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Chronic discoid lupus erythematosus

MedGen UID:
7402
Concept ID:
C0024138
Disease or Syndrome
Synonyms: Discoid Lupus Erythematosus; Lupus Erythematosus, Chronic Cutaneous; Lupus Erythematosus, Cutaneous, Chronic; Lupus Erythematosus, Discoid
SNOMED CT: CDLE - Chronic discoid lupus erythematosus (238927000); Chronic discoid lupus erythematosus (238927000)

Definition

A chronic, autoimmune skin condition that manifests with a red, scaling rash, most often found on the face, ears, and scalp; these lesions often lead to permanent scarring and dyspigmentation. Patients may have lesions with or without other symptoms or antibodies suggestive of systemic lupus erythematosus (SLE). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic discoid lupus erythematosus
Follow this link to review classifications for Chronic discoid lupus erythematosus in Orphanet.

Professional guidelines

PubMed

Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Knop J, Bonsmann G, Happle R, Ludolph A, Matz DR, Mifsud EJ, Macher E
Br J Dermatol 1983 Apr;108(4):461-6. doi: 10.1111/j.1365-2133.1983.tb04600.x. PMID: 6838771
REES RB, BENNETT JH, GREENLEE MR
Calif Med 1959 Jul;91(1):1-5. PMID: 13662855Free PMC Article

Recent clinical studies

Etiology

Ju T, Ingrasci G, Diaz-Perez JA, Obayomi A, Yosipovitch G
J Cutan Pathol 2023 Jan;50(1):19-23. Epub 2022 Aug 23 doi: 10.1111/cup.14304. PMID: 35922371
Kluger N, Andraud M, Lartigau-Roussin C, Sultan-Bichat N
Acta Dermatovenerol Alp Pannonica Adriat 2021 Mar;30(1):43-46. PMID: 33765758
Gao X, Ma L, Zhou Z, Jian X, Liu W
Int J Surg Pathol 2016 Oct;24(7):595-9. Epub 2016 May 29 doi: 10.1177/1066896916652220. PMID: 27240861
Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993

Diagnosis

Pramatarov KD
Clin Dermatol 2004 Mar-Apr;22(2):113-20. doi: 10.1016/j.clindermatol.2003.12.016. PMID: 15234011
Kulthanan K, Roongphiboolsopit P, Chanjanakijskul S, Kullavanijaya P
Int J Dermatol 1996 Oct;35(10):711-4. doi: 10.1111/j.1365-4362.1996.tb00643.x. PMID: 8891819
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993
Winkelmann RK
JAMA 1968 Sep 2;205(10):675-8. PMID: 5695138
ROTHFIELD N, MARCH CH, MIESCHER P, MCEWEN C
N Engl J Med 1963 Nov 28;269:1155-61. doi: 10.1056/NEJM196311282692201. PMID: 14061123

Therapy

Steinbronn C, Chhonker YS, Stewart J, Leingang H, Heller KB, Krows ML, Paasche-Orlow M, Bershteyn A, Stankiewicz Karita HC, Agrawal V, Laufer M, Landovitz R, Wener M, Murry DJ, Johnston C, Barnabas RV, Arnold SLM
Clin Transl Sci 2023 Jul;16(7):1243-1257. Epub 2023 Apr 29 doi: 10.1111/cts.13527. PMID: 37118968Free PMC Article
Jin X, Lu S, Xing X, Wang L, Mu D, He M, Huang H, Zeng X, Chen Q
J Oral Pathol Med 2013 May;42(5):355-62. Epub 2012 Sep 17 doi: 10.1111/jop.12004. PMID: 22978368
Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Perri AJ 3rd, Hsu S
Dermatol Online J 2003 Aug;9(3):5. PMID: 12952752
Winkelmann RK
JAMA 1968 Sep 2;205(10):675-8. PMID: 5695138

Prognosis

Dadlani C, Pulitzer M, Prystowsky SD
Dermatol Online J 2008 May 15;14(5):5. PMID: 18627741
Kyriakis KP, Kontochristopoulos GJ, Panteleos DN
Int J Dermatol 2000 Mar;39(3):218-22. doi: 10.1046/j.1365-4362.2000.00953.x. PMID: 10759967
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993
Callen JP
Arch Dermatol 1982 Jun;118(6):412-6. doi: 10.1001/archderm.118.6.412. PMID: 7092253
Bresnihan B, Hughes GR
Ann Rheum Dis 1977 Oct;36(5):476-7. doi: 10.1136/ard.36.5.476. PMID: 303502Free PMC Article

Clinical prediction guides

Steinbronn C, Chhonker YS, Stewart J, Leingang H, Heller KB, Krows ML, Paasche-Orlow M, Bershteyn A, Stankiewicz Karita HC, Agrawal V, Laufer M, Landovitz R, Wener M, Murry DJ, Johnston C, Barnabas RV, Arnold SLM
Clin Transl Sci 2023 Jul;16(7):1243-1257. Epub 2023 Apr 29 doi: 10.1111/cts.13527. PMID: 37118968Free PMC Article
Weiss A, Kwon EJ, Kreidel M, Mann R, Cohen JA, Hui Y, Jacobson MI
Am J Dermatopathol 2020 Feb;42(2):129-132. doi: 10.1097/DAD.0000000000001510. PMID: 31464721
Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Kulthanan K, Roongphiboolsopit P, Chanjanakijskul S, Kullavanijaya P
Int J Dermatol 1996 Oct;35(10):711-4. doi: 10.1111/j.1365-4362.1996.tb00643.x. PMID: 8891819
Callen JP
Arch Dermatol 1982 Jun;118(6):412-6. doi: 10.1001/archderm.118.6.412. PMID: 7092253

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