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Glaucoma, normal tension, susceptibility to(NTG)

MedGen UID:
335756
Concept ID:
C1847730
Finding
Synonyms: GLAUCOMA, NORMAL PRESSURE, SUSCEPTIBILITY TO; NTG
 
Genes (locations): OPA1 (3q29); OPTN (10p13)
 
Monarch Initiative: MONDO:0011693
OMIM®: 606657

Professional guidelines

PubMed

Wu Z, Huang C, Zheng Y, Yuan XL, Chen S, Xu Y, Chen LJ, Pang CP, Zhang M, Ng TK
Mol Genet Genomics 2023 Nov;298(6):1343-1352. Epub 2023 Jul 29 doi: 10.1007/s00438-023-02058-6. PMID: 37516687

Recent clinical studies

Etiology

Loo Y, Chan ASY, Khor CC, Aung T, Wang Z
Mol Aspects Med 2024 Feb;95:101229. Epub 2023 Nov 30 doi: 10.1016/j.mam.2023.101229. PMID: 38039744
Chen YY, Wang TH, Huang JY, Su CC
Graefes Arch Clin Exp Ophthalmol 2022 Jan;260(1):255-264. Epub 2021 Aug 19 doi: 10.1007/s00417-021-05346-2. PMID: 34410485
Yanagisawa M, Namekata K, Aida T, Katou S, Takeda T, Harada T, Fuse N, The Glaucoma Gene Research Group, Tanaka K
Biochem Biophys Res Commun 2020 Sep 3;529(4):943-949. Epub 2020 Jul 30 doi: 10.1016/j.bbrc.2020.06.099. PMID: 32819603
Jung SH, Lee YC, Lee MY, Shin HY
Curr Eye Res 2020 Apr;45(4):521-525. Epub 2019 Oct 7 doi: 10.1080/02713683.2019.1668949. PMID: 31522561
Wiggs JL, Pasquale LR
Hum Mol Genet 2017 Aug 1;26(R1):R21-R27. doi: 10.1093/hmg/ddx184. PMID: 28505344Free PMC Article

Diagnosis

Chen YY, Wang TH, Huang JY, Su CC
Graefes Arch Clin Exp Ophthalmol 2022 Jan;260(1):255-264. Epub 2021 Aug 19 doi: 10.1007/s00417-021-05346-2. PMID: 34410485
Yue JL, Zheng SF
J Cell Mol Med 2021 Nov;25(21):9918-9926. Epub 2021 Oct 2 doi: 10.1111/jcmm.15906. PMID: 34599867Free PMC Article
Choung HK, Kim M, Oh S, Lee KM, Kim SH
PLoS One 2021;16(7):e0254889. Epub 2021 Jul 20 doi: 10.1371/journal.pone.0254889. PMID: 34283884Free PMC Article
Wiggs JL, Pasquale LR
Hum Mol Genet 2017 Aug 1;26(R1):R21-R27. doi: 10.1093/hmg/ddx184. PMID: 28505344Free PMC Article
Yamamoto T, Maeda M, Sawada A, Sugiyama K, Taniguchi T, Kitazawa Y, Oyama Z, Ichihashi N, Takagi H, Kitajima Y
Jpn J Ophthalmol 1999 Nov-Dec;43(6):539-42. doi: 10.1016/s0021-5155(99)00142-2. PMID: 10672886

Therapy

Lim CC, Lee CY, Huang FC, Huang JY, Hung JH, Yang SF
Int J Environ Res Public Health 2020 Sep 17;17(18) doi: 10.3390/ijerph17186774. PMID: 32957502Free PMC Article
Xin X, Gao L, Wu T, Sun F
Mol Vis 2013;19:526-35. Epub 2013 Feb 27 PMID: 23559847Free PMC Article
Nakamura-Yanagidaira T, Takahashi Y, Sano K, Murata T, Hayashi T
Mol Vis 2011;17:2157-70. Epub 2011 Aug 11 PMID: 21850191Free PMC Article
Hayreh SS, Podhajsky P, Zimmerman MB
Am J Ophthalmol 1999 Sep;128(3):301-9. doi: 10.1016/s0002-9394(99)00160-9. PMID: 10511024

