U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Chronic hepatitis B virus infection

MedGen UID:
99834
Concept ID:
C0524909
Disease or Syndrome
Synonyms: Chronic Hepatitis B; Chronic Hepatitis B Virus Infection; Hepatitis B Virus Infection, Chronic; Hepatitis B, Chronic
SNOMED CT: Chronic type B viral hepatitis (61977001); Chronic viral hepatitis B (61977001)
 
Monarch Initiative: MONDO:0005366

Definition

Chronic form of hepatitis B infection. [from MONDO]

Professional guidelines

PubMed

Charre C, Levrero M, Zoulim F, Scholtès C
Antiviral Res 2019 Sep;169:104553. Epub 2019 Jul 6 doi: 10.1016/j.antiviral.2019.104553. PMID: 31288041
Liu LZ, Sun J, Hou J, Chan HLY
Expert Rev Gastroenterol Hepatol 2018 Nov;12(11):1153-1166. Epub 2018 Oct 5 doi: 10.1080/17474124.2018.1530986. PMID: 30269597
Yuen MF, Ahn SH, Chen DS, Chen PJ, Dusheiko GM, Hou JL, Maddrey WC, Mizokami M, Seto WK, Zoulim F, Lai CL
J Clin Gastroenterol 2016 Apr;50(4):286-94. doi: 10.1097/MCG.0000000000000478. PMID: 26840752

Recent clinical studies

Etiology

Conners EE, Panagiotakopoulos L, Hofmeister MG, Spradling PR, Hagan LM, Harris AM, Rogers-Brown JS, Wester C, Nelson NP; Contributors
MMWR Recomm Rep 2023 Mar 10;72(1):1-25. doi: 10.15585/mmwr.rr7201a1. PMID: 36893044Free PMC Article
Shen Y, Wu SD, Chen Y, Li XY, Zhu Q, Nakayama K, Zhang WQ, Weng CZ, Zhang J, Wang HK, Wu J, Jiang W
Gut Microbes 2023 Jan-Dec;15(1):2155018. doi: 10.1080/19490976.2022.2155018. PMID: 36519342Free PMC Article
Seto WK, Lo YR, Pawlotsky JM, Yuen MF
Lancet 2018 Nov 24;392(10161):2313-2324. doi: 10.1016/S0140-6736(18)31865-8. PMID: 30496122
Bertoletti A, Le Bert N
Gut Liver 2018 Sep 15;12(5):497-507. doi: 10.5009/gnl17233. PMID: 29316747Free PMC Article
Schweitzer A, Horn J, Mikolajczyk RT, Krause G, Ott JJ
Lancet 2015 Oct 17;386(10003):1546-55. Epub 2015 Jul 28 doi: 10.1016/S0140-6736(15)61412-X. PMID: 26231459

Diagnosis

Conners EE, Panagiotakopoulos L, Hofmeister MG, Spradling PR, Hagan LM, Harris AM, Rogers-Brown JS, Wester C, Nelson NP; Contributors
MMWR Recomm Rep 2023 Mar 10;72(1):1-25. doi: 10.15585/mmwr.rr7201a1. PMID: 36893044Free PMC Article
Su S, Wong WC, Zou Z, Cheng DD, Ong JJ, Chan P, Ji F, Yuen MF, Zhuang G, Seto WK, Zhang L
Lancet Glob Health 2022 Feb;10(2):e278-e287. doi: 10.1016/S2214-109X(21)00517-9. PMID: 35063115Free PMC Article
Stalla F, Armandi A, Marinoni C, Fagoonee S, Pellicano R, Caviglia GP
Minerva Gastroenterol (Torino) 2022 Sep;68(3):306-318. Epub 2021 Apr 19 doi: 10.23736/S2724-5985.21.02911-9. PMID: 33871225
Luo P, Yin P, Hua R, Tan Y, Li Z, Qiu G, Yin Z, Xie X, Wang X, Chen W, Zhou L, Wang X, Li Y, Chen H, Gao L, Lu X, Wu T, Wang H, Niu J, Xu G
Hepatology 2018 Feb;67(2):662-675. Epub 2018 Jan 2 doi: 10.1002/hep.29561. PMID: 28960374Free PMC Article
McMahon BJ
Med Clin North Am 2014 Jan;98(1):39-54. Epub 2013 Oct 20 doi: 10.1016/j.mcna.2013.08.004. PMID: 24266913

Therapy

Shen Y, Wu SD, Chen Y, Li XY, Zhu Q, Nakayama K, Zhang WQ, Weng CZ, Zhang J, Wang HK, Wu J, Jiang W
Gut Microbes 2023 Jan-Dec;15(1):2155018. doi: 10.1080/19490976.2022.2155018. PMID: 36519342Free PMC Article
Ji D, Chen Y, Bi J, Shang Q, Liu H, Wang JB, Tan L, Wang J, Chen Y, Li Q, Long Q, Song L, Jiang L, Xiao G, Yu Z, Chen L, Wang X, Chen D, Li Z, Dong Z, Yang Y
J Hepatol 2022 Dec;77(6):1515-1524. Epub 2022 Aug 18 doi: 10.1016/j.jhep.2022.07.018. PMID: 35985545
Seto WK, Lo YR, Pawlotsky JM, Yuen MF
Lancet 2018 Nov 24;392(10161):2313-2324. doi: 10.1016/S0140-6736(18)31865-8. PMID: 30496122
Bertoletti A, Le Bert N
Gut Liver 2018 Sep 15;12(5):497-507. doi: 10.5009/gnl17233. PMID: 29316747Free PMC Article
Adinolfi LE, Nevola R, Rinaldi L, Romano C, Giordano M
Clin Liver Dis 2017 Aug;21(3):517-534. Epub 2017 Apr 25 doi: 10.1016/j.cld.2017.03.007. PMID: 28689590

