;129(6):946-958. Epub 2022 Oct 26 doi: 10.1016/j.bja.2022.08.038. PMID: 36404458
Gan TJ, Jin Z, Meyer TA
Anesth Analg 2022 Nov 1;135(5):986-1000. Epub 2022 Sep 1 doi: 10.1213/ANE.0000000000006126. PMID: 36048730
Weibel S, Rücker G, Eberhart LH, Pace NL, Hartl HM, Jordan OL, Mayer D, Riemer M, Schaefer MS, Raj D, Backhaus I, Helf A, Schlesinger T, Kienbaum P, Kranke P
Cochrane Database Syst Rev 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. PMID: 33075160Free PMC Article
Hines S, Steels E, Chang A, Gibbons K
Cochrane Database Syst Rev 2018 Mar 10;3(3):CD007598. doi: 10.1002/14651858.CD007598.pub3. PMID: 29523018Free PMC Article

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