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Resting heart rate(RHR)

MedGen UID:
369209
•Concept ID:
C1821417
•
Finding
Synonyms: Resting heart rate, variation in; RHR
SNOMED CT: Resting heart rate (444981005)
 
Gene (location): ADRB1 (10q25.3)
 
OMIM®: 607276

Professional guidelines

PubMed

MEdical TReatment Optimization in cardiac rehabilitation (METRO study) : a French multicenter study.
Pavy B, Iliou MC, Guy JM, Tabet JY, Ponchon-Weess A, Pierre B, Blonde MC, Bire F, Paemelaere F, Bosser G, Blanc P, Gebuhrer V, Carré F; group of exercise rehabilitation sport prevention (GERSP) of the French Society of Cardiology
Ann Cardiol Angeiol (Paris) 2021 Nov;70(5):275-280. Epub 2021 Oct 9 doi: 10.1016/j.ancard.2021.08.009. PMID: 34635328
Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysis.
Kite C, Lahart IM, Afzal I, Broom DR, Randeva H, Kyrou I, Brown JE
Syst Rev 2019 Feb 12;8(1):51. doi: 10.1186/s13643-019-0962-3. PMID: 30755271Free PMC Article
Clinical update on the management of atrial fibrillation.
Danelich IM, Reed BN, Hollis IB, Cook AM, Rodgers JE
Pharmacotherapy 2013 Apr;33(4):422-46. doi: 10.1002/phar.1217. PMID: 23553811

Recent clinical studies

Etiology

Associations of resting heart rate with incident dementia, cognition, and brain structure: a prospective cohort study of UK biobank.
Deng YT, Kuo K, Wu BS, Ou YN, Yang L, Zhang YR, Huang SY, Chen SD, Guo Y, Zhang RQ, Tan L, Dong Q, Feng JF, Cheng W, Yu JT
Alzheimers Res Ther 2022 Oct 5;14(1):147. doi: 10.1186/s13195-022-01088-3. PMID: 36199126Free PMC Article
Relationship of resting heart rate and blood pressure with all-cause and cardiovascular disease mortality.
He K, Chen X, Shi Z, Shi S, Tian Q, Hu X, Song R, Bai K, Shi W, Wang J, Li H, Ding J, Geng S, Sheng X
Public Health 2022 Jul;208:80-88. Epub 2022 Jun 18 doi: 10.1016/j.puhe.2022.03.020. PMID: 35728416
Autonomic dysfunction in kidney diseases.
Lai S, Bagordo D, Perrotta AM, Gigante A, Gasperini ML, Muscaritoli M, Mazzaferro S, Cianci R
Eur Rev Med Pharmacol Sci 2020 Aug;24(16):8458-8468. doi: 10.26355/eurrev_202008_22643. PMID: 32894552
Resting heart rate and relation to disease and longevity: past, present and future.
Jensen MT
Scand J Clin Lab Invest 2019 Feb-Apr;79(1-2):108-116. Epub 2019 Feb 14 doi: 10.1080/00365513.2019.1566567. PMID: 30761923
Resting heart rate: risk indicator and emerging risk factor in cardiovascular disease.
Böhm M, Reil JC, Deedwania P, Kim JB, Borer JS
Am J Med 2015 Mar;128(3):219-28. Epub 2014 Oct 15 doi: 10.1016/j.amjmed.2014.09.016. PMID: 25447617

