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Choroidal melanoma

MedGen UID:
138064
Concept ID:
C0346388
Neoplastic Process
Synonyms: Choroid Malignant Melanoma; choroid malignant melanoma; Choroid Melanoma; choroid melanoma; Choroidal Melanoma; choroidal melanoma; malignant choroid melanoma; Malignant melanoma of choroid; Malignant Melanoma of Choroid; malignant melanoma of choroid; Malignant Melanoma of the Choroid; malignant melanoma of the choroid; melanoma (disease) of optic choroid; Melanoma of Choroid; melanoma of choroid; Melanoma of the Choroid; melanoma of the choroid; optic choroid melanoma; optic choroid melanoma (disease)
SNOMED CT: Malignant melanoma of choroid (255021005)
 
HPO: HP:0012054
Monarch Initiative: MONDO:0003878

Definition

Malignant tumor of melanocytes of the choroid. The classic appearance of choroidal melanoma is a pigmented dome-shaped or collar button-shaped tumor with an associated exudative retinal detachment. Choroidal melanoma is usually pigmented, but can be variably pigmented and even amelanotic (non-pigmented). [from HPO]

Professional guidelines

PubMed

Weis E, Surgeoner B, Salopek TG, Cheng T, Hyrcza M, Kostaras X, Larocque M, McKinnon G, McWhae J, Menon G, Monzon J, Murtha AD, Walker J, Temple-Oberle C
Curr Oncol 2023 Dec 20;31(1):24-41. doi: 10.3390/curroncol31010002. PMID: 38275828Free PMC Article
Maheshwari A, Finger PT
Surv Ophthalmol 2023 Mar-Apr;68(2):211-224. Epub 2022 May 27 doi: 10.1016/j.survophthal.2022.05.002. PMID: 35644256
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article

Recent clinical studies

Etiology

Wallace A, Krishna Y, Coupland SE, Heimann H, Diafas A, Hussain RN
Ophthalmology 2023 Oct;130(10):1046-1052. Epub 2023 May 13 doi: 10.1016/j.ophtha.2023.05.009. PMID: 37182744
Davila JR, Mruthyunjaya P
F1000Res 2019;8 Epub 2019 Oct 1 doi: 10.12688/f1000research.19979.1. PMID: 31602297Free PMC Article
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Singh AD
Eye (Lond) 2013 Feb;27(2):190-8. Epub 2012 Dec 14 doi: 10.1038/eye.2012.258. PMID: 23238445Free PMC Article
Sallam A, Hungerford J
Br J Hosp Med (Lond) 2007 Dec;68(12):669-73. doi: 10.12968/hmed.2007.68.12.669. PMID: 18186408

Diagnosis

Maheshwari A, Finger PT
Cancer Metastasis Rev 2018 Dec;37(4):677-690. doi: 10.1007/s10555-018-9762-9. PMID: 30203109
Hamza HS, Elhusseiny AM
Middle East Afr J Ophthalmol 2018 Apr-Jun;25(2):65-70. doi: 10.4103/meajo.MEAJO_73_18. PMID: 30122851Free PMC Article
Sallam A, Hungerford J
Br J Hosp Med (Lond) 2007 Dec;68(12):669-73. doi: 10.12968/hmed.2007.68.12.669. PMID: 18186408
Grin-Jorgensen C, Berke A, Grin M
Dermatol Clin 1992 Oct;10(4):663-8. PMID: 1395150
Shields CL, Shields JA, Augsburger JJ
Surv Ophthalmol 1988 Jul-Aug;33(1):17-27. doi: 10.1016/0039-6257(88)90069-0. PMID: 3051466

