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Hemorrhage of pancreas

MedGen UID:
99269
•Concept ID:
C0521613
•
Pathologic Function
Synonym: Pancreatic Hemorrhage
SNOMED CT: Hemorrhage of pancreas (95562002)

Definition

Bleeding originating from the pancreas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHemorrhage of pancreas

Professional guidelines

PubMed

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Acute Pancreatitis: Diagnosis and Treatment.
Szatmary P, Grammatikopoulos T, Cai W, Huang W, Mukherjee R, Halloran C, Beyer G, Sutton R
Drugs 2022 Aug;82(12):1251-1276. Epub 2022 Sep 8 doi: 10.1007/s40265-022-01766-4. PMID: 36074322Free PMC Article
Diagnosis and management of insulinoma.
Okabayashi T, Shima Y, Sumiyoshi T, Kozuki A, Ito S, Ogawa Y, Kobayashi M, Hanazaki K
World J Gastroenterol 2013 Feb 14;19(6):829-37. doi: 10.3748/wjg.v19.i6.829. PMID: 23430217Free PMC Article

Recent clinical studies

Etiology

Management of postoperative pancreatic fistula after pancreaticoduodenectomy.
Malgras B, Dokmak S, Aussilhou B, Pocard M, Sauvanet A
J Visc Surg 2023 Feb;160(1):39-51. Epub 2023 Jan 24 doi: 10.1016/j.jviscsurg.2023.01.002. PMID: 36702720
Hemosuccus Pancreaticus.
Shetty S, Shenoy S, Costello R, Adeel MY, Arora A
J Ayub Med Coll Abbottabad 2019 Oct-Dec;31(4):622-626. PMID: 31933323
Inflammation and Pancreatic Cancer: Focus on Metabolism, Cytokines, and Immunity.
Padoan A, Plebani M, Basso D
Int J Mol Sci 2019 Feb 5;20(3) doi: 10.3390/ijms20030676. PMID: 30764482Free PMC Article
A prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy.
Callery MP, Pratt WB, Kent TS, Chaikof EL, Vollmer CM Jr
J Am Coll Surg 2013 Jan;216(1):1-14. Epub 2012 Nov 2 doi: 10.1016/j.jamcollsurg.2012.09.002. PMID: 23122535
Hypothermia.
Turk EE
Forensic Sci Med Pathol 2010 Jun;6(2):106-15. Epub 2010 Feb 12 doi: 10.1007/s12024-010-9142-4. PMID: 20151230

Diagnosis

Novel Circulating and Tissue Monocytes as Well as Macrophages in Pancreatitis and Recovery.
Manohar M, Jones EK, Rubin SJS, Subrahmanyam PB, Swaminathan G, Mikhail D, Bai L, Singh G, Wei Y, Sharma V, Siebert JC, Maecker HT, Husain SZ, Park WG, Pandol SJ, Habtezion A
Gastroenterology 2021 Dec;161(6):2014-2029.e14. Epub 2021 Aug 25 doi: 10.1053/j.gastro.2021.08.033. PMID: 34450180Free PMC Article
Hemosuccus Pancreaticus.
Shetty S, Shenoy S, Costello R, Adeel MY, Arora A
J Ayub Med Coll Abbottabad 2019 Oct-Dec;31(4):622-626. PMID: 31933323
Tranexamic acid for treatment and prophylaxis of bleeding and hyperfibrinolysis.
Pabinger I, Fries D, Schöchl H, Streif W, Toller W
Wien Klin Wochenschr 2017 May;129(9-10):303-316. Epub 2017 Apr 21 doi: 10.1007/s00508-017-1194-y. PMID: 28432428Free PMC Article
Postmortem diagnosis of hypothermia.
Palmiere C, Teresiński G, Hejna P
Int J Legal Med 2014 Jul;128(4):607-14. Epub 2014 Feb 21 doi: 10.1007/s00414-014-0977-1. PMID: 24557588
Pancreatic pseudocysts.
Elliott DW
Surg Clin North Am 1975 Apr;55(2):339-62. doi: 10.1016/s0039-6109(16)40585-2. PMID: 1093266