Diagnosis

Associations of resting heart rate with incident dementia, cognition, and brain structure: a prospective cohort study of UK biobank.
Deng YT, Kuo K, Wu BS, Ou YN, Yang L, Zhang YR, Huang SY, Chen SD, Guo Y, Zhang RQ, Tan L, Dong Q, Feng JF, Cheng W, Yu JT
Alzheimers Res Ther 2022 Oct 5;14(1):147. doi: 10.1186/s13195-022-01088-3. PMID: 36199126Free PMC Article
The respiratory modulation of interoception.
Molle L, Coste A
J Neurophysiol 2022 Apr 1;127(4):896-899. Epub 2022 Mar 16 doi: 10.1152/jn.00027.2022. PMID: 35294271
Inappropriate sinus tachycardia: a review.
Ali M, Haji AQ, Kichloo A, Grubb BP, Kanjwal K
Rev Cardiovasc Med 2021 Dec 22;22(4):1331-1339. doi: 10.31083/j.rcm2204139. PMID: 34957774
Autonomic dysfunction in kidney diseases.
Lai S, Bagordo D, Perrotta AM, Gigante A, Gasperini ML, Muscaritoli M, Mazzaferro S, Cianci R
Eur Rev Med Pharmacol Sci 2020 Aug;24(16):8458-8468. doi: 10.26355/eurrev_202008_22643. PMID: 32894552
Resting heart rate and relation to disease and longevity: past, present and future.
Jensen MT
Scand J Clin Lab Invest 2019 Feb-Apr;79(1-2):108-116. Epub 2019 Feb 14 doi: 10.1080/00365513.2019.1566567. PMID: 30761923

Therapy

Effect of High-Intensity Interval Training in Patients With Atrial Fibrillation: A Randomized Clinical Trial.
Reed JL, Terada T, Vidal-Almela S, Tulloch HE, Mistura M, Birnie DH, Wells GA, Nair GM, Hans H, Way KL, Chirico D, O'Neill CD, Pipe AL
JAMA Netw Open 2022 Oct 3;5(10):e2239380. doi: 10.1001/jamanetworkopen.2022.39380. PMID: 36315143Free PMC Article
Resting heart rate and relation to disease and longevity: past, present and future.
Jensen MT
Scand J Clin Lab Invest 2019 Feb-Apr;79(1-2):108-116. Epub 2019 Feb 14 doi: 10.1080/00365513.2019.1566567. PMID: 30761923
Effects of high-intensity interval training on cardiometabolic health: a systematic review and meta-analysis of intervention studies.
Batacan RB Jr, Duncan MJ, Dalbo VJ, Tucker PS, Fenning AS
Br J Sports Med 2017 Mar;51(6):494-503. Epub 2016 Oct 20 doi: 10.1136/bjsports-2015-095841. PMID: 27797726
Isometric exercise training for blood pressure management: a systematic review and meta-analysis.
Carlson DJ, Dieberg G, Hess NC, Millar PJ, Smart NA
Mayo Clin Proc 2014 Mar;89(3):327-34. doi: 10.1016/j.mayocp.2013.10.030. PMID: 24582191
The Physical Activity Scale for the Elderly (PASE): development and evaluation.
Washburn RA, Smith KW, Jette AM, Janney CA
J Clin Epidemiol 1993 Feb;46(2):153-62. doi: 10.1016/0895-4356(93)90053-4. PMID: 8437031

Prognosis

Resting Heart Rate and Risk of Cancer Mortality.
Gutierrez-Martinez L, Brellenthin AG, Lefferts EC, Lee DC, Sui X, Lavie CJ, Blair SN
Cancer Epidemiol Biomarkers Prev 2021 Jun;30(6):1072-1078. Epub 2021 Apr 7 doi: 10.1158/1055-9965.EPI-20-1731. PMID: 33827985Free PMC Article
Cardiovascular Health Effects of Shift Work with Long Working Hours and Night Shifts: Study Protocol for a Three-Year Prospective Follow-Up Study on Industrial Workers.
Lunde LK, Skare Ø, Mamen A, Sirnes PA, Aass HCD, Øvstebø R, Goffeng E, Matre D, Nielsen P, Heglum HSA, Hammer SE, Skogstad M
Int J Environ Res Public Health 2020 Jan 16;17(2) doi: 10.3390/ijerph17020589. PMID: 31963313Free PMC Article
Resting heart rate in the supine and sitting positions as predictors of mortality in an elderly Chinese population.
Li FK, Sheng CS, Zhang DY, An DW, Huang JF, Li Y, Wang JG
J Hypertens 2019 Oct;37(10):2024-2031. doi: 10.1097/HJH.0000000000002134. PMID: 31107358
Ivabradine in Children With Dilated Cardiomyopathy and Symptomatic Chronic Heart Failure.
Bonnet D, Berger F, Jokinen E, Kantor PF, Daubeney PEF
J Am Coll Cardiol 2017 Sep 5;70(10):1262-1272. doi: 10.1016/j.jacc.2017.07.725. PMID: 28859790
Lenient versus strict rate control in patients with atrial fibrillation.
Van Gelder IC, Groenveld HF, Crijns HJ, Tuininga YS, Tijssen JG, Alings AM, Hillege HL, Bergsma-Kadijk JA, Cornel JH, Kamp O, Tukkie R, Bosker HA, Van Veldhuisen DJ, Van den Berg MP; RACE II Investigators
N Engl J Med 2010 Apr 15;362(15):1363-73. Epub 2010 Mar 15 doi: 10.1056/NEJMoa1001337. PMID: 20231232

