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Ataxin-3

A deubiquitinating enzyme of the ATAXINS family. It functions in protein homeostasis, GENETIC TRANSCRIPTION; CYTOSKELETON regulation, and MYOGENESIS. CAG TRINUCLEOTIDE REPEAT EXPANSION in the Ataxin-3 gene coding region is associated with spinocerebellar ataxia-3 (MACHADO-JOSEPH DISEASE).

Year introduced: 2016 (1995)

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Tree Number(s): D08.811.037.250, D12.776.631.069.875, D12.776.660.075.875

MeSH Unique ID: D000067699

Registry Number: EC 3.4.19.12

Entry Terms:

  • Ataxin 3
  • Spinocerebellar Ataxia 3 Protein
  • ATXN3 Protein
  • Ataxin-3 Protein
  • Ataxin 3 Protein
  • Machado-Joseph Disease Protein
  • Machado Joseph Disease Protein
  • SCA3 Protein

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