Therapy

Yordi S, Soto H, Bowen RC, Singh AD
Surv Ophthalmol 2021 Jul-Aug;66(4):552-559. Epub 2021 Jan 2 doi: 10.1016/j.survophthal.2020.09.006. PMID: 33400941
Ooi KG, Khoo P, Vaclavik V, Watson SL
Surv Ophthalmol 2019 May-Jun;64(3):401-432. Epub 2019 Jan 28 doi: 10.1016/j.survophthal.2019.01.013. PMID: 30703407
Vasalaki M, Fabian ID, Reddy MA, Cohen VM, Sagoo MS
Br Med Bull 2017 Jan 1;121(1):107-119. doi: 10.1093/bmb/ldw053. PMID: 28069617
Kawczyk-Krupka A, Bugaj AM, Latos W, Zaremba K, Sieroń A
Photodiagnosis Photodyn Ther 2013 Dec;10(4):503-9. Epub 2013 Jun 17 doi: 10.1016/j.pdpdt.2013.05.006. PMID: 24284103
Finger PT
Surv Ophthalmol 1997 Nov-Dec;42(3):215-32. doi: 10.1016/s0039-6257(97)00088-x. PMID: 9406368

Prognosis

Wespiser M, Neidhardt E, Negrier S
Cancer Treat Rev 2023 Sep;119:102599. Epub 2023 Jul 7 doi: 10.1016/j.ctrv.2023.102599. PMID: 37473516
Wallace A, Krishna Y, Coupland SE, Heimann H, Diafas A, Hussain RN
Ophthalmology 2023 Oct;130(10):1046-1052. Epub 2023 May 13 doi: 10.1016/j.ophtha.2023.05.009. PMID: 37182744
Lemaître S, Lévy-Gabriel C, Desjardins L, Plancher C, Asselain B, Vincent-Salomon A, Lumbroso-Le Rouic L, Dendale R, Rouzier R, Delacroix S, Cassoux N
Acta Ophthalmol 2016 Nov;94(7):e652-e660. Epub 2016 Mar 24 doi: 10.1111/aos.12984. PMID: 27009598
Grin-Jorgensen C, Berke A, Grin M
Dermatol Clin 1992 Oct;10(4):663-8. PMID: 1395150
Shields CL, Shields JA, Augsburger JJ
Surv Ophthalmol 1988 Jul-Aug;33(1):17-27. doi: 10.1016/0039-6257(88)90069-0. PMID: 3051466

Clinical prediction guides

Wallace A, Krishna Y, Coupland SE, Heimann H, Diafas A, Hussain RN
Ophthalmology 2023 Oct;130(10):1046-1052. Epub 2023 May 13 doi: 10.1016/j.ophtha.2023.05.009. PMID: 37182744
Jouhi S, Al-Jamal RT, Täll M, Eskelin S, Kivelä TT
Br J Ophthalmol 2023 Mar;107(3):412-417. Epub 2021 Oct 19 doi: 10.1136/bjophthalmol-2020-318658. PMID: 34666992
Yordi S, Soto H, Bowen RC, Singh AD
Surv Ophthalmol 2021 Jul-Aug;66(4):552-559. Epub 2021 Jan 2 doi: 10.1016/j.survophthal.2020.09.006. PMID: 33400941
Maheshwari A, Finger PT
Cancer Metastasis Rev 2018 Dec;37(4):677-690. doi: 10.1007/s10555-018-9762-9. PMID: 30203109
Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933

Recent systematic reviews

Romano MR, Catania F, Confalonieri F, Zollet P, Allegrini D, Sergenti J, Lanza FB, Ferrara M, Angi M
Int J Mol Sci 2021 Sep 17;22(18) doi: 10.3390/ijms221810066. PMID: 34576231Free PMC Article
Badawi AH, Semidey VA, Magliyah M, Al-Dhibi H
Middle East Afr J Ophthalmol 2020 Jan-Mar;27(1):4-9. Epub 2020 Apr 29 doi: 10.4103/meajo.MEAJO_85_20. PMID: 32549717Free PMC Article
Singh AD, Kalyani P, Topham A
Ophthalmology 2005 Oct;112(10):1784-9. doi: 10.1016/j.ophtha.2005.06.011. PMID: 16154197

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