Prognosis

Shen Y, Wu SD, Chen Y, Li XY, Zhu Q, Nakayama K, Zhang WQ, Weng CZ, Zhang J, Wang HK, Wu J, Jiang W
Gut Microbes 2023 Jan-Dec;15(1):2155018. doi: 10.1080/19490976.2022.2155018. PMID: 36519342Free PMC Article
Ye X, Wang L, Nie M, Wang Y, Dong S, Ren W, Li G, Li ZM, Wu K, Pan-Hammarström Q
Cell Rep 2022 Apr 19;39(3):110713. doi: 10.1016/j.celrep.2022.110713. PMID: 35443163
Chitnis AS, Cheung R, Gish RG, Wong RJ
J Immigr Minor Health 2021 Dec;23(6):1267-1279. Epub 2021 Jun 23 doi: 10.1007/s10903-021-01231-6. PMID: 34160726
Dandri M
Semin Immunopathol 2020 Apr;42(2):173-185. Epub 2020 Mar 17 doi: 10.1007/s00281-020-00780-6. PMID: 32185454Free PMC Article
Busch K, Thimme R
Med Microbiol Immunol 2015 Feb;204(1):5-10. Epub 2014 Dec 25 doi: 10.1007/s00430-014-0369-7. PMID: 25540037

Clinical prediction guides

Liu Z, Lin C, Mao X, Guo C, Suo C, Zhu D, Jiang W, Li Y, Fan J, Song C, Zhang T, Jin L, De Martel C, Clifford GM, Chen X
Gut 2023 Nov 24;72(12):2354-2363. doi: 10.1136/gutjnl-2023-330691. PMID: 37798085Free PMC Article
Ji D, Chen Y, Bi J, Shang Q, Liu H, Wang JB, Tan L, Wang J, Chen Y, Li Q, Long Q, Song L, Jiang L, Xiao G, Yu Z, Chen L, Wang X, Chen D, Li Z, Dong Z, Yang Y
J Hepatol 2022 Dec;77(6):1515-1524. Epub 2022 Aug 18 doi: 10.1016/j.jhep.2022.07.018. PMID: 35985545
Ye X, Wang L, Nie M, Wang Y, Dong S, Ren W, Li G, Li ZM, Wu K, Pan-Hammarström Q
Cell Rep 2022 Apr 19;39(3):110713. doi: 10.1016/j.celrep.2022.110713. PMID: 35443163
Adinolfi LE, Nevola R, Rinaldi L, Romano C, Giordano M
Clin Liver Dis 2017 Aug;21(3):517-534. Epub 2017 Apr 25 doi: 10.1016/j.cld.2017.03.007. PMID: 28689590
Yuen MF, Ahn SH, Chen DS, Chen PJ, Dusheiko GM, Hou JL, Maddrey WC, Mizokami M, Seto WK, Zoulim F, Lai CL
J Clin Gastroenterol 2016 Apr;50(4):286-94. doi: 10.1097/MCG.0000000000000478. PMID: 26840752

Recent systematic reviews

Liu Z, Lin C, Mao X, Guo C, Suo C, Zhu D, Jiang W, Li Y, Fan J, Song C, Zhang T, Jin L, De Martel C, Clifford GM, Chen X
Gut 2023 Nov 24;72(12):2354-2363. doi: 10.1136/gutjnl-2023-330691. PMID: 37798085Free PMC Article
Yendewa GA, Wang GM, James PB, Massaquoi SPE, Yendewa SA, Ghazawi M, Babawo LS, Ocama P, Russell JBW, Deen GF, Sahr F, Kabba M, Tatsuoka C, Lakoh S, Salata RA
Am J Trop Med Hyg 2023 Jul 5;109(1):105-114. Epub 2023 May 22 doi: 10.4269/ajtmh.22-0711. PMID: 37217165Free PMC Article
Ma X, Sun D, Li C, Ying J, Yan Y
J Med Virol 2018 Jan;90(1):93-100. Epub 2017 Sep 12 doi: 10.1002/jmv.24927. PMID: 28851115
Leroi C, Adam P, Khamduang W, Kawilapat S, Ngo-Giang-Huong N, Ongwandee S, Jiamsiri S, Jourdain G
Int J Infect Dis 2016 Oct;51:36-43. Epub 2016 Aug 28 doi: 10.1016/j.ijid.2016.08.017. PMID: 27580678
Schweitzer A, Horn J, Mikolajczyk RT, Krause G, Ott JJ
Lancet 2015 Oct 17;386(10003):1546-55. Epub 2015 Jul 28 doi: 10.1016/S0140-6736(15)61412-X. PMID: 26231459

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...