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Congenital cleft nose

MedGen UID:
854359
•Concept ID:
C3887497
•
Congenital Abnormality
Synonyms: Bifid nose, autosomal recessive; MEDIAN FISSURE OF NOSE; NOSE, MEDIAN CLEFT OF
 
Monarch Initiative: MONDO:0008866
OMIM®: 210400

Definition

Autosomal recessive form of bifid nose. [from MONDO]

Professional guidelines

PubMed

Long-term treatment outcome of patients with complete bilateral cleft lip and palate: a retrospective cohort study.
Hattori Y, Pai BC, Saito T, Chou PY, Lu TC, Chang CS, Chen YR, Lo LJ
Int J Surg 2023 Jun 1;109(6):1656-1667. doi: 10.1097/JS9.0000000000000406. PMID: 37073546Free PMC Article
Cleft Lip Repair, Nasoalveolar Molding, and Primary Cleft Rhinoplasty.
Bhuskute AA, Tollefson TT
Facial Plast Surg Clin North Am 2016 Nov;24(4):453-466. doi: 10.1016/j.fsc.2016.06.015. PMID: 27712813
Cleft lip and palate: diagnosis and management.
Taib BG, Taib AG, Swift AC, van Eeden S
Br J Hosp Med (Lond) 2015 Oct;76(10):584-5, 588-91. doi: 10.12968/hmed.2015.76.10.584. PMID: 26457939

Recent clinical studies

Etiology

An essential overview of orofacial clefting.
Martin SV, Swan MC
Br Dent J 2023 Jun;234(12):937-942. Epub 2023 Jun 23 doi: 10.1038/s41415-023-6000-9. PMID: 37349450
Tessier 3 and 4 Clefts and Choanal Atresia: An Unusual Association?
Tonello C, Martins DANDP, Baptista MAFB, Mondelli F, Kokitsu Nakata NM, Feitosa LB, Alonso N
Cleft Palate Craniofac J 2022 Oct;59(10):1228-1232. Epub 2021 Sep 13 doi: 10.1177/10556656211042172. PMID: 34514882
Cleft Lip and Palate Repair.
Gatti GL, Freda N, Giacomina A, Montemagni M, Sisti A
J Craniofac Surg 2017 Nov;28(8):1918-1924. doi: 10.1097/SCS.0000000000003820. PMID: 29088690
Oro-Nasal Communication.
Sahoo NK, Desai AP, Roy ID, Kulkarni V
J Craniofac Surg 2016 Sep;27(6):e529-33. doi: 10.1097/SCS.0000000000002815. PMID: 27607130
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Diagnosis

Oronasal fistula post-septoplasty.
Alhedaithy RA, Alsaleh SA
Saudi Med J 2017 Mar;38(3):310-313. doi: 10.15537/smj.2017.3.16114. PMID: 28251229Free PMC Article
Cleft lip and palate: diagnosis and management.
Taib BG, Taib AG, Swift AC, van Eeden S
Br J Hosp Med (Lond) 2015 Oct;76(10):584-5, 588-91. doi: 10.12968/hmed.2015.76.10.584. PMID: 26457939
Raine syndrome: an overview.
Faundes V, Castillo-Taucher S, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B
Eur J Med Genet 2014 Sep;57(9):536-42. Epub 2014 Jul 12 doi: 10.1016/j.ejmg.2014.07.001. PMID: 25019372
Pediatric neck masses.
Goins MR, Beasley MS
Oral Maxillofac Surg Clin North Am 2012 Aug;24(3):457-68. doi: 10.1016/j.coms.2012.05.006. PMID: 22857718
Congenital atrichia and hypotrichosis.
Bennàssar A, Ferrando J, Grimalt R
World J Pediatr 2011 May;7(2):111-7. Epub 2011 May 15 doi: 10.1007/s12519-011-0262-z. PMID: 21574026

Therapy

"Should Pediatric Septal Surgery and Septorhinoplasty Be Performed for Nasal Obstruction?"-A Systematic Review of the Literature.
Howard T, Williams I, Navaratnam A, Haloob N, Stoenchev K, Saleh H
Facial Plast Surg 2024 Jun;40(3):378-393. Epub 2023 Nov 30 doi: 10.1055/a-2219-9266. PMID: 38035612
Clinical Features and Treatment of Congenital Pyriform Sinus Fistula: Analysis of 12 Cases.
Zhang S, Yuan Z, Xia Z, Chen H, Zhang Z, Chen M, Ye F
Ear Nose Throat J 2024 May;103(5):319-323. Epub 2022 Aug 13 doi: 10.1177/01455613221117004. PMID: 35968827
Bilateral Cleft Lip and Palate, With Facial Dysplasia: Interdisciplinary Treatment and Long-Term Follow-Up.
Bennun RD, Harfin JH
J Craniofac Surg 2018 Sep;29(6):1441-1444. doi: 10.1097/SCS.0000000000004756. PMID: 30015740
Cleft Lip and Palate Repair.
Gatti GL, Freda N, Giacomina A, Montemagni M, Sisti A
J Craniofac Surg 2017 Nov;28(8):1918-1924. doi: 10.1097/SCS.0000000000003820. PMID: 29088690
Surgical correction of bifid nose.
Tawfik A, El-Sisi HE, Abd El-Fattah AM
Int J Pediatr Otorhinolaryngol 2016 Jul;86:72-6. Epub 2016 Apr 20 doi: 10.1016/j.ijporl.2016.04.004. PMID: 27260584

