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1.

Mismatch repair cancer syndrome 1

Lynch syndrome is characterized by an increased risk for colorectal cancer (CRC) and cancers of the endometrium, ovary, stomach, small bowel, urinary tract, biliary tract, brain (usually glioblastoma), skin (sebaceous adenomas, sebaceous carcinomas, and keratoacanthomas), pancreas, and prostate. Cancer risks and age of onset vary depending on the associated gene. Several other cancer types have been reported to occur in individuals with Lynch syndrome (e.g., breast, sarcomas, adrenocortical carcinoma). However, the data are not sufficient to demonstrate that the risk of developing these cancers is increased in individuals with Lynch syndrome. [from GeneReviews]

MedGen UID:
1748029
Concept ID:
C5399763
Disease or Syndrome
2.

Adenocarcinoma of the small intestine

A malignant epithelial tumor with a glandular organization that originates in the small intestine. [from HPO]

MedGen UID:
82984
Concept ID:
C0278803
Neoplastic Process

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