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Ataxin-2

A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.

Year introduced: 2016

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Tree Number(s): D12.776.157.725.452.125, D12.776.631.069.750, D12.776.660.075.750, D12.776.664.962.452.125

MeSH Unique ID: D000067698

Entry Terms:

  • Ataxin 2
  • Atx-2 Protein
  • Atx 2 Protein
  • Protein, Atx-2
  • SCA2 Protein
  • Protein, SCA2
  • Spinocerebellar Ataxia Type 2 Protein
  • ATXN2 Protein
  • Protein, ATXN2
  • Ataxin-2 Protein
  • Ataxin 2 Protein
  • Protein, Ataxin-2

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