Prognosis

Pyriform aperture enlargement in all aspects.
Esen E, Bayar Muluk N, Altintoprak N, Ipci K, Cingi C
J Laryngol Otol 2017 Jun;131(6):476-479. Epub 2017 Feb 27 doi: 10.1017/S0022215117000391. PMID: 28238296
Management of the Airway in Apert Syndrome.
Xie C, De S, Selby A
J Craniofac Surg 2016 Jan;27(1):137-41. doi: 10.1097/SCS.0000000000002333. PMID: 26674912
Raine syndrome: an overview.
Faundes V, Castillo-Taucher S, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B
Eur J Med Genet 2014 Sep;57(9):536-42. Epub 2014 Jul 12 doi: 10.1016/j.ejmg.2014.07.001. PMID: 25019372
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Maxillary sinus hypoplasia.
Erdem T, Aktas D, Erdem G, Miman MC, Ozturan O
Rhinology 2002 Sep;40(3):150-3. PMID: 12357716

Clinical prediction guides

An essential overview of orofacial clefting.
Martin SV, Swan MC
Br Dent J 2023 Jun;234(12):937-942. Epub 2023 Jun 23 doi: 10.1038/s41415-023-6000-9. PMID: 37349450
Craniofacial phenotypes associated with Robinow syndrome.
Conlon CJ, Abu-Ghname A, Raghuram AC, Davis MJ, Guillen DE, Sutton VR, Carvalho CMB, Maricevich RS
Am J Med Genet A 2021 Dec;185(12):3606-3612. Epub 2020 Nov 25 doi: 10.1002/ajmg.a.61986. PMID: 33237614
Patient- and 3D morphometry-based nose outcomes after skeletofacial reconstruction.
Denadai R, Chou PY, Seo HJ, Lonic D, Lin HH, Pai BCJ, Lo LJ
Sci Rep 2020 Mar 6;10(1):4246. doi: 10.1038/s41598-020-61233-6. PMID: 32144392Free PMC Article
Cleft Lip and Palate Repair.
Gatti GL, Freda N, Giacomina A, Montemagni M, Sisti A
J Craniofac Surg 2017 Nov;28(8):1918-1924. doi: 10.1097/SCS.0000000000003820. PMID: 29088690
The effect of hypoxia in development.
Webster WS, Abela D
Birth Defects Res C Embryo Today 2007 Sep;81(3):215-28. doi: 10.1002/bdrc.20102. PMID: 17963271

Recent systematic reviews

"Should Pediatric Septal Surgery and Septorhinoplasty Be Performed for Nasal Obstruction?"-A Systematic Review of the Literature.
Howard T, Williams I, Navaratnam A, Haloob N, Stoenchev K, Saleh H
Facial Plast Surg 2024 Jun;40(3):378-393. Epub 2023 Nov 30 doi: 10.1055/a-2219-9266. PMID: 38035612
Diprosopus: Systematic review and report of two cases.
Bidondo MP, Groisman B, Tardivo A, Tomasoni F, Tejeiro V, Camacho I, Vilas M, Liascovich R, Barbero P
Birth Defects Res A Clin Mol Teratol 2016 Dec;106(12):993-1007. Epub 2016 Oct 5 doi: 10.1002/bdra.23549. PMID: 27704687
Limited evidence for the effect of presurgical nasoalveolar molding in unilateral cleft on nasal symmetry: a call for unified research.
van der Heijden P, Dijkstra PU, Stellingsma C, van der Laan BF, Korsten-Meijer AGW, Goorhuis-Brouwer SM
Plast Reconstr Surg 2013 Jan;131(1):62e-71e. doi: 10.1097/PRS.0b013e318267d4a5. PMID: 23271555
Nasoalveolar molding in cleft care: is it efficacious?
Abbott MM, Meara JG
Plast Reconstr Surg 2012 Sep;130(3):659-666. doi: 10.1097/PRS.0b013e31825dc10a. PMID: 22929251

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