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Erythematous papule

MedGen UID:
834002
Concept ID:
C0747241
Finding
Synonym: Erythematous papules
 
HPO: HP:0030350

Definition

A circumscribed, solid elevation of skin with no visible fluid that is reddish (erythematous) in color. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Erythematous papule

Conditions with this feature

Xeroderma pigmentosum group A
MedGen UID:
82775
Concept ID:
C0268135
Disease or Syndrome
Xeroderma pigmentosum (XP) is characterized by: Acute sun sensitivity (severe sunburn with blistering, persistent erythema on minimal sun exposure) with marked freckle-like pigmentation of the face before age two years; Sunlight-induced ocular involvement (photophobia, severe keratitis, atrophy of the skin of the lids, ocular surface neoplasms); Greatly increased risk of sunlight-induced cutaneous neoplasms (basal cell carcinoma, squamous cell carcinoma, melanoma) within the first decade of life. Approximately 25% of affected individuals have neurologic manifestations (acquired microcephaly, diminished or absent deep tendon stretch reflexes, progressive sensorineural hearing loss, progressive cognitive impairment, and ataxia). The most common causes of death are skin cancer, neurologic degeneration, and internal cancer. The median age at death in persons with XP with neurodegeneration (29 years) was found to be younger than that in persons with XP without neurodegeneration (37 years).
Severe combined immunodeficiency due to DCLRE1C deficiency
MedGen UID:
355454
Concept ID:
C1865370
Disease or Syndrome
Severe combined immunodeficiency (SCID) due to DCLRE1C deficiency is a type of SCID (see this term) characterized by severe and recurrent infections, diarrhea, failure to thrive, and cell sensitivity to ionizing radiation.

Professional guidelines

PubMed

Shoimer I, Rosen N, Muhn C
Skin Therapy Lett 2010 May;15(5):5-7. PMID: 20505896

Recent clinical studies

Etiology

Kaur H, Nikam BP, Jamale VP, Kale MS
Indian J Dermatol Venereol Leprol 2020 Mar-Apr;86(2):169-175. doi: 10.4103/ijdvl.IJDVL_650_17. PMID: 31898636
Munera-Campos M, Plana-Pla A, Quer A
JAMA Dermatol 2019 Feb 1;155(2):247-248. doi: 10.1001/jamadermatol.2018.4445. PMID: 30484827
Edlich RF, Winters KL, Britt LD, Long WB 3rd
J Long Term Eff Med Implants 2005;15(5):499-510. doi: 10.1615/jlongtermeffmedimplants.v15.i5.40. PMID: 16218899
Böstman O, Pihlajamäki H
Biomaterials 2000 Dec;21(24):2615-21. doi: 10.1016/s0142-9612(00)00129-0. PMID: 11071611
Böstman OM, Pihlajamäki HK
Clin Orthop Relat Res 2000 Feb;(371):216-27. PMID: 10693569

Diagnosis

Park HS, Ju HJ, Yoo CY, Cho U
Int J Dermatol 2022 Dec;61(12):1479-1480. Epub 2022 May 16 doi: 10.1111/ijd.16186. PMID: 35575938
Zaouak A, Salah MB, Koubaa W, Hammami H, Fenniche S
Skinmed 2019;17(2):124-126. Epub 2019 May 29 PMID: 31145066
Munera-Campos M, Plana-Pla A, Quer A
JAMA Dermatol 2019 Feb 1;155(2):247-248. doi: 10.1001/jamadermatol.2018.4445. PMID: 30484827
Rivard SSC, Crandall ML, Gibbs NF
J Spec Oper Med 2014 Spring;14(1):99-102. doi: 10.55460/XVGN-UHTJ. PMID: 24604447
Edlich RF, Winters KL, Britt LD, Long WB 3rd
J Long Term Eff Med Implants 2005;15(5):499-510. doi: 10.1615/jlongtermeffmedimplants.v15.i5.40. PMID: 16218899

Therapy

Rivard SSC, Crandall ML, Gibbs NF
J Spec Oper Med 2014 Spring;14(1):99-102. doi: 10.55460/XVGN-UHTJ. PMID: 24604447
Shoimer I, Rosen N, Muhn C
Skin Therapy Lett 2010 May;15(5):5-7. PMID: 20505896
Edlich RF, Winters KL, Britt LD, Long WB 3rd
J Long Term Eff Med Implants 2005;15(5):499-510. doi: 10.1615/jlongtermeffmedimplants.v15.i5.40. PMID: 16218899
Celebi S, Aykan U, Alagöz G, Esmerligil S
Eur J Ophthalmol 2001 Apr-Jun;11(2):171-4. doi: 10.1177/112067210101100212. PMID: 11456020
Böstman OM, Pihlajamäki HK
Clin Orthop Relat Res 2000 Feb;(371):216-27. PMID: 10693569

Prognosis

Ciaglia K, Ghawji M, Caraballo M, Sloan E
Pediatrics 2024 Mar 1;153(3) doi: 10.1542/peds.2023-063268. PMID: 38361479
Munera-Campos M, Plana-Pla A, Quer A
JAMA Dermatol 2019 Feb 1;155(2):247-248. doi: 10.1001/jamadermatol.2018.4445. PMID: 30484827
Shoimer I, Rosen N, Muhn C
Skin Therapy Lett 2010 May;15(5):5-7. PMID: 20505896
Edlich RF, Winters KL, Britt LD, Long WB 3rd
J Long Term Eff Med Implants 2005;15(5):499-510. doi: 10.1615/jlongtermeffmedimplants.v15.i5.40. PMID: 16218899
Böstman OM, Pihlajamäki HK
Clin Orthop Relat Res 2000 Feb;(371):216-27. PMID: 10693569

Clinical prediction guides

Kaur H, Nikam BP, Jamale VP, Kale MS
Indian J Dermatol Venereol Leprol 2020 Mar-Apr;86(2):169-175. doi: 10.4103/ijdvl.IJDVL_650_17. PMID: 31898636
Takamura S, Suyama T, Teraki Y
J Dermatol 2016 Sep;43(9):1067-70. Epub 2016 Mar 30 doi: 10.1111/1346-8138.13372. PMID: 27027509
Reserva J, Chamlin SL
Pediatr Ann 2014 Jan 1;43(1):e22-4. doi: 10.3928/00904481-20131223-14. PMID: 24549084
Sampaio FM, Lourenço FT, Obadia DL, Nascimento LV
An Bras Dermatol 2012 Sep-Oct;87(5):789-90. doi: 10.1590/s0365-05962012000500024. PMID: 23044580
Wani Y, Fujioka Y
Am J Dermatopathol 2009 Jul;31(5):465-7. doi: 10.1097/DAD.0b013e31818a9a76. PMID: 19542922

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