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Joint laxity

MedGen UID:
39439
Concept ID:
C0086437
Finding
Synonyms: Hypermobilities, Joint; Hypermobility, Joint; Joint Hypermobilities; Joint Hypermobility; Joint Laxities; Joint Laxity; Laxities, Joint; Laxity, Joint
SNOMED CT: Joint laxity (298203008)

Definition

Looseness or instability of a joint. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Oppermann H, Marcos-Grañeda E, Weiss LA, Gurnett CA, Jelsig AM, Vineke SH, Isidor B, Mercier S, Magnussen K, Zacher P, Hashim M, Pagnamenta AT, Race S, Srivastava S, Frazier Z, Maiwald R, Pergande M, Milani D, Rinelli M, Levy J, Krey I, Fontana P, Lonardo F, Riley S, Kretzer J, Rankin J, Reis LM, Semina EV, Reuter MS, Scherer SW, Iascone M, Weis D, Fagerberg CR, Brasch-Andersen C, Hansen LK, Kuechler A, Noble N, Gardham A, Tenney J, Rathore G, Beck-Woedl S, Haack TB, Pavlidou DC, Atallah I, Vodopiutz J, Janecke AR, Hsieh TC, Lesmann H, Klinkhammer H, Krawitz PM, Lemke JR, Jamra RA, Nieto M, Tümer Z, Platzer K
Eur J Hum Genet 2023 Nov;31(11):1251-1260. Epub 2023 Aug 30 doi: 10.1038/s41431-023-01445-2. PMID: 37644171Free PMC Article
Jacob P, Bhavani GSL, Shah H, Galada C, Nampoothiri S, Kamath N, Phadke SR, Muranjan M, Datar CA, Shukla A, Girisha KM
Am J Med Genet A 2022 Mar;188(3):751-759. Epub 2021 Nov 9 doi: 10.1002/ajmg.a.62566. PMID: 34750995
Rice DA, McNair PJ
Semin Arthritis Rheum 2010 Dec;40(3):250-66. Epub 2009 Dec 2 doi: 10.1016/j.semarthrit.2009.10.001. PMID: 19954822

Recent clinical studies

Etiology

Atwell K, Michael W, Dubey J, James S, Martonffy A, Anderson S, Rudin N, Schrager S
J Am Board Fam Med 2021 Jul-Aug;34(4):838-848. doi: 10.3122/jabfm.2021.04.200374. PMID: 34312277
Hansen M, Kjaer M
Adv Exp Med Biol 2016;920:139-49. doi: 10.1007/978-3-319-33943-6_13. PMID: 27535256
Hill L, Collins M, Posthumus M
Phys Sportsmed 2015 Nov;43(4):412-20. Epub 2015 Sep 14 doi: 10.1080/00913847.2015.1077097. PMID: 26366502
Zhang Y, Jordan JM
Clin Geriatr Med 2010 Aug;26(3):355-69. doi: 10.1016/j.cger.2010.03.001. PMID: 20699159Free PMC Article
Rice DA, McNair PJ
Semin Arthritis Rheum 2010 Dec;40(3):250-66. Epub 2009 Dec 2 doi: 10.1016/j.semarthrit.2009.10.001. PMID: 19954822

Diagnosis

Velchev JD, Van Laer L, Luyckx I, Dietz H, Loeys B
Adv Exp Med Biol 2021;1348:251-264. doi: 10.1007/978-3-030-80614-9_11. PMID: 34807423
Atwell K, Michael W, Dubey J, James S, Martonffy A, Anderson S, Rudin N, Schrager S
J Am Board Fam Med 2021 Jul-Aug;34(4):838-848. doi: 10.3122/jabfm.2021.04.200374. PMID: 34312277
Casagrande D, Gugala Z, Clark SM, Lindsey RW
J Am Acad Orthop Surg 2015 Sep;23(9):539-49. Epub 2015 Aug 13 doi: 10.5435/JAAOS-D-14-00248. PMID: 26271756
Dallinga JM, Benjaminse A, Lemmink KA
Sports Med 2012 Sep 1;42(9):791-815. doi: 10.1007/BF03262295. PMID: 22909185
Wolf JM, Cameron KL, Owens BD
J Am Acad Orthop Surg 2011 Aug;19(8):463-71. doi: 10.5435/00124635-201108000-00002. PMID: 21807914