Prognosis

Wu Z, Huang C, Zheng Y, Yuan XL, Chen S, Xu Y, Chen LJ, Pang CP, Zhang M, Ng TK
Mol Genet Genomics 2023 Nov;298(6):1343-1352. Epub 2023 Jul 29 doi: 10.1007/s00438-023-02058-6. PMID: 37516687
Beutgen VM, Pfeiffer N, Grus FH
Front Immunol 2021;12:616421. Epub 2021 Feb 19 doi: 10.3389/fimmu.2021.616421. PMID: 33679756Free PMC Article
Jung SH, Lee YC, Lee MY, Shin HY
Curr Eye Res 2020 Apr;45(4):521-525. Epub 2019 Oct 7 doi: 10.1080/02713683.2019.1668949. PMID: 31522561
Jung SH, Lee YC, Lee MY, Shin HY
Graefes Arch Clin Exp Ophthalmol 2019 Dec;257(12):2717-2721. Epub 2019 Sep 11 doi: 10.1007/s00417-019-04467-z. PMID: 31512042
Ritch R, Darbro B, Menon G, Khanna CL, Solivan-Timpe F, Roos BR, Sarfarzi M, Kawase K, Yamamoto T, Robin AL, Lotery AJ, Fingert JH
JAMA Ophthalmol 2014 May;132(5):544-8. doi: 10.1001/jamaophthalmol.2014.104. PMID: 24699864Free PMC Article

Clinical prediction guides

Wu Z, Huang C, Zheng Y, Yuan XL, Chen S, Xu Y, Chen LJ, Pang CP, Zhang M, Ng TK
Mol Genet Genomics 2023 Nov;298(6):1343-1352. Epub 2023 Jul 29 doi: 10.1007/s00438-023-02058-6. PMID: 37516687
Lee JS, Jeoung JW, Oh S, Kim DM, Ahn JH, Kim MJ, Seong MW, Park SS, Kim JY
Ophthalmic Genet 2020 Oct;41(5):427-431. Epub 2020 Jun 28 doi: 10.1080/13816810.2020.1783690. PMID: 32597291
Jung SH, Lee YC, Lee MY, Shin HY
Curr Eye Res 2020 Apr;45(4):521-525. Epub 2019 Oct 7 doi: 10.1080/02713683.2019.1668949. PMID: 31522561
Jung SH, Lee YC, Lee MY, Shin HY
Graefes Arch Clin Exp Ophthalmol 2019 Dec;257(12):2717-2721. Epub 2019 Sep 11 doi: 10.1007/s00417-019-04467-z. PMID: 31512042
Burdon KP, Awadalla MS, Mitchell P, Wang JJ, White A, Keane MC, Souzeau E, Graham SL, Goldberg I, Healey PR, Landers J, Mills RAD, Best S, Hewitt AW, Sharma S, Craig JE
Ophthalmic Genet 2018 Apr;39(2):221-227. Epub 2017 Dec 21 doi: 10.1080/13816810.2017.1413659. PMID: 29265947

Recent systematic reviews

Chaiwiang N, Poyomtip T
Biosci Rep 2019 Apr 30;39(4) Epub 2019 Apr 2 doi: 10.1042/BSR20190029. PMID: 30877182Free PMC Article
Liu K, He W, Zhao J, Zeng Y, Cheng H
Medicine (Baltimore) 2017 Jun;96(26):e7291. doi: 10.1097/MD.0000000000007291. PMID: 28658128Free PMC Article
Guo Y, Zhang H, Chen X, Yang X, Cheng W, Zhao K
Invest Ophthalmol Vis Sci 2012 Jun 20;53(7):3756-63. doi: 10.1167/iovs.12-9818. PMID: 22562509

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

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