Clinical prediction guides

Relationship of resting heart rate and blood pressure with all-cause and cardiovascular disease mortality.
He K, Chen X, Shi Z, Shi S, Tian Q, Hu X, Song R, Bai K, Shi W, Wang J, Li H, Ding J, Geng S, Sheng X
Public Health 2022 Jul;208:80-88. Epub 2022 Jun 18 doi: 10.1016/j.puhe.2022.03.020. PMID: 35728416
Elevated resting heart rate is associated with increased radiographic severity of knee but not hand joints.
Choi SE, Xu H, Kang JH, Park DJ, Kweon SS, Lee YH, Kim HY, Lee JK, Shin MH, Lee SS
Sci Rep 2021 Dec 8;11(1):23697. doi: 10.1038/s41598-021-03237-4. PMID: 34880392Free PMC Article
Six-minute walk distance in healthy young adults.
Halliday SJ, Wang L, Yu C, Vickers BP, Newman JH, Fremont RD, Huerta LE, Brittain EL, Hemnes AR
Respir Med 2020 Apr-May;165:105933. Epub 2020 Mar 19 doi: 10.1016/j.rmed.2020.105933. PMID: 32308201Free PMC Article
Resting heart rate: risk indicator and emerging risk factor in cardiovascular disease.
Böhm M, Reil JC, Deedwania P, Kim JB, Borer JS
Am J Med 2015 Mar;128(3):219-28. Epub 2014 Oct 15 doi: 10.1016/j.amjmed.2014.09.016. PMID: 25447617
The Physical Activity Scale for the Elderly (PASE): development and evaluation.
Washburn RA, Smith KW, Jette AM, Janney CA
J Clin Epidemiol 1993 Feb;46(2):153-62. doi: 10.1016/0895-4356(93)90053-4. PMID: 8437031

Recent systematic reviews

Isometric Resistance Training to Manage Hypertension: Systematic Review and Meta-analysis.
Baffour-Awuah B, Pearson MJ, Dieberg G, Smart NA
Curr Hypertens Rep 2023 Apr;25(4):35-49. Epub 2023 Feb 28 doi: 10.1007/s11906-023-01232-w. PMID: 36853479Free PMC Article
The effect of high-intensity interval training on exercise capacity in post-myocardial infarction patients: a systematic review and meta-analysis.
Qin Y, Kumar Bundhun P, Yuan ZL, Chen MH
Eur J Prev Cardiol 2022 Mar 25;29(3):475-484. doi: 10.1093/eurjpc/zwab060. PMID: 34279621
Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysis.
Kite C, Lahart IM, Afzal I, Broom DR, Randeva H, Kyrou I, Brown JE
Syst Rev 2019 Feb 12;8(1):51. doi: 10.1186/s13643-019-0962-3. PMID: 30755271Free PMC Article
Yoga, mindfulness-based stress reduction and stress-related physiological measures: A meta-analysis.
Pascoe MC, Thompson DR, Ski CF
Psychoneuroendocrinology 2017 Dec;86:152-168. Epub 2017 Aug 30 doi: 10.1016/j.psyneuen.2017.08.008. PMID: 28963884
Isometric exercise training for blood pressure management: a systematic review and meta-analysis.
Carlson DJ, Dieberg G, Hess NC, Millar PJ, Smart NA
Mayo Clin Proc 2014 Mar;89(3):327-34. doi: 10.1016/j.mayocp.2013.10.030. PMID: 24582191

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