Therapy

Management of postoperative pancreatic fistula after pancreaticoduodenectomy.
Malgras B, Dokmak S, Aussilhou B, Pocard M, Sauvanet A
J Visc Surg 2023 Feb;160(1):39-51. Epub 2023 Jan 24 doi: 10.1016/j.jviscsurg.2023.01.002. PMID: 36702720
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma.
Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL, Maitra A, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR Jr
CA Cancer J Clin 2020 Sep;70(5):375-403. Epub 2020 Jul 19 doi: 10.3322/caac.21626. PMID: 32683683Free PMC Article
Understanding the mechanisms of reversal of type 2 diabetes.
Taylor R, Al-Mrabeh A, Sattar N
Lancet Diabetes Endocrinol 2019 Sep;7(9):726-736. Epub 2019 May 13 doi: 10.1016/S2213-8587(19)30076-2. PMID: 31097391
Nutritional and Metabolic Derangements in Pancreatic Cancer and Pancreatic Resection.
Gilliland TM, Villafane-Ferriol N, Shah KP, Shah RM, Tran Cao HS, Massarweh NN, Silberfein EJ, Choi EA, Hsu C, McElhany AL, Barakat O, Fisher W, Van Buren G
Nutrients 2017 Mar 7;9(3) doi: 10.3390/nu9030243. PMID: 28272344Free PMC Article
Efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis: systematic review and meta-analysis.
de la Iglesia-García D, Huang W, Szatmary P, Baston-Rey I, Gonzalez-Lopez J, Prada-Ramallal G, Mukherjee R, Nunes QM, Domínguez-Muñoz JE, Sutton R; NIHR Pancreas Biomedical Research Unit Patient Advisory Group
Gut 2017 Aug;66(8):1354-1355. Epub 2016 Dec 9 doi: 10.1136/gutjnl-2016-312529. PMID: 27941156Free PMC Article

Prognosis

Perioperative safety and prognosis following parenchyma-preserving surgery for solid pseudopapillary neoplasm of the pancreas.
Gao Y, Guo F, Lu Z, Xi C, Wei J, Jiang K, Miao Y, Wu J, Chen J
World J Surg Oncol 2023 Mar 31;21(1):119. doi: 10.1186/s12957-023-03003-y. PMID: 37004027Free PMC Article
Management of postoperative pancreatic fistula after pancreaticoduodenectomy.
Malgras B, Dokmak S, Aussilhou B, Pocard M, Sauvanet A
J Visc Surg 2023 Feb;160(1):39-51. Epub 2023 Jan 24 doi: 10.1016/j.jviscsurg.2023.01.002. PMID: 36702720
Novel Circulating and Tissue Monocytes as Well as Macrophages in Pancreatitis and Recovery.
Manohar M, Jones EK, Rubin SJS, Subrahmanyam PB, Swaminathan G, Mikhail D, Bai L, Singh G, Wei Y, Sharma V, Siebert JC, Maecker HT, Husain SZ, Park WG, Pandol SJ, Habtezion A
Gastroenterology 2021 Dec;161(6):2014-2029.e14. Epub 2021 Aug 25 doi: 10.1053/j.gastro.2021.08.033. PMID: 34450180Free PMC Article
Autophagy, Inflammation, and Immune Dysfunction in the Pathogenesis of Pancreatitis.
Gukovskaya AS, Gukovsky I, Algül H, Habtezion A
Gastroenterology 2017 Nov;153(5):1212-1226. Epub 2017 Sep 14 doi: 10.1053/j.gastro.2017.08.071. PMID: 28918190Free PMC Article
Pancreatitis: Preventing catastrophic haemorrhage.
Evans RP, Mourad MM, Pall G, Fisher SG, Bramhall SR
World J Gastroenterol 2017 Aug 14;23(30):5460-5468. doi: 10.3748/wjg.v23.i30.5460. PMID: 28852306Free PMC Article

