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Increased histidine

MedGen UID:
713481
•Concept ID:
C1291163
•
Finding
Synonym: Histidine above reference range
SNOMED CT: Increased histidine (124063001); Histidine above reference range (124063001)

Professional guidelines

PubMed

Histidine decarboxylase inhibitors: a novel therapeutic option for the treatment of leydigioma.
Abiuso AMB, Varela ML, Raices T, Irusta G, Lazzati JM, Besio Moreno M, Cavallotti A, Belgorosky A, Pignataro OP, Berensztein E, Mondillo C
J Endocrinol 2022 Dec 1;255(3):103-116. Epub 2022 Oct 3 doi: 10.1530/JOE-21-0419. PMID: 36069766

Recent clinical studies

Etiology

Effects of Histidine Supplementation on Global Serum and Urine (1)H NMR-based Metabolomics and Serum Amino Acid Profiles in Obese Women from a Randomized Controlled Study.
Du S, Sun S, Liu L, Zhang Q, Guo F, Li C, Feng R, Sun C
J Proteome Res 2017 Jun 2;16(6):2221-2230. Epub 2017 May 5 doi: 10.1021/acs.jproteome.7b00030. PMID: 28447460
Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease.
Yu B, Li AH, Muzny D, Veeraraghavan N, de Vries PS, Bis JC, Musani SK, Alexander D, Morrison AC, Franco OH, Uitterlinden A, Hofman A, Dehghan A, Wilson JG, Psaty BM, Gibbs R, Wei P, Boerwinkle E
Circ Cardiovasc Genet 2015 Apr;8(2):351-5. Epub 2015 Jan 8 doi: 10.1161/CIRCGENETICS.114.000697. PMID: 25575548Free PMC Article
Red cell and plasma amino acid concentrations in renal failure.
Flügel-Link RM, Jones MR, Kopple JD
JPEN J Parenter Enteral Nutr 1983 Sep-Oct;7(5):450-6. doi: 10.1177/0148607183007005450. PMID: 6685782

Diagnosis

Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease.
Jurynczyk M, Probert F, Yeo T, Tackley G, Claridge TDW, Cavey A, Woodhall MR, Arora S, Winkler T, Schiffer E, Vincent A, DeLuca G, Sibson NR, Isabel Leite M, Waters P, Anthony DC, Palace J
Acta Neuropathol Commun 2017 Dec 6;5(1):95. doi: 10.1186/s40478-017-0495-8. PMID: 29208041Free PMC Article

Therapy

Histidine kinase NME1 and NME2 are involved in TGF-β1-induced HSC activation and CCl(4)-induced liver fibrosis.
Gong H, Fan Z, Yi D, Chen J, Li Z, Guo R, Wang C, Fang W, Liu S
J Mol Histol 2020 Oct;51(5):573-581. Epub 2020 Aug 28 doi: 10.1007/s10735-020-09906-4. PMID: 32860079
Effects of Histidine Supplementation on Global Serum and Urine (1)H NMR-based Metabolomics and Serum Amino Acid Profiles in Obese Women from a Randomized Controlled Study.
Du S, Sun S, Liu L, Zhang Q, Guo F, Li C, Feng R, Sun C
J Proteome Res 2017 Jun 2;16(6):2221-2230. Epub 2017 May 5 doi: 10.1021/acs.jproteome.7b00030. PMID: 28447460
Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease.
Yu B, Li AH, Muzny D, Veeraraghavan N, de Vries PS, Bis JC, Musani SK, Alexander D, Morrison AC, Franco OH, Uitterlinden A, Hofman A, Dehghan A, Wilson JG, Psaty BM, Gibbs R, Wei P, Boerwinkle E
Circ Cardiovasc Genet 2015 Apr;8(2):351-5. Epub 2015 Jan 8 doi: 10.1161/CIRCGENETICS.114.000697. PMID: 25575548Free PMC Article
Understanding the poor iontophoretic transport of lysozyme across the skin: when high charge and high electrophoretic mobility are not enough.
Dubey S, Kalia YN
J Control Release 2014 Jun 10;183:35-42. Epub 2014 Mar 20 doi: 10.1016/j.jconrel.2014.03.027. PMID: 24657950
Comparison of the actions of acylated and desacylated ghrelin on acid secretion in the rat stomach.
Sakurada T, Ro S, Onouchi T, Ohno S, Aoyama T, Chinen K, Takabayashi H, Kato S, Takayama K, Yakabi K
J Gastroenterol 2010 Nov;45(11):1111-20. Epub 2010 Jun 23 doi: 10.1007/s00535-010-0269-6. PMID: 20571831

Prognosis

Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease.
Jurynczyk M, Probert F, Yeo T, Tackley G, Claridge TDW, Cavey A, Woodhall MR, Arora S, Winkler T, Schiffer E, Vincent A, DeLuca G, Sibson NR, Isabel Leite M, Waters P, Anthony DC, Palace J
Acta Neuropathol Commun 2017 Dec 6;5(1):95. doi: 10.1186/s40478-017-0495-8. PMID: 29208041Free PMC Article
Understanding the poor iontophoretic transport of lysozyme across the skin: when high charge and high electrophoretic mobility are not enough.
Dubey S, Kalia YN
J Control Release 2014 Jun 10;183:35-42. Epub 2014 Mar 20 doi: 10.1016/j.jconrel.2014.03.027. PMID: 24657950

Clinical prediction guides

Histidine decarboxylase inhibitors: a novel therapeutic option for the treatment of leydigioma.
Abiuso AMB, Varela ML, Raices T, Irusta G, Lazzati JM, Besio Moreno M, Cavallotti A, Belgorosky A, Pignataro OP, Berensztein E, Mondillo C
J Endocrinol 2022 Dec 1;255(3):103-116. Epub 2022 Oct 3 doi: 10.1530/JOE-21-0419. PMID: 36069766
Effects of Histidine Supplementation on Global Serum and Urine (1)H NMR-based Metabolomics and Serum Amino Acid Profiles in Obese Women from a Randomized Controlled Study.
Du S, Sun S, Liu L, Zhang Q, Guo F, Li C, Feng R, Sun C
J Proteome Res 2017 Jun 2;16(6):2221-2230. Epub 2017 May 5 doi: 10.1021/acs.jproteome.7b00030. PMID: 28447460
Understanding the poor iontophoretic transport of lysozyme across the skin: when high charge and high electrophoretic mobility are not enough.
Dubey S, Kalia YN
J Control Release 2014 Jun 10;183:35-42. Epub 2014 Mar 20 doi: 10.1016/j.jconrel.2014.03.027. PMID: 24657950
Mast cells as a possible source of Haemophilus influenzae-induced changes in plasma and lung histamine levels.
Raaijmakers JA, Terpstra GK, Kreukniet J
Int Arch Allergy Appl Immunol 1980;61(3):352-7. doi: 10.1159/000232459. PMID: 6153378

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