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Complete trisomy 21 syndrome
Down syndrome, the most frequent form of mental retardation caused by a microscopically demonstrable chromosomal aberration, is characterized by well-defined and distinctive phenotypic features and natural history. It is caused by triplicate state (trisomy) of all or a critical portion of chromosome 21. [from OMIM]
Acute megakaryoblastic leukemia
A rare subtype of acute myeloid leukemia evolving from primitive megakaryoblasts. [from HPO]
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