MedGen

Any focal segmental glomerulosclerosis in which the cause of the disease is a mutation in the CRB2 gene. [from MONDO]

Ventriculomegaly with cystic kidney disease (VMCKD) is a severe autosomal recessive developmental disorder characterized by onset in utero of dilated cerebral ventricles and microscopic renal tubular cysts. The pregnancies of affected individuals are associated with increased alpha-fetoprotein (AFP). Most affected pregnancies have been terminated (summary by Slavotinek et al., 2015). See also 602200 for a disorder characterized by ventriculomegaly and defects of the radius and kidney. [from OMIM]