Therapy

Chen G, Olver JS, Kanaan RA
J Psychosom Res 2021 Sep;148:110556. Epub 2021 Jun 24 doi: 10.1016/j.jpsychores.2021.110556. PMID: 34237584
Tsikopoulos K, Sidiropoulos K, Kitridis D, Cain Atc SM, Metaxiotis D, Ali A
Clin Orthop Relat Res 2020 Feb;478(2):359-377. doi: 10.1097/CORR.0000000000000946. PMID: 31625960Free PMC Article
Hughes L, Rosenblatt B, Haddad F, Gissane C, McCarthy D, Clarke T, Ferris G, Dawes J, Paton B, Patterson SD
Sports Med 2019 Nov;49(11):1787-1805. doi: 10.1007/s40279-019-01137-2. PMID: 31301034
Rice DA, McNair PJ
Semin Arthritis Rheum 2010 Dec;40(3):250-66. Epub 2009 Dec 2 doi: 10.1016/j.semarthrit.2009.10.001. PMID: 19954822
Zech A, Hübscher M, Vogt L, Banzer W, Hänsel F, Pfeifer K
Med Sci Sports Exerc 2009 Oct;41(10):1831-41. doi: 10.1249/MSS.0b013e3181a3cf0d. PMID: 19727032

Prognosis

Lim JR, Lee HM, Yoon TH, Lee HM, Chun YM
Am J Sports Med 2021 Dec;49(14):3981-3987. Epub 2021 Oct 25 doi: 10.1177/03635465211049221. PMID: 34694163
Dallinga JM, Benjaminse A, Lemmink KA
Sports Med 2012 Sep 1;42(9):791-815. doi: 10.1007/BF03262295. PMID: 22909185
Zhang Y, Jordan JM
Clin Geriatr Med 2010 Aug;26(3):355-69. doi: 10.1016/j.cger.2010.03.001. PMID: 20699159Free PMC Article
Felson DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick CG, Jordan JM, Kington RS, Lane NE, Nevitt MC, Zhang Y, Sowers M, McAlindon T, Spector TD, Poole AR, Yanovski SZ, Ateshian G, Sharma L, Buckwalter JA, Brandt KD, Fries JF
Ann Intern Med 2000 Oct 17;133(8):635-46. doi: 10.7326/0003-4819-133-8-200010170-00016. PMID: 11033593
Arendt E, Dick R
Am J Sports Med 1995 Nov-Dec;23(6):694-701. doi: 10.1177/036354659502300611. PMID: 8600737

Clinical prediction guides

Kim MS, Kim JJ, Kang KH, Sin KJ, In Y
J Arthroplasty 2023 Apr;38(4):662-667. Epub 2022 Oct 27 doi: 10.1016/j.arth.2022.10.033. PMID: 36309143
Lim JR, Lee HM, Yoon TH, Lee HM, Chun YM
Am J Sports Med 2021 Dec;49(14):3981-3987. Epub 2021 Oct 25 doi: 10.1177/03635465211049221. PMID: 34694163
Tsikopoulos K, Sidiropoulos K, Kitridis D, Cain Atc SM, Metaxiotis D, Ali A
Clin Orthop Relat Res 2020 Feb;478(2):359-377. doi: 10.1097/CORR.0000000000000946. PMID: 31625960Free PMC Article
Czaprowski D, Kotwicki T, Stoliński L
Ortop Traumatol Rehabil 2012 Sep-Oct;14(5):407-20. doi: 10.5604/15093492.1016368. PMID: 23208932
Dallinga JM, Benjaminse A, Lemmink KA
Sports Med 2012 Sep 1;42(9):791-815. doi: 10.1007/BF03262295. PMID: 22909185

Recent systematic reviews

Chen G, Olver JS, Kanaan RA
J Psychosom Res 2021 Sep;148:110556. Epub 2021 Jun 24 doi: 10.1016/j.jpsychores.2021.110556. PMID: 34237584
Krebs NM, Barber-Westin S, Noyes FR
Arthroscopy 2021 Jul;37(7):2337-2347. Epub 2021 Feb 20 doi: 10.1016/j.arthro.2021.02.021. PMID: 33621648
Tsikopoulos K, Sidiropoulos K, Kitridis D, Cain Atc SM, Metaxiotis D, Ali A
Clin Orthop Relat Res 2020 Feb;478(2):359-377. doi: 10.1097/CORR.0000000000000946. PMID: 31625960Free PMC Article
Hill L, Collins M, Posthumus M
Phys Sportsmed 2015 Nov;43(4):412-20. Epub 2015 Sep 14 doi: 10.1080/00913847.2015.1077097. PMID: 26366502
Dallinga JM, Benjaminse A, Lemmink KA
Sports Med 2012 Sep 1;42(9):791-815. doi: 10.1007/BF03262295. PMID: 22909185

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