Clinical prediction guides

Expression of PD-L1 and VISTA in Intraductal Papillary Mucinous Neoplasm With Associated Invasive Carcinoma of the Pancreas.
Mo S, Zou L, Hu Y, Chang X, Chen J
Mod Pathol 2023 Sep;36(9):100223. Epub 2023 May 25 doi: 10.1016/j.modpat.2023.100223. PMID: 37244388
Management of postoperative pancreatic fistula after pancreaticoduodenectomy.
Malgras B, Dokmak S, Aussilhou B, Pocard M, Sauvanet A
J Visc Surg 2023 Feb;160(1):39-51. Epub 2023 Jan 24 doi: 10.1016/j.jviscsurg.2023.01.002. PMID: 36702720
Safety of Irreversible Electroporation Ablation of the Pancreas.
Lee EW, Shahrouki P, Peterson S, Tafti BA, Ding PX, Kee ST
Pancreas 2021 Oct 1;50(9):1281-1286. doi: 10.1097/MPA.0000000000001916. PMID: 34860812
Novel Circulating and Tissue Monocytes as Well as Macrophages in Pancreatitis and Recovery.
Manohar M, Jones EK, Rubin SJS, Subrahmanyam PB, Swaminathan G, Mikhail D, Bai L, Singh G, Wei Y, Sharma V, Siebert JC, Maecker HT, Husain SZ, Park WG, Pandol SJ, Habtezion A
Gastroenterology 2021 Dec;161(6):2014-2029.e14. Epub 2021 Aug 25 doi: 10.1053/j.gastro.2021.08.033. PMID: 34450180Free PMC Article
A prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy.
Callery MP, Pratt WB, Kent TS, Chaikof EL, Vollmer CM Jr
J Am Coll Surg 2013 Jan;216(1):1-14. Epub 2012 Nov 2 doi: 10.1016/j.jamcollsurg.2012.09.002. PMID: 23122535

Recent systematic reviews

Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Guideline Update.
Key NS, Khorana AA, Kuderer NM, Bohlke K, Lee AYY, Arcelus JI, Wong SL, Balaban EP, Flowers CR, Gates LE, Kakkar AK, Tempero MA, Gupta S, Lyman GH, Falanga A
J Clin Oncol 2023 Jun 1;41(16):3063-3071. Epub 2023 Apr 19 doi: 10.1200/JCO.23.00294. PMID: 37075273
A systematic review and meta-analyses of regional perfusion in donation after circulatory death solid organ transplantation.
De Beule J, Vandendriessche K, Pengel LHM, Bellini MI, Dark JH, Hessheimer AJ, Kimenai HJAN, Knight SR, Neyrinck AP, Paredes D, Watson CJE, Rega F, Jochmans I
Transpl Int 2021 Nov;34(11):2046-2060. Epub 2021 Oct 19 doi: 10.1111/tri.14121. PMID: 34570380
Safety and Efficacy of Teplizumab for Treatment of Type One Diabetes Mellitus: A Systematic Review and Meta-Analysis.
Nourelden AZ, Elshanbary AA, El-Sherif L, Benmelouka AY, Rohim HI, Helmy SK, Sayed MK, Ismail A, Ali AS, Ragab KM, Zaazouee MS
Endocr Metab Immune Disord Drug Targets 2021;21(10):1895-1904. doi: 10.2174/1871530320999201209222921. PMID: 33302842
Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century.
Hansen CC, Søreide K
Medicine (Baltimore) 2018 Aug;97(35):e12154. doi: 10.1097/MD.0000000000012154. PMID: 30170459Free PMC Article
Efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis: systematic review and meta-analysis.
de la Iglesia-García D, Huang W, Szatmary P, Baston-Rey I, Gonzalez-Lopez J, Prada-Ramallal G, Mukherjee R, Nunes QM, Domínguez-Muñoz JE, Sutton R; NIHR Pancreas Biomedical Research Unit Patient Advisory Group
Gut 2017 Aug;66(8):1354-1355. Epub 2016 Dec 9 doi: 10.1136/gutjnl-2016-312529. PMID: 27941156Free PMC Article

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